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Influence of low-temperature curing on the mechanical strength, hydration process, and microstructure of alkali-activated fly ash and ground granulated blast furnace slag mortar 期刊论文
CONSTRUCTION AND BUILDING MATERIALS, 2021, 卷号: 269
作者:  Wei, Xiaobin;  Li, Dongqing;  Ming, Feng;  Yang, Chengsong;  Chen, Lei;  Liu, Yuhang
收藏  |  浏览/下载：46/0  |  提交时间：2022/04/28
ELECTRICAL-RESISTIVITY MEASUREMENT  GEOPOLYMER CONCRETE  CHLORIDE PERMEABILITY  MERCURY POROSIMETRY  PORE STRUCTURE  CEMENT  SUPERPLASTICIZER  DURABILITY  BEHAVIOR  DESIGN  
Green perovskite light-emitting diodes with simultaneous high luminance and quantum efficiency through charge injection engineering 期刊论文
Science Bulletin, 2020, 卷号: 65, 期号: 21
作者:  Zhang T.;  Long M.;  Pan L.;  Ngai K.;  Qin M.;  Xie F.;  Lu X.;  Chen J.;  Xu J.
收藏  |  浏览/下载：45/0  |  提交时间：2021/09/01
Balanced charge injection  High luminance  Molecular doping  Perovskite LED  Structure design  
Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease 期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:  Dai W.;  Zhang B.;  Jiang X.-M.;  Su H.;  Li J.;  Zhao Y.;  Xie X.;  Jin Z.;  Peng J.;  Liu F.;  Li C.;  Li Y.;  Bai F.;  Wang H.;  Cheng X.;  Cen X.;  Hu S.;  Yang X.;  Wang J.;  Liu X.;  Xiao G.;  Jiang H.;  Rao Z.;  Zhang L.-K.;  Xu Y.;  Yang H.;  Liu H.
收藏  |  浏览/下载：50/0  |  提交时间：2020/07/28
aldehyde  antimicrobial activity  drug  enzyme activity  infectivity  inhibitor  reaction kinetics  viral disease  Coronavirus  SARS coronavirus  3C-like proteinase, Coronavirus  antivirus agent  cysteine proteinase  viral protein  animal  Betacoronavirus  chemical structure  chemistry  Chlorocebus aethiops  Coronavirus infection  dog  drug design  drug effect  enzyme active site  enzymology  female  human  male  mouse  pandemic  preclinical study  protein tertiary structure  Sprague Dawley rat  toxicity testing  Vero cell line  virus pneumonia  Animals  Antiviral Agents  Betacoronavirus  Catalytic Domain  Chlorocebus aethiops  Coronavirus Infections  Cysteine Endopeptidases  Dogs  Drug Design  Drug Evaluation, Preclinical  Female  Humans  Male  Mice  Molecular Structure  Pandemics  Pneumonia, Viral  Protein Structure, Tertiary  Rats, Sprague-Dawley  Toxicity Tests  Vero Cells  Viral Nonstructural Proteins  
A specialized forest carnivore navigates landscape-level disturbance: Canada lynx in spruce-beetle impacted forests 期刊论文
, 2020, 卷号: 475
作者:  Squires J.R.;  Holbrook J.D.;  Olson L.E.;  Ivan J.S.;  Ghormley R.W.;  Lawrence R.L.
收藏  |  浏览/下载：33/0  |  提交时间：2020/07/28
Managers  Timber  Availability design  Dendroctonus rufipennis  Forest carnivores  Forest structure  Functional response  Natural disturbance  Southern rocky mountains  Subalpine forests  Forestry  Abies lasiocarpa  Coleoptera  Dendroctonus rufipennis  Hexapoda  Lepus americanus  Lynx canadensis  Picea  Picea engelmannii  Scolytinae  
Forest management affects crane fly (Tipuloidea) community structure through changes in edaphic conditions 期刊论文
, 2020, 卷号: 457
作者:  Byriel D.B.;  Schmidt I.K.;  Justesen M.J.;  Pape T.;  Hansen A.K.;  Riis-Nielsen T.;  Kepfer-Rojas S.
收藏  |  浏览/下载：38/0  |  提交时间：2020/07/28
Conservation  Cranes  Soil moisture  Community structures  Edaphic conditions  Environmental variables  Forest conservation  Geographic location  Saproxylic species  Species composition  Unmanaged forest  Forestry  community composition  community structure  experimental design  fly  forest management  forest soil  saproxylic organism  soil fauna  species richness  Conservation  Cranes  Forest Management  Forestry  Moisture  Ph  Sites  Soil  Denmark  Tipulidae  Tipuloidea  
Combining conservation value with conservation filters to guide forest management for avian biodiversity 期刊论文
, 2020, 卷号: 466
作者:  Crosby A.D.;  Porter W.F.;  Roloff G.J.;  Walters M.B.;  Donovan M.L.
收藏  |  浏览/下载：39/0  |  提交时间：2020/07/28
Biodiversity  Birds  Conservation  Decision making  Bird community compositions  Conservation strategies  Conservation values  Management decisions  Novel applications  Relative contribution  Structural complexity  Sustainable forest management  Forestry  basal area  biodiversity  bird  community structure  coniferous tree  conservation planning  design  forest management  management practice  species diversity  species richness  strategic approach  sustainability  Biodiversity  Birds  Conservation  Decision Making  Forestry  Sustainable Forest Management  Michigan  United States  Upper Peninsula  Aves  Coniferophyta  
De novo design of protein logic gates 期刊论文
, 2020, 卷号: 368, 期号: 6486
作者:  Chen Z.;  Kibler R.D.;  Hunt A.;  Busch F.;  Pearl J.;  Jia M.;  VanAernum Z.L.;  Wicky B.I.M.;  Dods G.;  Liao H.;  Wilken M.S.;  Ciarlo C.;  Green S.;  El-Samad H.;  Stamatoyannopoulos J.;  Wysocki V.H.;  Jewett M.C.;  Boyken S.E.;  Baker D.
