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Maternal gut microbiota in pregnancy influences offspring metabolic phenotype in mice 期刊论文
, 2020, 卷号: 367, 期号: 6481
作者:  Kimura I.;  Miyamoto J.;  Ohue-Kitano R.;  Watanabe K.;  Yamada T.;  Onuki M.;  Aoki R.;  Isobe Y.;  Kashihara D.;  Inoue D.;  Inaba A.;  Takamura Y.;  Taira S.;  Kumaki S.;  Watanabe M.;  Ito M.;  Nakagawa F.;  Irie J.;  Kakuta H.;  Shinohara M.;  Iwatsuki K.;  Tsujimoto G.;  Ohno H.;  Arita M.;  Itoh H.;  Hase K.
收藏  |  浏览/下载:48/0  |  提交时间:2020/07/28
G protein coupled receptor  G protein coupled receptor 41  G protein coupled receptor 43  glucagon like peptide 1  short chain fatty acid  unclassified drug  disease incidence  experimental study  female  microbial community  phenotype  pregnancy  rodent  adult  animal cell  animal experiment  animal model  animal tissue  Article  C57BL 6 mouse  cell differentiation  controlled study  developmental stage  diet composition  diet supplementation  dietary exposure  disease exacerbation  disease predisposition  embryo  embryo development  energy metabolism  enteroendocrine cell  female  fiber intake  germfree animal  glucose intolerance  high risk pregnancy  hyperglycemia  Institute for Cancer Research mouse  insulin metabolism  intestine flora  lipid diet  low fiber diet  male  maternal nutrition  metabolic syndrome X  mouse  newborn  nonhuman  obesity  pancreas islet beta cell  phenotype  pregnancy  prenatal development  priority journal  progeny  protein expression  risk reduction  Mus  
Interleukin-13 drives metabolic conditioning of muscle to endurance exercise 期刊论文
, 2020, 卷号: 368, 期号: 6490
作者:  Knudsen N.H.;  Stanya K.J.;  Hyde A.L.;  Chalom M.M.;  Alexander R.K.;  Liou Y.-H.;  Starost K.A.;  Gangl M.R.;  Jacobi D.;  Liu S.;  Sopariwala D.H.;  Fonseca-Pereira D.;  Li J.;  Hu F.B.;  Garrett W.S.;  Narkar V.A.;  Ortlund E.A.;  Kim J.H.;  Paton C.M.;  Cooper J.A.;  Lee C.-H.
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glucose  interleukin 13  interleukin 13 receptor alpha1  interleukin 6  STAT3 protein  fatty acid  glycogen  interleukin 13  interleukin 13 receptor alpha1  STAT3 protein  Stat3 protein, mouse  fatty acid  metabolism  muscle  oxidation  physiological response  protein  respiration  aerobic exercise  animal cell  animal experiment  animal tissue  Article  C2C12 cell line  cohort analysis  controlled study  endurance training  energy metabolism  ex vivo study  exercise intensity  female  gastrocnemius muscle  glucose tolerance  human  in vitro study  male  mitochondrial biogenesis  mitochondrial dynamics  mitochondrial respiration  mouse  muscle metabolism  muscle mitochondrion  nonhuman  obesity  priority journal  protein blood level  protein expression  running  sedentary lifestyle  signal transduction  treadmill exercise  adaptation  animal  blood  C57BL mouse  cell line  endurance  genetics  glucose blood level  immunology  knockout mouse  metabolism  myoblast  oxidation reduction reaction  skeletal muscle  Mus  Adaptation, Physiological  Animals  Blood Glucose  Cell Line  Fatty Acids  Female  Glycogen  Humans  Interleukin-13  Interleukin-13 Receptor alpha1 Subunit  Male  Mice  Mice, Inbred C57BL  Mice, Knockout  Mitochondria, Muscle  Muscle, Skeletal  Myoblasts  Oxidation-Reduction  Physical Conditioning, Animal  Physical Endurance  Running  STAT3 Transcription Factor  
An AMPK–caspase-6 axis controls liver damage in nonalcoholic steatohepatitis 期刊论文
, 2020, 卷号: 367, 期号: 6478
作者:  Zhao P.;  Sun X.;  Chaggan C.;  Liao Z.;  Wong K.I.;  He F.;  Singh S.;  Loomba R.;  Karin M.;  Witztum J.L.;  Saltiel A.R.
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6,7 dihydro 4 hydroxy 3 (2' hydroxy 1,1' biphenyl 4 yl) 6 oxothieno[2,3 b]pyridine 5 carbonitrile  adenosine phosphate  caspase 3  caspase 6  caspase 7  cytochrome c  hydroxymethylglutaryl coenzyme A reductase kinase  matrix metalloproteinase  apoptosis  cytochrome  enzyme  enzyme activity  inhibition  protein  rodent  AMPK signaling  animal experiment  animal model  animal tissue  apoptosis  Article  C57BL 6 mouse  cell death  controlled study  drug mechanism  enzyme activation  enzyme activity  enzyme inhibition  enzyme phosphorylation  enzyme repression  gene knockout  human  human cell  human tissue  liver cell  liver fibrosis  liver injury  male  mouse  nonalcoholic steatohepatitis  nonhuman  priority journal  protein cleavage  protein secretion  
Microglia mediate forgetting via complement-dependent synaptic elimination 期刊论文
, 2020, 卷号: 367, 期号: 6478
作者:  Wang C.;  Yue H.;  Hu Z.;  Shen Y.;  Ma J.;  Li J.;  Wang X.-D.;  Wang L.;  Sun B.;  Shi P.;  Wang L.;  Gu Y.
收藏  |  浏览/下载:34/0  |  提交时间:2020/07/28
complement  complement component C1q  complement component C3  complement receptor  decay accelerating factor  adult  cell  inhibition  memory  nervous system  adult  aging  animal cell  animal experiment  Article  C57BL 6 mouse  cognition  controlled study  functional dissociation  hippocampus  memory  memory consolidation  microglia  mouse  nerve cell inhibition  nerve cell plasticity  nervous system development  nonhuman  phagocytosis  priority journal  synaptic inhibition  Mus