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Loss of phosphatidylserine flippase beta-subunit Tmem30a in podocytes leads to albuminuria and glomerulosclerosis 期刊论文
DISEASE MODELS & MECHANISMS, 2021, 卷号: 14, 期号: 6
作者:  Liu, Wenjing;  Peng, Lei;  Tian, Wanli;  Li, Yi;  Zhang, Ping;  Sun, Kuanxiang;  Yang, Yeming;  Li, Xiao;  Li, Guisen;  Zhu, Xianjun
收藏  |  浏览/下载：31/0  |  提交时间：2022/04/28
ENDOPLASMIC-RETICULUM STRESS  FOCAL SEGMENTAL GLOMERULOSCLEROSIS  SUBCELLULAR-LOCALIZATION  VIABLE PODOCYTES  EPITHELIAL-CELLS  MESANGIAL CELL  CDC50 PROTEINS  MOUSE MODELS  EXPRESSION  NEPHROPATHY  
The phosphatidylserine flippase beta-subunit Tmem30a is essential for normal insulin maturation and secretion 期刊论文
MOLECULAR THERAPY, 2021, 卷号: 29, 期号: 9
作者:  Yang, Yeming;  Sun, Kuanxiang;  Liu, Wenjing;  Li, Xiao;  Tian, Wanli;  Shuai, Ping;  Zhu, Xianjun
收藏  |  浏览/下载：28/0  |  提交时间：2022/04/28
PANCREATIC BETA-CELLS  FATTY LIVER-DISEASE  TRANS-GOLGI NETWORK  PHOSPHOLIPID TRANSLOCATION  ENDOPLASMIC-RETICULUM  PLASMA-MEMBRANE  CDC50 PROTEINS  OBESITY  ATPASE  GENE  
Endoplasmic reticulum contact sites regulate the dynamics of membraneless organelles 期刊论文
, 2020, 卷号: 367, 期号: 6477
作者:  Lee J.E.;  Cathey P.I.;  Wu H.;  Parker R.;  Voeltz G.K.
收藏  |  浏览/下载：26/0  |  提交时间：2020/07/28
cell component  cell organelle  membrane  protein  Article  biogenesis  cell division  cell organelle  cell population  cell proliferation  cell structure  controlled study  cytoplasm  dimerization  endoplasmic reticulum  endoplasmic reticulum stress  endosome  fluorescence microscopy  human  human cell  membraneless organelle  mitochondrion  priority journal  ribonucleoprotein granule  RNA translation  stress granule  
Correlative three-dimensional super-resolution and block-face electron microscopy of whole vitreously frozen cells 期刊论文
, 2020, 卷号: 367, 期号: 6475
作者:  Hoffman D.P.;  Shtengel G.;  Xu C.S.;  Campbell K.R.;  Freeman M.;  Wang L.;  Milkie D.E.;  Pasolli H.A.;  Iyer N.;  Bogovic J.A.;  Stabley D.R.;  Shirinifard A.;  Pang S.;  Peale D.;  Schaefer K.;  Pomp W.;  Chang C.-L.;  Lippincott-Schwartz J.;  Kirchhausen T.;  Solecki D.J.;  Betzig E.;  Hess H.F.
收藏  |  浏览/下载：50/0  |  提交时间：2020/07/28
cell  compartmentalization  cryopreservation  electron microscopy  image resolution  protein  three-dimensional modeling  ultrastructure  article  chromatin  electron microscopy  endoplasmic reticulum  genetic transcription  human cell  mammal cell  nerve cell culture  protein domain  ultrastructure  whole cell  workflow  animal  cell adhesion  cells  Chlorocebus aethiops  cryoelectron microscopy  CV-1 cell line  fluorescence microscopy  freezing  HeLa cell line  human  mouse  procedures  three-dimensional imaging  tumor cell line  ultrastructure  Mammalia  Animals  Cell Adhesion  Cell Line, Tumor  Cells  Chlorocebus aethiops  COS Cells  Cryoelectron Microscopy  Freezing  HeLa Cells  Humans  Imaging, Three-Dimensional  Mice  Microscopy, Fluorescence  
Golgi-derived PI(4)P-containing vesicles drive late steps of mitochondrial division 期刊论文
, 2020, 卷号: 367, 期号: 6484
作者:  Nagashima S.;  Tábara L.-C.;  Tilokani L.;  Paupe V.;  Anand H.;  Pogson J.H.;  Zunino R.;  McBride H.M.;  Prudent J.
