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文献类型
期刊论文 [7]
发表日期
2020 [7]
语种
英语 [7]
来源机构
Science [7]
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Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations
期刊论文
, 2020, 卷号: 367, 期号: 6478
作者:
Wilmes S.
;
Hafer M.
;
Vuorio J.
;
Tucker J.A.
;
Winkelmann H.
;
Löchte S.
;
Stanly T.A.
;
Pulgar Prieto K.D.
;
Poojari C.
;
Sharma V.
;
Richter C.P.
;
Kurre R.
;
Hubbard S.R.
;
Christopher Garcia K.
;
Moraga I.
;
Vattulainen I.
;
Hitchcock I.S.
;
Piehler J.
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2020/07/28
cytokine receptor
homodimer
Janus kinase 2
ligand
oncoprotein
cancer
enzyme
enzyme activity
membrane
molecular analysis
mutation
protein
activation analysis
Article
cell membrane
computer model
controlled study
dimerization
fluorescence microscopy
gene mutation
HeLa cell line
molecular dynamics
mutant
oncogene
priority journal
protein domain
protein interaction
quantitative analysis
signal transduction
T cells with dysfunctional mitochondria induce multimorbidity and premature senescence
期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:
Desdín-Micó G.
;
Soto-Heredero G.
;
Aranda J.F.
;
Oller J.
;
Carrasco E.
;
Gabandé-Rodríguez E.
;
Blanco E.M.
;
Alfranca A.
;
Cussó L.
;
Desco M.
;
Ibañez B.
;
Gortazar A.R.
;
Fernández-Marcos P.
;
Navarro M.N.
;
Hernaez B.
;
Alcamí A.
;
Baixauli F.
;
Mittelbrunn M.
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2020/07/28
cardiovascular disease
enzyme activity
gene expression
metabolism
mitochondrial DNA
morbidity
senescence
tumor
Mus
DNA binding protein
mitochondrial protein
mitochondrial transcription factor A
nicotinamide adenine dinucleotide
transcription factor
tumor necrosis factor
animal
cytokine release syndrome
female
fitness
gene deletion
genetics
immunology
inflammation
longevity
male
metabolism
mitochondrion
mouse
multiple chronic conditions
mutant mouse strain
premature aging
T lymphocyte
ultrastructure
Aging, Premature
Animals
Cytokine Release Syndrome
DNA-Binding Proteins
Female
Gene Deletion
Inflammation
Longevity
Male
Mice
Mice, Mutant Strains
Mitochondria
Mitochondrial Proteins
Multimorbidity
NAD
Physical Fitness
T-Lymphocytes
Transcription Factors
Tumor Necrosis Factor-alpha
Widespread receptor-driven modulation in peripheral olfactory coding
期刊论文
, 2020, 卷号: 368, 期号: 6487
作者:
Xu L.
;
Li W.
;
Voleti V.
;
Zou D.-J.
;
Hillman E.M.C.
;
Firestein S.
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/07/28
antagonism
cell component
detection method
odor
olfaction
protein
animal cell
animal experiment
article
excitation
high throughput analysis
male
microscopy
mouse
nonhuman
odor
olfactory epithelium
olfactory receptor neuron
animal
confocal microscopy
innervation
mutant mouse strain
olfactory mucosa
physiology
single cell analysis
acetophenone
acetophenone derivative
benzyl acetate
benzyl derivative
citral
fragrance
Acetophenones
Acyclic Monoterpenes
Animals
Benzyl Compounds
Mice
Mice, Mutant Strains
Microscopy, Confocal
Odorants
Olfactory Mucosa
Olfactory Receptor Neurons
Single-Cell Analysis
Smell
Dendritic cell-derived hepcidin sequesters iron from the microbiota to promote mucosal healing
期刊论文
, 2020, 卷号: 368, 期号: 6487
作者:
Bessman N.J.
;
Mathieu J.R.R.
;
Renassia C.
;
Zhou L.
;
Fung T.C.
;
Fernandez K.C.
;
Austin C.
;
Moeller J.B.
;
Zumerle S.
;
Louis S.
;
Vaulont S.
;
Ajami N.J.
;
Sokol H.
