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Plastome sequencing reveals phylogenetic relationships among Comastoma and related taxa (Gentianaceae) from the Qinghai-Tibetan Plateau 期刊论文
ECOLOGY AND EVOLUTION, 2021, 卷号: 11, 期号: 22
作者:  Zhang, Yu;  Yu, Jingya;  Xia, Mingze;  Chi, Xiaofeng;  Khan, Gulzar;  Chen, Shilong;  Zhang, Faqi
收藏  |  浏览/下载：46/0  |  提交时间：2022/04/28
MOLECULAR PHYLOGENY  CHLOROPLAST GENOME  RIBOSOMAL-PROTEIN  NUCLEAR  EVOLUTION  DNA  DIVERSIFICATION  ALIGNMENT  BIODIVERSITY  ANGIOSPERMS  
Valence and patterning of aromatic residues determine the phase behavior of prion-like domains 期刊论文
, 2020, 卷号: 367, 期号: 6478
作者:  Martin E.W.;  Holehouse A.S.;  Peran I.;  Farag M.;  Incicco J.J.;  Bremer A.;  Grace C.R.;  Soranno A.;  Pappu R.V.;  Mittag T.
收藏  |  浏览/下载：21/0  |  提交时间：2020/07/28
aromatic hydrocarbon  biophysics  concentration (composition)  genetic analysis  nuclear magnetic resonance  prion disease  protein  separation  temperature effect  article  nonhuman  nuclear magnetic resonance spectroscopy  phase separation  prediction  prion  simulation  X ray crystallography  amino acid sequence  chemistry  phase transition  prion  protein domain  small angle scattering  X ray diffraction  heterogeneous nuclear ribonucleoprotein A1  phenylalanine  tyrosine  Amino Acid Sequence  Heterogeneous Nuclear Ribonucleoprotein A1  Magnetic Resonance Spectroscopy  Phase Transition  Phenylalanine  Prions  Protein Domains  Scattering, Small Angle  Tyrosine  X-Ray Diffraction  
Total synthesis reveals atypical atropisomerism in a small-molecule natural product, tryptorubin A 期刊论文
, 2020, 卷号: 367, 期号: 6476
作者:  Reisberg S.H.;  Gao Y.;  Walker A.S.;  Helfrich E.J.N.;  Clardy J.;  Baran P.S.
收藏  |  浏览/下载：43/0  |  提交时间：2020/07/28
alkaloid  tryptorubin A  unclassified drug  alkaloid  connectivity  molecular analysis  peptide  alkylation  Article  bioinformatics  carbon nuclear magnetic resonance  chemical structure  chirality  cyclization  dehydrogenation  high performance liquid chromatography  hydrogen bond  hydrophobicity  isomerism  nonhuman  nuclear magnetic resonance spectroscopy  oxidation  priority journal  protein processing  proton nuclear magnetic resonance  stereochemistry  Streptomyces  synthesis  X ray crystallography  
The histone H3-H4 tetramer is a copper reductase enzyme 期刊论文
, 2020, 卷号: 369, 期号: 6499
作者:  Attar N.;  Campos O.A.;  Vogelauer M.;  Cheng C.;  Xue Y.;  Schmollinger S.;  Salwinski L.;  Mallipeddi N.V.;  Boone B.A.;  Yen L.;  Yang S.;  Zikovich S.;  Dardine J.;  Carey M.F.;  Merchant S.S.;  Kurdistani S.K.
收藏  |  浏览/下载：28/0  |  提交时间：2020/07/28
copper  copper oxidase  copper zinc superoxide dismutase  histone  MAC1 protein, S cerevisiae  nuclear protein  oxidoreductase  recombinant protein  Saccharomyces cerevisiae protein  transcription factor  animal  biocatalysis  chemistry  enzyme active site  enzymology  gain of function mutation  genetics  metabolism  mitochondrion  protein multimerization  Saccharomyces cerevisiae  Xenopus laevis  Animals  Biocatalysis  Catalytic Domain  Copper  Gain of Function Mutation  Histones  Mitochondria  Nuclear Proteins  Oxidoreductases  Protein Multimerization  Recombinant Proteins  Saccharomyces cerevisiae  Saccharomyces cerevisiae Proteins  Superoxide Dismutase-1  Transcription Factors  Xenopus laevis  
Partitioning of cancer therapeutics in nuclear condensates 期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:  Klein I.A.;  Boija A.;  Afeyan L.K.;  Hawken S.W.;  Fan M.;  Dall'Agnese A.;  Oksuz O.;  Henninger J.E.;  Shrinivas K.;  Sabari B.R.;  Sagi I.;  Clark V.E.;  Platt J.M.;  Kar M.;  McCall P.M.;  Zamudio A.V.;  Manteiga J.C.;  Coffey E.L.;  Li C.H.;  Hannett N.M.;  Guo Y.E.;  Decker T.-M.;  Lee T.I.;  Zhang T.;  Weng J.-K.;  Taatjes D.J.;  Chakraborty A.;  Sharp P.A.;  Chang Y.T.;  Hyman A.A.;  Gray N.S.;  Young R.A.