收藏  |  浏览/下载：36/0  |  提交时间：2020/07/28
adenosine diphosphate ribosylation factor 1  dynamin related protein 1  mitochondrial protein  phosphatidylinositol 4 kinase IIIbeta  phosphatidylinositol 4 phosphate  phosphatidylinositol kinase  unclassified drug  adenosine diphosphate ribosylation factor 1  ARF1 protein, human  DNM1L protein, human  dynamin  phosphatidylinositol 4-phosphate  phosphatidylinositol kinase  polyphosphoinositide  cell component  cell organelle  chemical compound  enzyme  enzyme activity  mitochondrion  protein  Article  controlled study  COS-7 cell line  endoplasmic reticulum  fibroblast  gene silencing  HeLa cell line  human  human cell  membrane microdomain  mitochondrial division  mitochondrial dynamics  mitochondrial scission  priority journal  protein localization  trans Golgi network  U2OS cell line  animal  cell line  Chlorocebus aethiops  CV-1 cell line  genetics  metabolism  mitochondrial membrane  mitochondrion  RNA interference  trans Golgi network  ultrastructure  Mammalia  1-Phosphatidylinositol 4-Kinase  ADP-Ribosylation Factor 1  Animals  Cell Line  Chlorocebus aethiops  COS Cells  Dynamins  Endoplasmic Reticulum  HeLa Cells  Humans  Membrane Microdomains  Mitochondria  Mitochondrial Dynamics  Mitochondrial Membranes  Phosphatidylinositol Phosphates  RNA Interference  trans-Golgi Network  
Endoplasmic reticulum-associated degradation regulates mitochondrial dynamics in brown adipocytes 期刊论文
, 2020, 卷号: 368, 期号: 6486
作者:  Zhou Z.;  Torres M.;  Sha H.;  Halbrook C.J.;  van den Bergh F.;  Reinert R.B.;  Yamada T.;  Wang S.;  Luo Y.;  Hunter A.H.;  Wang C.;  Sanderson T.H.;  Liu M.;  Taylor A.;  Sesaki H.;  Lyssiotis C.A.;  Wu J.;  Kersten S.;  Beard D.A.;  Qi L.
收藏  |  浏览/下载：44/0  |  提交时间：2020/07/28
Hrd1 protein  membrane protein  Sel1L protein  sigma opiate receptor  sigma receptor 1  ubiquitin protein ligase E3  unclassified drug  biodegradation  cell organelle  membrane  mitochondrion  physiology  protein  turnover  animal cell  Article  brown adipocyte  cell contact  controlled study  endoplasmic reticulum  endoplasmic reticulum associated degradation  megamitochondria  mitochondrial dynamics  mitochondrion  mouse  nonhuman  priority journal  protein metabolism  protein protein interaction  thermogenesis  three-dimensional imaging  Mus  
Four glial cells regulate ER stress resistance and longevity via neuropeptide signaling in C. Elegans 期刊论文
, 2020, 卷号: 367, 期号: 6476
作者:  Frakes A.E.;  Metcalf M.G.;  Tronnes S.U.;  Bar-Ziv R.;  Durieux J.;  Gildea H.K.;  Kandahari N.;  Monshietehadi S.;  Dillin A.
收藏  |  浏览/下载：22/0  |  提交时间：2020/07/28
neuropeptide  transcription factor  ATF-6 protein, C elegans  Caenorhabditis elegans protein  carrier protein  neuropeptide  protein aggregate  transcription factor  XBP-1 protein, C elegans  cell component  cell organelle  homeostasis  longevity  nematode  nervous system  peptide  protein  secretion  Article  astrocyte  Caenorhabditis elegans  cell activation  chronic stress  controlled study  endoplasmic reticulum stress  glia cell  lifespan  nonhuman  priority journal  protein aggregation  protein expression  protein secretion  signal transduction  unfolded protein response  animal  endoplasmic reticulum stress  genetics  glia  longevity  mutation  physiology  signal transduction  Animalia  Caenorhabditis elegans  Animals  Caenorhabditis elegans  Caenorhabditis elegans Proteins  Carrier Proteins  Endoplasmic Reticulum Stress  Longevity  Mutation  Neuroglia  Neuropeptides  Protein Aggregates  Signal Transduction  Transcription Factors  
Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex 期刊论文
, 2020, 卷号: 368, 期号: 6489
作者:  [无可用作者姓名]
收藏  |  浏览/下载：48/0  |  提交时间：2020/07/28
Hrd1 ubiquitin ligase complex  Hrd3 protein  membrane protein  polypeptide  rhomboid like Der1 protein  ubiquitin protein ligase  unclassified drug  Yos9 protein  biodegradation  cell component  electron microscopy  enzyme  molecular analysis  protein  ultrastructure  Article  binding site  carboxy terminal sequence  controlled study  cryoelectron microscopy  cytosol  endoplasmic reticulum  enzyme substrate  enzyme substrate complex  fungal strain  glycosylation  micelle  molecular dynamics  priority journal  protein cross linking  protein degradation  protein function  protein misfolding  protein structure  yeast