CCPortal

浏览/检索结果: 共6条,第1-6条 帮助

限定条件        
已选(0)清除 条数/页:   排序方式:
The Rhinolophus affinis bat ACE2 and multiple animal orthologs are functional receptors for bat coronavirus RaTG13 and SARS-CoV-2 期刊论文
Science Bulletin, 2021, 卷号: 66, 期号: 12
作者:  Li P.;  Guo R.;  Liu Y.;  Zhang Y.;  Hu J.;  Ou X.;  Mi D.;  Chen T.;  Mu Z.;  Han Y.;  Chen Z.;  Cui Z.;  Zhang L.;  Wang X.;  Wu Z.;  Wang J.;  Jin Q.;  Qian Z.
收藏  |  浏览/下载:33/0  |  提交时间:2021/09/01
Bat coronavirus RaTG13  Coronavirus entry  Host susceptibility  Rhinolophus affinis bat ACE2  SARS-CoV-2  Spike protein  
Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease 期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:  Dai W.;  Zhang B.;  Jiang X.-M.;  Su H.;  Li J.;  Zhao Y.;  Xie X.;  Jin Z.;  Peng J.;  Liu F.;  Li C.;  Li Y.;  Bai F.;  Wang H.;  Cheng X.;  Cen X.;  Hu S.;  Yang X.;  Wang J.;  Liu X.;  Xiao G.;  Jiang H.;  Rao Z.;  Zhang L.-K.;  Xu Y.;  Yang H.;  Liu H.
收藏  |  浏览/下载:36/0  |  提交时间:2020/07/28
aldehyde  antimicrobial activity  drug  enzyme activity  infectivity  inhibitor  reaction kinetics  viral disease  Coronavirus  SARS coronavirus  3C-like proteinase, Coronavirus  antivirus agent  cysteine proteinase  viral protein  animal  Betacoronavirus  chemical structure  chemistry  Chlorocebus aethiops  Coronavirus infection  dog  drug design  drug effect  enzyme active site  enzymology  female  human  male  mouse  pandemic  preclinical study  protein tertiary structure  Sprague Dawley rat  toxicity testing  Vero cell line  virus pneumonia  Animals  Antiviral Agents  Betacoronavirus  Catalytic Domain  Chlorocebus aethiops  Coronavirus Infections  Cysteine Endopeptidases  Dogs  Drug Design  Drug Evaluation, Preclinical  Female  Humans  Male  Mice  Molecular Structure  Pandemics  Pneumonia, Viral  Protein Structure, Tertiary  Rats, Sprague-Dawley  Toxicity Tests  Vero Cells  Viral Nonstructural Proteins  
Pulmonary surfactant-biomimetic nanoparticles potentiate heterosubtypic influenza immunity 期刊论文
, 2020, 卷号: 367, 期号: 6480
作者:  Wang J.;  Li P.;  Yu Y.;  Fu Y.;  Jiang H.;  Lu M.;  Sun Z.;  Jiang S.;  Lu L.;  Wu M.X.
收藏  |  浏览/下载:33/0  |  提交时间:2020/07/28
2',3' cyclic guanosine monophosphate adenosine monophosphate  influenza vaccine  interferon  nanoparticle  pulmonary surfactant biomimetic nanoparticle  purine nucleotide  surfactant protein A  surfactant protein D  unclassified drug  cell  drug resistance  immune response  immunity  induced response  influenza  nanoparticle  rodent  surfactant  vaccine  animal cell  animal experiment  animal model  animal tissue  Article  CD8+ T lymphocyte  cellular immunity  controlled study  cross protection  cytokine response  drug efficacy  drug safety  drug synthesis  female  human  humoral immunity  hydrophilicity  immune response  immunopathology  immunosurveillance  influenza  innate immunity  lung alveolus epithelium cell  lung alveolus macrophage  mouse  Mustela putorius furo  nanoencapsulation  nonhuman  priority journal  Mus  Mustela  
An atlas of the protein-coding genes in the human, pig, and mouse brain 期刊论文
, 2020, 卷号: 367, 期号: 6482
作者:  Sjöstedt E.;  Zhong W.;  Fagerberg L.;  Karlsson M.;  Mitsios N.;  Adori C.;  Oksvold P.;  Edfors F.;  Limiszewska A.;  Hikmet F.;  Huang J.;  Du Y.;  Lin L.;  Dong Z.;  Yang L.;  Liu X.;  Jiang H.;  Xu X.;  Wang J.;  Yang H.;  Bolund L.;  Mardinoglu A.;  Zhang C.;  von Feilitzen K.;  Lindskog C.;  Pontén F.;  Luo Y.;  Hökfelt T.;  Uhlén M.;  Mulder J.