;
Putzel G.G.
;
Arvedson T.
;
Sockolow R.E.
;
Lakhal-Littleton S.
;
Cloonan S.M.
;
Arora M.
;
Peyssonnaux C.
;
Sonnenberg G.F.
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/07/28
ferroportin
hepcidin
iron
cation transport protein
Hamp protein, mouse
hepcidin
iron
metal transporting protein 1
cell
digestive system disorder
immunity
iron
microorganism
animal cell
animal experiment
animal model
animal tissue
Article
controlled study
dendritic cell
enteritis
healing
immunity
intestine flora
intestine injury
iron blood level
iron homeostasis
iron metabolism
iron sequestration
mouse
mucosal healing
mucosal immunity
nonhuman
nutritional immunity
phagocyte
priority journal
protein expression
tissue regeneration
tissue repair
animal
dendritic cell
enteropathy
fecal microbiota transplantation
gene deletion
genetics
homeostasis
intestine mucosa
metabolism
microbiology
mutant mouse strain
physiology
Mus
Animals
Cation Transport Proteins
Dendritic Cells
Fecal Microbiota Transplantation
Gastrointestinal Microbiome
Gene Deletion
Hepcidins
Homeostasis
Intestinal Diseases
Intestinal Mucosa
Iron
Mice
Mice, Mutant Strains
Phagocytes
TTC5 mediates autoregulation of tubulin via mRNA degradation
期刊论文
, 2020, 卷号: 367, 期号: 6473
作者:
Lin Z.
;
Gasic I.
;
Chandrasekaran V.
;
Peters N.
;
Shao S.
;
Mitchison T.J.
;
Hegde R.S.
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/28
messenger RNA
mutant protein
polypeptide
recombinant protein
regulator protein
tetratricopeptide protein 5
tubulin
unclassified drug
biodegradation
chromosome
peptide
protein
RNA
amino terminal sequence
animal cell
Article
autoregulation
binding site
chromosome segregation
controlled study
cryoelectron microscopy
genetic code
human
human cell
Leporidae
mitosis
molecular model
nonhuman
priority journal
protein analysis
protein binding
protein interaction
protein structure
reticulocyte
ribosome
RNA degradation
RNA translation
tubulin gene
A two-way molecular dialogue between embryo and endosperm is required for seed development
期刊论文
, 2020, 卷号: 367, 期号: 6476
作者:
Doll N.M.
;
Royek S.
;
Fujita S.
;
Okuda S.
;
Chamot S.
;
Stintzi A.
;
Widiez T.
;
Hothorn M.
;
Schaller A.
;
Geldner N.
;
Ingram G.
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2020/07/28
GASSHO receptor
plant protein
twisted seed1
unclassified drug
cuticle
embryo
enzyme activity
gene expression
germination
molecular analysis
peptide
signaling
Article
controlled study
endosperm
germination
mutant
nonhuman
plant embryo
plant seed
priority journal
protein cleavage
protein function
seed development
signal transduction
sulfation
Dermal sheath contraction powers stem cell niche relocation during hair cycle regression
期刊论文
, 2020, 卷号: 367, 期号: 6474
作者:
Heitman N.
;
Sennett R.
;
Mok K.-W.
;
Saxena N.
;
Srivastava D.
;
Martino P.
;
Grisanti L.
;
Wang Z.
;
Ma'ayan A.
;
Rompolas P.
;
Rendl M.
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/28
aggrecan
calcium
calmodulin
myosin light chain kinase
cell component
enzyme
enzyme activity
growth
hair
homeostasis
muscle
skin
animal cell
animal tissue
Article
controlled study
cutaneous parameters
dermal sheath contraction
hair cycle regression
hair follicle
hair root
in vivo study
mouse
nonhuman
priority journal
protein expression
skin fibroblast
smooth muscle contractility
stem cell niche
animal
dermis
genetics
human
muscle contraction
mutant mouse strain
physiology
regeneration
smooth muscle
stem cell niche
Aggrecans
Animals
Dermis
Hair Follicle
Humans
Mice
Mice, Mutant Strains
Muscle Contraction
Muscle, Smooth
Regeneration
Stem Cell Niche