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Complete biosynthesis of the potential medicine icaritin by engineered Saccharomyces cerevisiae and Escherichia coli 期刊论文
Science Bulletin, 2021
作者:  Wang P.;  Li C.;  Li X.;  Huang W.;  Wang Y.;  Wang J.;  Zhang Y.;  Yang X.;  Yan X.;  Wang Y.;  Zhou Z.
收藏  |  浏览/下载:25/0  |  提交时间:2021/09/01
Efficacy and safety of chiglitazar, a novel peroxisome proliferator-activated receptor pan-agonist, in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled, phase 3 trial (CMAP) 期刊论文
Science Bulletin, 2021, 卷号: 66, 期号: 15
作者:  Ji L.;  Song W.;  Fang H.;  Li W.;  Geng J.;  Wang Y.;  Guo L.;  Cai H.;  Yang T.;  Li H.;  Yang G.;  Li Q.;  Liu K.;  Li S.;  Liu Y.;  Shi F.;  Li X.;  Gao X.;  Tian H.;  Ji Q.;  Su Q.;  Zhou Z.;  Wang W.;  Zhou Z.;  Li X.;  Xu Y.;  Ning Z.;  Cao H.;  Pan D.;  Yao H.;  Lu X.;  Jia W.
收藏  |  浏览/下载:39/0  |  提交时间:2021/09/01
Carfloglitazar  Chiglitazar  Glycemic control  Insulin resistance  PPAR pan-agonist  Type 2 diabetes  
Acidic pH transiently prevents the silencing of self-renewal and dampens microRNA function in embryonic stem cells 期刊论文
Science Bulletin, 2021, 卷号: 66, 期号: 13
作者:  Guo W.;  Wang S.;  Zhang X.;  Shi M.;  Duan F.;  Hao J.;  Gu K.;  Quan L.;  Wu Y.;  Liang Z.;  Wang Y.
收藏  |  浏览/下载:30/0  |  提交时间:2021/09/01
Acidic pH  Embryonic stem cells  Glycolysis  Lactate  Pluripotency  
Optimizing antithymocyte globulin dosing in haploidentical hematopoietic cell transplantation: long-term follow-up of a multicenter, randomized controlled trial 期刊论文
Science Bulletin, 2021
作者:  Wang Y.;  Liu Q.-F.;  Lin R.;  Yang T.;  Xu Y.-J.;  Mo X.-D.;  Huang X.-J.
收藏  |  浏览/下载:24/0  |  提交时间:2021/09/01
Antithymocyte globulin  Chronic graft-versus-host disease  GVHD-free/relapse-free survival  Haematopoietic cell transplantation  Haploidentical  Late effects  
Early role for a Na+,K+-ATPase (ATP1A3) in brain development 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 25
作者:  Smith R.S.;  Florio M.;  Akula S.K.;  Neil J.E.;  Wang Y.;  Sean Hill R.;  Goldman M.;  Mullally C.D.;  Reed N.;  Bello-Espinosa L.;  Flores-Sarnat L.;  Monteiro F.P.;  Erasmo C.B.;  Vairo F.P.E.;  Morava E.;  James Barkovich A.;  Gonzalez-Heydrich J.;  Brownstein C.A.;  McCarroll S.A.;  Walsh C.A.
收藏  |  浏览/下载:24/0  |  提交时间:2022/02/22
Toll9 from Bombyx mori functions as a pattern recognition receptor that shares features with Toll-like receptor 4 from mammals 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 19
作者:  Zhang R.;  Li X.;  Zhang J.;  Li Y.;  Wang Y.;  Song Y.;  Ren F.;  Yi H.;  Deng X.;  Zhong Y.;  Cao Y.;  Strand M.R.;  Yu X.-Q.;  Yang W.
收藏  |  浏览/下载:120/0  |  提交时间:2022/02/22
EIN3 and RSL4 interfere with an MYB–bHLH–WD40 complex to mediate ethylene-induced ectopic root hair formation in Arabidopsis 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 51
作者:  Qiu Y.;  Tao R.;  Feng Y.;  Xiao Z.;  Zhang D.;  Peng Y.;  Wen X.;  Wang Y.;  Guo H.
收藏  |  浏览/下载:30/0  |  提交时间:2022/02/22
Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells 期刊论文
, 2020, 卷号: 368, 期号: 6494
作者:  Zhou Z.;  He H.;  Wang K.;  Shi X.;  Wang Y.;  Su Y.;  Wang Y.;  Li D.;  Liu W.;  Zhang Y.;  Shen L.;  Han W.;  Shen L.;  Ding J.;  Shao F.
收藏  |  浏览/下载:26/0  |  提交时间:2020/07/28
cell  cell component  cytology  enzyme  enzyme activity  gene expression  immunity  tumor  Mus  gamma interferon  granzyme  GSDMB protein, human  GZMA protein, human  pore forming cytotoxic protein  tumor protein  animal  Bagg albino mouse  chemistry  cytotoxic T lymphocyte  enzymology  genetics  HEK293 cell line  human  immunology  metabolism  mouse  natural killer cell  neoplasm  pathology  protein degradation  protein domain  pyroptosis  transgenic mouse  Animals  Granzymes  HEK293 Cells  Humans  Interferon-gamma  Killer Cells, Natural  Mice  Mice, Inbred BALB C  Mice, Transgenic  Neoplasm Proteins  Neoplasms  Pore Forming Cytotoxic Proteins  Protein Domains  Proteolysis  Pyroptosis  T-Lymphocytes, Cytotoxic