收藏  |  浏览/下载：40/0  |  提交时间：2020/07/28
cancer  condensate  disease  drug  physicochemical property  protein  tumor  antineoplastic agent  BRD4 protein, human  cell cycle protein  green fluorescent protein  heterochromatin-specific nonhistone chromosomal protein HP-1  MED1 protein, human  nonhistone protein  nuclear protein  nucleophosmin  peroxisome proliferator activated receptor binding protein  recombinant protein  serine arginine rich splicing factor  SRSF2 protein, human  transcription factor  cell nucleus  drug resistance  genetics  human  metabolism  neoplasm  Antineoplastic Agents  Cell Cycle Proteins  Cell Nucleus  Chromosomal Proteins, Non-Histone  Drug Resistance, Neoplasm  Green Fluorescent Proteins  Humans  Mediator Complex Subunit 1  Neoplasms  Nuclear Proteins  Recombinant Proteins  Serine-Arginine Splicing Factors  Transcription Factors  
Structural basis for transcriptional start site control of HIV-1 RNA fate 期刊论文
, 2020, 卷号: 368, 期号: 6489
作者:  Brown J.D.;  Kharytonchyk S.;  Chaudry I.;  Iyer A.S.;  Carter H.;  Becker G.;  Desai Y.;  Glang L.;  Choi S.H.;  Singh K.;  Lopresti M.W.;  Orellana M.;  Rodriguez T.;  Oboh U.;  Hijji J.;  Ghinger F.G.;  Stewart K.;  Francis D.;  Edwards B.;  Chen P.;  Case D.A.;  Telesnitsky A.;  Summers M.F.
收藏  |  浏览/下载：41/0  |  提交时间：2020/07/28
capped RNA  initiation factor 4E  messenger RNA  virus RNA  capped RNA  guanosine  initiation factor 4E  messenger RNA  virus RNA  cell  chemical binding  deuterium  genome  human immunodeficiency virus  physiological response  RNA  Article  base pairing  deuteron nuclear magnetic resonance  dimerization  DNA helix  energy transfer  gene control  gene function  gene number  human  Human immunodeficiency virus 1  nonhuman  priority journal  promoter region  RNA probe  RNA structure  RNA transcription  virus replication  5' untranslated region  base pairing  chemistry  DNA base composition  gene expression regulation  genetics  Human immunodeficiency virus 1  metabolism  nuclear magnetic resonance  protein synthesis  transcription initiation site  Eukaryota  Human immunodeficiency virus 1  5' Untranslated Regions  Base Composition  Base Pairing  Eukaryotic Initiation Factor-4E  Gene Expression Regulation, Viral  Guanosine  HIV-1  Humans  Nuclear Magnetic Resonance, Biomolecular  Protein Biosynthesis  RNA Caps  RNA, Messenger  RNA, Viral  Transcription Initiation Site  
Democratizing cryo-EM: Broadening access to an expanding field 期刊论文
, 2020, 卷号: 367, 期号: 6484
作者:  Tachibana C.
收藏  |  浏览/下载：194/0  |  提交时间：2020/07/28
membrane protein  nucleic acid  democratization  detection method  electron microscopy  algorithm  Article  conformational transition  cryoelectron microscopy  crystallization  electron diffraction  electron tomography  freezing  glycosylation  human  microcrystal electron diffraction  nanoimaging  nuclear magnetic resonance spectroscopy  priority journal  protein processing  protein structure  protein synthesis  social welfare  transmission electron microscopy  X ray crystallography  
Structure of an active human histone pre-mRNA 3′-end processing machinery 期刊论文
, 2020, 卷号: 367, 期号: 6478
作者:  Sun Y.;  Zhang Y.;  Aik W.S.;  Yang X.-C.;  Marzluff W.F.;  Walz T.;  Dominski Z.;  Tong L.
收藏  |  浏览/下载：221/0  |  提交时间：2020/07/28
beta lactamase  cleavage and polyadenylation specificity factor  cleavage and polyadenylation specificity factor 100  cleavage and polyadenylation specificity factor 73  endonuclease  histone  membrane protein  messenger RNA precursor  recombinant protein  small nuclear ribonucleoprotein  small nuclear RNA  symplekin  U7 small nuclear ribonucleoprotein  unclassified drug  enzyme activity  genetic analysis  metazoan  protein  recombination  RNA  3' untranslated region  amino terminal sequence  Article  biochemical analysis  carboxy terminal sequence  conformational transition  controlled study  cryoelectron microscopy  enzyme active site  gene rearrangement  genetic analysis  hydrogen bond  molecular recognition  mutagenesis  polyadenylation  priority journal  protein conformation  protein protein interaction  RNA cleavage  RNA processing  RNA sequencing  Amphora  Metazoa