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| Structure and selectivity engineering of the M1 muscarinic receptor toxin complex 期刊论文 , 2020, 卷号: 369, 期号: 6500 作者: Maeda S.; Xu J.; N Kadji F.M.; Clark M.J.; Zhao J.; Tsutsumi N.; Aoki J.; Sunahara R.K.; Inoue A.; Garcia K.C.; Kobilka B.K. 收藏  |  浏览/下载:45/0  |  提交时间:2020/07/28 atropine m1-toxin muscarinic M1 receptor muscarinic receptor blocking agent snake venom animal chemistry genetic engineering genetics protein conformation Sf9 cell line X ray crystallography Animals Atropine Crystallography, X-Ray Elapid Venoms Genetic Engineering Muscarinic Antagonists Protein Conformation Receptor, Muscarinic M1 Sf9 Cells |
| A phage-encoded anti-CRISPR enables complete evasion of type VI-A CRISPR-Cas immunity 期刊论文 , 2020, 卷号: 369, 期号: 6499 作者: Meeske A.J.; Jia N.; Cassel A.K.; Kozlova A.; Liao J.; Wiedmann M.; Patel D.J.; Marraffini L.A. 收藏  |  浏览/下载:33/0  |  提交时间:2020/07/28 CRISPR associated protein endonuclease guide RNA viral protein virus RNA bacteriophage clustered regularly interspaced short palindromic repeat CRISPR Cas system DNA cleavage genetics Listeria metabolism RNA stability virology Bacteriophages Clustered Regularly Interspaced Short Palindromic Repeats CRISPR-Associated Proteins CRISPR-Cas Systems DNA Cleavage Endonucleases Listeria RNA Stability RNA, Guide RNA, Viral Viral Proteins |
| How to build a more open justice system 期刊论文 , 2020, 卷号: 369, 期号: 6500 作者: Pah A.R.; Schwartz D.L.; Sanga S.; Clopton Z.D.; DiCola P.; Mersey R.D.; Alexander C.S.; Hammond K.J.; Amaral L.A.N. 收藏  |  浏览/下载:18/0  |  提交时间:2020/07/28 |
| Pervasive functional translation of noncanonical human open reading frames 期刊论文 , 2020, 卷号: 367, 期号: 6482 作者: Chen J.; Brunner A.-D.; Cogan J.Z.; Nuñez J.K.; Fields A.P.; Adamson B.; Itzhak D.N.; Li J.Y.; Mann M.; Leonetti M.D.; Weissman J.S. 收藏  |  浏览/下载:24/0  |  提交时间:2020/07/28 messenger RNA peptide transcriptome CRISPR Cas system genetics human metabolism open reading frame operon protein synthesis ribosome CRISPR-Cas Systems Humans Open Reading Frames Operon Peptides Protein Biosynthesis Ribosomes RNA, Messenger Transcriptome |
| Population genetics of the coral Acropora millepora: Toward genomic prediction of bleaching 期刊论文 , 2020, 卷号: 369, 期号: 6501 作者: Fuller Z.L.; Mocellin V.J.L.; Morris L.A.; Cantin N.; Shepherd J.; Sarre L.; Peng J.; Liao Y.; Pickrell J.; Andolfatto P.; Matz M.; Bay L.K.; Przeworski M. 收藏  |  浏览/下载:30/0  |  提交时间:2020/07/28 |
| Tumor-initiating cells establish an IL-33-TGF-β niche signaling loop to promote cancer progression 期刊论文 , 2020, 卷号: 369, 期号: 6501 作者: Taniguchi S.; Elhance A.; Van Duzer A.; Kumar S.; Leitenberger J.J.; Oshimori N. 收藏  |  浏览/下载:26/0  |  提交时间:2020/07/28 |
| Aging immunity may exacerbate COVID-19 期刊论文 , 2020, 卷号: 369, 期号: 6501 作者: Akbar A.N.; Gilroy D.W. 收藏  |  浏览/下载:1/0  |  提交时间:2020/07/28 |
| Arctic-adapted dogs emerged at the Pleistocene-Holocene transition 期刊论文 , 2020, 卷号: 368, 期号: 6498 作者: Sinding M.-H.S.; Gopalakrishnan S.; Ramos-Madrigal J.; de Manuel M.; Pitulko V.V.; Kuderna L.; Feuerborn T.R.; Frantz L.A.F.; Vieira F.G.; Niemann J.; Samaniego Castruita J.A.; Carøe C.; Andersen-Ranberg E.U.; Jordan P.D.; Pavlova E.Y.; Nikolskiy P.A.; Kasparov A.K.; Ivanova V.V.; Willerslev E.; Skoglund P.; Fredholm M.; Wennerberg S.E.; Heide-Jørgensen M.P.; Dietz R.; Sonne C.; Meldgaard M.; Dalén L.; Larson G.; Petersen B.; Sicheritz-Pontén T.; Bachmann L.; Wiig Ø.; Marques-Bonet T.; Hansen A.J.; Gilbert M.T.P. 收藏  |  浏览/下载:39/0  |  提交时间:2020/07/28 adult animal experiment Arctic article attention gene flow genetic similarity Greenland haplotype Holocene nonhuman Pleistocene Russian Federation sled dog wolf |
| A multiplanet system of super-Earths orbiting the brightest red dwarf star GJ 887 期刊论文 , 2020, 卷号: 368, 期号: 6498 作者: Jeffers S.V.; Dreizler S.; Barnes J.R.; Haswell C.A.; Nelson R.P.; Rodríguez E.; López-González M.J.; Morales N.; Luque R.; Zechmeister M.; Vogt S.S.; Jenkins J.S.; Palle E.; Berdi Ñas Z.M.; Coleman G.A.L.; Díaz M.R.; Ribas I.; Jones H.R.A.; Butler R.P.; Tinney C.G.; Bailey J.; Carter B.D.; O'Toole S.; Wittenmyer R.A.; Crane J.D.; Feng F.; Shectman S.A.; Teske J.; Reiners A.; Amado P.J.; Anglada-Escudé G. 收藏  |  浏览/下载:29/0  |  提交时间:2020/07/28 |
| Mechanisms of OCT4-SOX2 motif readout on nucleosomes 期刊论文 , 2020, 卷号: 368, 期号: 6498 作者: Michael A.K.; Grand R.S.; Isbel L.; Cavadini S.; Kozicka Z.; Kempf G.; Bunker R.D.; Schenk A.D.; Graff-Meyer A.; Pathare G.R.; Weiss J.; Matsumoto S.; Burger L.; Schübeler D.; Thomä N.H. 收藏  |  浏览/下载:9/0  |  提交时间:2020/07/28 |