收藏  |  浏览/下载：38/0  |  提交时间：2020/07/28
cell  design method  gene expression  genetic analysis  protein  activation domain  Article  binding affinity  circular dichroism  controlled study  de novo design  design  DNA binding motif  enzyme activity  genetic transcription  human  human cell  hydrogen bond  hydrophobicity  mass spectrometry  native mass spectrometry  nonhuman  priority journal  protein protein interaction  protein structure  RNA translation  stoichiometry  thermodynamics  two hybrid system  X ray crystallography  chemistry  genetics  logic  metabolism  protein analysis  protein engineering  protein processing  synthetic biology  T lymphocyte  yeast  HAVCR2 protein, human  hepatitis A virus cellular receptor 2  Hepatitis A Virus Cellular Receptor 2  Humans  Logic  Mass Spectrometry  Protein Engineering  Protein Interaction Maps  Protein Processing, Post-Translational  Synthetic Biology  T-Lymphocytes  Transcription, Genetic  Yeasts  
Molecular mechanism of biased signaling in a prototypical G protein-coupled receptor 期刊论文
, 2020, 卷号: 367, 期号: 6480
作者:  Suomivuori C.-M.;  Latorraca N.R.;  Wingler L.M.;  Eismann S.;  King M.C.;  Kleinhenz A.L.W.;  Skiba M.A.;  Staus D.P.;  Kruse A.C.;  Lefkowitz R.J.;  Dror R.O.
收藏  |  浏览/下载：30/0  |  提交时间：2020/07/28
angiotensin 1 receptor  beta arrestin 1  beta arrestin 2  G protein coupled receptor  rhodopsin  chemical binding  design method  ligand  molecular analysis  protein  signaling  allosterism  Article  carboxy terminal sequence  conformational transition  controlled study  crystal structure  human  ligand binding  molecular dynamics  priority journal  protein conformation  signal transduction  structural model  
Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation 期刊论文
, 2020, 卷号: 368, 期号: 6489
作者:  Gilan O.;  Rioja I.;  Knezevic K.;  Bell M.J.;  Yeung M.M.;  Harker N.R.;  Lam E.Y.N.;  Chung C.;  Bamborough P.;  Petretich M.;  Urh M.;  Atkinson S.J.;  Bassil A.K.;  Roberts E.J.;  Vassiliadis D.;  Burr M.L.;  Preston A.G.S.;  Wellaway C.;  Werner T.;  Gray J.R.;  Michon A.-M.;  Gobbetti T.;  Kumar V.;  Soden P.E.;  Haynes A.;  Vappiani J.;  Tough D.F.;  Taylor S.;  Dawson S.-J.;  Bantscheff M.;  Lindon M.;  Drewes G.;  Demont E.H.;  Daniels D.L.;  Grandi P.;  Prinjha R.K.;  Dawson M.A.
收藏  |  浏览/下载：54/0  |  提交时间：2020/07/28
7 (3,5 dimethyl 4 isoxazolyl) 1,3 dihydro 8 methoxy 1 [1 (2 pyridinyl)ethyl] 2h imidazo[4,5 c]quinolin 2 one  apremilast  bromodomain and extraterminal domain protein 1  bromodomain and extraterminal domain protein 2  bromodomain inhibitor  gsk 046  gsk 620  gsk 778  transcription factor  unclassified drug  cancer  drug  gene expression  immune response  inhibitor  physiological response  acute myeloid leukemia  animal experiment  animal model  animal tissue  antibody response  antineoplastic activity  antiproliferative activity  apoptosis  Article  binding affinity  controlled study  crystal structure  drug design  drug efficacy  drug protein binding  drug selectivity  drug specificity  drug structure  drug targeting  gene expression  high throughput screening  human  human cell  IC50  immunomodulation  in vivo study  inflammation  K-562 cell line  malignant neoplasm  MDA-MB-453 cell line  MOLM-13 cell line  mouse  nonhuman  priority journal  psoriasis  
Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved a-ketoamide inhibitors 期刊论文
, 2020, 卷号: 368, 期号: 6489
作者:  Zhang L.;  Lin D.;  Sun X.;  Curth U.;  Drosten C.;  Sauerhering L.;  Becker S.;  Rox K.;  Hilgenfeld R.
收藏  |  浏览/下载：45/0  |  提交时间：2020/07/28
alanine  alpha ketoamide inhibitor  antivirus agent  isoleucine  leucine  proteinase  Severe acute respiratory syndrome coronavirus 2 main protease  threonine  unclassified drug  crystal structure  drug  enzyme  enzyme activity  inhibitor  reaction kinetics  amino acid sequence  animal cell  animal experiment  animal tissue  antiviral activity  Article  catalysis  catalytic efficiency  controlled study  crystal structure  dimerization  dissociation constant  drug clearance  drug design  drug distribution  drug half life  drug potency  drug protein binding  drug solubility  drug structure  EC50  enzyme inhibition  human  human cell  hydrogen bond  hydrophobicity  IC50  maximum concentration  mean residence time  metabolic stability  mouse  nonhuman  priority journal  protein structure  RNA replication  SARS coronavirus  Severe acute respiratory syndrome coronavirus 2  viral tropism  virus inhibition  Coronavirus  SARS coronavirus