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Berberine reverses multidrug resistance in Candida albicans by hijacking the drug efflux pump Mdr1p 期刊论文
Science Bulletin, 2021
作者:  Tong Y.;  Zhang J.;  Sun N.;  Wang X.-M.;  Wei Q.;  Zhang Y.;  Huang R.;  Pu Y.;  Dai H.;  Ren B.;  Pei G.;  Song F.;  Zhu G.;  Wang X.;  Xia X.;  Chen X.;  Jiang L.;  Wang S.;  Ouyang L.;  Xie N.;  Zhang B.;  Jiang Y.;  Liu X.;  Calderone R.;  Bai F.;  Zhang L.;  Alterovitz G.
收藏  |  浏览/下载:43/0  |  提交时间:2021/09/01
Berberine  Candida albicans  Drug excretion transporter  Mitochondria  Multidrug-resistance  
Crystal structure of SARS-CoV-2 main protease in complex with the natural product inhibitor shikonin illuminates a unique binding mode 期刊论文
Science Bulletin, 2021, 卷号: 66, 期号: 7
作者:  Li J.;  Zhou X.;  Zhang Y.;  Zhong F.;  Lin C.;  McCormick P.J.;  Jiang F.;  Luo J.;  Zhou H.;  Wang Q.;  Fu Y.;  Duan J.;  Zhang J.
收藏  |  浏览/下载:31/0  |  提交时间:2021/09/01
Schizophrenia risk-gene Crmp2 deficiency causes precocious critical period plasticity and deteriorated binocular vision 期刊论文
Science Bulletin, 2021
作者:  Zhang Y.;  Yao L.;  Li X.;  Meng M.;  Shang Z.;  Wang Q.;  Xiao J.;  Gu X.;  Xu Z.;  Zhang X.
收藏  |  浏览/下载:32/0  |  提交时间:2021/09/01
Binocular depth perception  Collapsin response mediator protein-2 (CRMP2)  Critical period plasticity  Excitation-inhibition balance  Primary visual cortex  Schizophrenia  
The Rhinolophus affinis bat ACE2 and multiple animal orthologs are functional receptors for bat coronavirus RaTG13 and SARS-CoV-2 期刊论文
Science Bulletin, 2021, 卷号: 66, 期号: 12
作者:  Li P.;  Guo R.;  Liu Y.;  Zhang Y.;  Hu J.;  Ou X.;  Mi D.;  Chen T.;  Mu Z.;  Han Y.;  Chen Z.;  Cui Z.;  Zhang L.;  Wang X.;  Wu Z.;  Wang J.;  Jin Q.;  Qian Z.
收藏  |  浏览/下载:32/0  |  提交时间:2021/09/01
Bat coronavirus RaTG13  Coronavirus entry  Host susceptibility  Rhinolophus affinis bat ACE2  SARS-CoV-2  Spike protein  
SARS-CoV-2 nucleocapsid protein phase separates with G3BPs to disassemble stress granules and facilitate viral production 期刊论文
Science Bulletin, 2021, 卷号: 66, 期号: 12
作者:  Luo L.;  Li Z.;  Zhao T.;  Ju X.;  Ma P.;  Jin B.;  Zhou Y.;  He S.;  Huang J.;  Xu X.;  Zou Y.;  Li P.;  Liang A.;  Liu J.;  Chi T.;  Huang X.;  Ding Q.;  Jin Z.;  Huang C.;  Zhang Y.
收藏  |  浏览/下载:31/0  |  提交时间:2021/09/01
G3BP  Liquid-liquid phase separation  Nucleocapsid protein  SARS-CoV-2  Stress granules  Viral production  
Warming-driven migration of core microbiota indicates soil property changes at continental scale 期刊论文
Science Bulletin, 2021
作者:  Wang S.;  Bao X.;  Feng K.;  Deng Y.;  Zhou W.;  Shao P.;  Zheng T.;  Yao F.;  Yang S.;  Liu S.;  Shi R.;  Bai Z.;  Xie H.;  Yu J.;  Zhang Y.;  Zhang Y.;  Sha L.;  Song Q.;  Liu Y.;  Zhou J.;  Zhang Y.;  Li H.;  Wang Q.;  Han X.;  Zhu Y.;  Liang C.
收藏  |  浏览/下载:34/0  |  提交时间:2021/09/01
Climate change  Climate projection  Latitudinal pattern  Microbial biogeography  
Photocatalytic conversion of CO to fuels with water by B-doped graphene/g-C3N4 heterostructure 期刊论文
Science Bulletin, 2021, 卷号: 66, 期号: 12
作者:  Shi L.;  Zhou Z.;  Zhang Y.;  Ling C.;  Li Q.;  Wang J.
收藏  |  浏览/下载:17/0  |  提交时间:2021/09/01
2D heterostructure  First-principles calculations  Fischer-Tropsch synthesis  Photocatalyst  
Chiglitazar monotherapy with sitagliptin as an active comparator in patients with type 2 diabetes: a randomized, double-blind, phase 3 trial (CMAS) 期刊论文
Science Bulletin, 2021, 卷号: 66, 期号: 15
作者:  Jia W.;  Ma J.;  Miao H.;  Wang C.;  Wang X.;  Li Q.;  Lu W.;  Yang J.;  Zhang L.;  Yang J.;  Wang G.;  Zhang X.;  Zhang M.;  Sun L.;  Yu X.;  Du J.;  Shi B.;  Xiao C.;  Zhu D.;  Liu H.;  Zhong L.;  Xu C.;  Xu Q.;  Liang G.;  Zhang Y.;  Li G.;  Gu M.;  Liu J.;  Yuan G.;  Yan Z.;  Yan D.;  Ye S.;  Zhang F.;  Ning Z.;  Cao H.;  Pan D.;  Yao H.;  Lu X.;  Ji L.
收藏  |  浏览/下载:39/0  |  提交时间:2021/09/01
Chiglitazar  Glycemic control  Insulin resistance  PPAR pan-agonist  Type 2 diabetes  
A TOP6BL mutation abolishes meiotic DNA double-strand break formation and causes human infertility 期刊论文
Science Bulletin, 2020, 卷号: 65, 期号: 24
作者:  Jiao Y.;  Fan S.;  Jabeen N.;  Zhang H.;  Khan R.;  Murtaza G.;  Jiang H.;  Ali A.;  Li Y.;  Bao J.;  Zhang B.;  Xu J.;  Xu B.;  Hussain H.M.J.;  Zaman Q.;  Khan I.;  Bukhari I.;  Iqbal F.;  Yousaf A.;  Dil S.;  Khan M.;  Ahmad N.;  Ma H.;  Jiang X.;  Zhang Y.;  Shi Q.
收藏  |  浏览/下载:37/0  |  提交时间:2021/09/01
Human infertility  Meiotic arrest  Meiotic DSB formation failure  Oocyte maturation failure  Programmed meiotic DNA double-strand breaks  TOP6BLmutation  
Deterministic reversal of single magnetic vortex circulation by an electric field 期刊论文
Science Bulletin, 2020, 卷号: 65, 期号: 15
作者:  Zhang Y.;  Wang C.;  Huang H.;  Lu J.;  Liang R.;  Liu J.;  Peng R.;  Zhang Q.;  Zhang Q.;  Wang J.;  Gu L.;  Han X.-F.;  Chen L.-Q.;  Ramesh R.;  Nan C.-W.;  Zhang J.
收藏  |  浏览/下载:33/0  |  提交时间:2021/09/01
Deterministic reversal  Electric-field control  Multiferroic heterostructures  Single magnetic vortex  Space-varying strain