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Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir 期刊论文
, 2020, 卷号: 368, 期号: 6498
作者:  Yin W.;  Mao C.;  Luan X.;  Shen D.-D.;  Shen Q.;  Su H.;  Wang X.;  Zhou F.;  Zhao W.;  Gao M.;  Chang S.;  Xie Y.-C.;  Tian G.;  Jiang H.-W.;  Tao S.-C.;  Shen J.;  Jiang Y.;  Jiang H.;  Xu Y.;  Zhang S.;  Zhang Y.;  Xu H.E.
收藏  |  浏览/下载：131/0  |  提交时间：2020/07/28
adenosine phosphate  alanine  antivirus agent  enzyme inhibitor  multiprotein complex  NSP7 protein, SARS-CoV-2  NSP8 protein, SARS-CoV-2  remdesivir  RNA directed RNA polymerase  RNA-dependent RNA polymerase, coronavirus  viral protein  virus RNA  Betacoronavirus  chemistry  cryoelectron microscopy  drug effect  enzyme active site  enzymology  metabolism  molecular model  physiology  protein conformation  virus replication  Adenosine Monophosphate  Alanine  Antiviral Agents  Betacoronavirus  Catalytic Domain  Cryoelectron Microscopy  Enzyme Inhibitors  Models, Molecular  Multiprotein Complexes  Protein Conformation  RNA Replicase  RNA, Viral  Viral Nonstructural Proteins  Virus Replication  
Feasibility of blood testing combined with PET-CT to screen for cancer and guide intervention 期刊论文
, 2020, 卷号: 369, 期号: 6499
作者:  Lennon A.M.;  Buchanan A.H.;  Kinde I.;  Warren A.;  Honushefsky A.;  Cohain A.T.;  Ledbetter D.H.;  Sanfilippo F.;  Sheridan K.;  Rosica D.;  Adonizio C.S.;  Hwang H.J.;  Lahouel K.;  Cohen J.D.;  Douville C.;  Patel A.A.;  Hagmann L.N.;  Rolston D.D.;  Malani N.;  Zhou S.;  Bettegowda C.;  Diehl D.L.;  Urban B.;  Still C.D.;  Kann L.;  Woods J.I.;  Salvati Z.M.;  Vadakara J.;  Leeming R.;  Bhattacharya P.;  Walter C.;  Parker A.;  Lengauer C.;  Klein A.;  Tomasetti C.;  Fishman E.K.;  Hruban R.H.;  Kinzler K.W.;  Vogelstein B.;  Papadopoulos N.
收藏  |  浏览/下载：30/0  |  提交时间：2020/07/28
aged  blood  blood examination  cohort analysis  diagnostic imaging  early cancer diagnosis  female  human  mass screening  neoplasm  positron emission tomography-computed tomography  procedures  Aged  Cohort Studies  Early Detection of Cancer  Female  Hematologic Tests  Humans  Mass Screening  Neoplasms  Positron Emission Tomography Computed Tomography