收藏  |  浏览/下载:27/0  |  提交时间:2020/07/28
nerve protein  transcriptome  animal  antibody specificity  book  brain  C57BL mouse  comparative study  female  gene expression regulation  genetics  human  information processing  male  mouse  physiology  pig  species difference  Animals  Atlases as Topic  Brain  Datasets as Topic  Female  Gene Expression Regulation  Humans  Male  Mice  Mice, Inbred C57BL  Nerve Tissue Proteins  Organ Specificity  Species Specificity  Swine  Transcriptome  
An atlas of the protein-coding genes in the human, pig, and mouse brain 期刊论文
, 2020, 卷号: 367, 期号: 6482
作者:  Sjöstedt E.;  Zhong W.;  Fagerberg L.;  Karlsson M.;  Mitsios N.;  Adori C.;  Oksvold P.;  Edfors F.;  Limiszewska A.;  Hikmet F.;  Huang J.;  Du Y.;  Lin L.;  Dong Z.;  Yang L.;  Liu X.;  Jiang H.;  Xu X.;  Wang J.;  Yang H.;  Bolund L.;  Mardinoglu A.;  Zhang C.;  Von Feilitzen K.;  Lindskog C.;  Pontén F.;  Luo Y.;  Hökfelt T.;  Uhlén M.;  Mulder J.
收藏  |  浏览/下载:35/0  |  提交时间:2020/07/28
G protein coupled receptor  neurotransmitter  atlas  brain  gene  gene expression  pig  protein  Article  astrocyte  cerebellum  gene expression level  gene expression profiling  gene mapping  genetic code  genome-wide association study  genomics  human  hypothalamus  in situ hybridization  microglia  nerve cell  nonhuman  oligodendroglia  pig  priority journal  species comparison  tissue specificity  transcriptomics  Mammalia  Suidae  
Enhanced sustainable green revolution yield via nitrogen-responsive chromatin modulation in rice 期刊论文
, 2020, 卷号: 367, 期号: 6478
作者:  Wu K.;  Wang S.;  Song W.;  Zhang J.;  Wang Y.;  Liu Q.;  Yu J.;  Ye Y.;  Li S.;  Chen J.;  Zhao Y.;  Wang J.;  Wu X.;  Wang M.;  Zhang Y.;  Liu B.;  Wu Y.;  Harberd N.P.;  Fu X.
收藏  |  浏览/下载:35/0  |  提交时间:2020/07/28
DELLA protein  gibberellin  gibberellin insensitive dwarf1  histone H3  polycomb repressive complex 2  receptor  transcription factor  unclassified drug  alternative agriculture  chromosome  gene expression  genetic engineering  green revolution  inhibition  molecular analysis  nitrogen  nutrient use efficiency  protein  rice  agriculture  allele  Article  chromatin immunoprecipitation  controlled study  D14 gene  gene mutation  genetic screening  genetic transcription  grain yield  green revolution  histone modification  modulation  ngr5 gene  nitrogen availability  nitrogen responsive chromatin modulation  nonhuman  OsSPL14 gene  plant gene  polymerase chain reaction  priority journal  protein protein interaction  rice  RNA sequencing  varietas