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Comprehensive Analyses and Prioritization of Tox21 10K Chemicals Affecting Mitochondrial Function by in-Depth Mechanistic Studies 期刊论文
ENVIRONMENTAL HEALTH PERSPECTIVES, 2018, 卷号: 126, 期号: 7
作者:  Xia, Menghang;  Huang, Ruili;  Shi, Qiang;  Boyd, Windy A.;  Zhao, Jinghua;  Sun, Nuo;  Rice, Julie R.;  Dunlap, Paul E.;  Hackstadt, Amber J.;  Bridge, Matt F.;  Smith, Marjolein V.;  Dai, Sheng;  Zheng, Wei;  Chu, Pei-Hsuan;  Gerhold, David;  Witt, Kristine L.;  DeVito, Michael;  Freedman, Jonathan H.;  Austin, Christopher P.;  Houck, Keith A.;  Thomas, Russell S.;  Paules, Richard S.;  Tice, Raymond R.;  Simeonov, Anton
收藏  |  浏览/下载：54/0  |  提交时间：2019/05/04
Identifying environmental chemicals as agonists of the androgen receptor by using a quantitative high-throughput screening platform 期刊论文
TOXICOLOGY, 2017, 卷号: 385, 页码: 48-58
作者:  Lynch, Caitlin;  Sakamuru, Srilatha;  Huang, Ruili;  Stavreva, Diana A.;  Varticovski, Lyuba;  Hager, Gordon L.;  Judson, Richard S.;  Houck, Keith A.;  Kleinstreuer, Nicole C.;  Casey, Warren;  Paules, Richard S.;  Simeonov, Anton;  Xia, Menghang
收藏  |  浏览/下载：33/0  |  提交时间：2019/05/04
Development and Validation of a Computational Model for Androgen Receptor Activity 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2017, 卷号: 30, 期号: 4, 页码: 946-964
作者:  Kleinstreuer, Nicole C.;  Ceger, Patricia;  Watt, Eric D.;  Martin, Matthew;  Houck, Keith;  Browne, Patience;  Thomas, Russell S.;  Casey, Warren M.;  Dix, David J.;  Allen, David;  Sakamuru, Srilatha;  Xia, Menghang;  Huang, Ruili;  Judson, Richard
收藏  |  浏览/下载：33/0  |  提交时间：2019/05/04
Integrating Drug's Mode of Action into Quantitative Structure-Activity Relationships for Improved Prediction of Drug-Induced Liver Injury 期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2017, 卷号: 57, 期号: 4, 页码: 1000-1006
作者:  Wu, Leihong;  Liu, Zhichao;  Auerbach, Scott;  Huang, Ruili;  Chen, Minjun;  McEuen, Kristin;  Xu, Joshua;  Fang, Hong;  Tong, Weida
收藏  |  浏览/下载：32/0  |  提交时间：2019/05/04
Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space 期刊论文
TOXICOLOGICAL SCIENCES, 2016, 卷号: 152, 期号: 2, 页码: 323-339
作者:  Judson, Richard;  Houck, Keith;  Martin, Matt;  Richard, Ann M.;  Knudsen, Thomas B.;  Shah, Imran;  Little, Stephen;  Wambaugh, John;  Setzer, R. Woodrow;  Kothya, Parth;  Phuong, Jimmy;  Filer, Dayne;  Smith, Doris;  Reif, David;  Rotroff, Daniel;  Kleinstreuer, Nicole;  Sipes, Nisha;  Xia, Menghang;  Huang, Ruili;  Crofton, Kevin;  Thomas, Russell S.
收藏  |  浏览/下载：33/0  |  提交时间：2019/05/04
CERAPP: Collaborative Estrogen Receptor Activity Prediction Project 期刊论文
ENVIRONMENTAL HEALTH PERSPECTIVES, 2016, 卷号: 124, 期号: 7, 页码: 1023-1033
作者:  Mansouri, Kamel;  Abdelaziz, Ahmed;  Rybacka, Aleksandra;  Roncaglioni, Alessandra;  Tropsha, Alexander;  Varnek, Alexandre;  Zakharov, Alexey;  Worth, Andrew;  Richard, Ann M.;  Grulke, Christopher M.;  Trisciuzzi, Daniela;  Fourches, Denis;  Horvath, Dragos;  Benfenati, Emilio;  Muratov, Eugene;  Wedebye, Eva Bay;  Grisoni, Francesca;  Mangiatordi, Giuseppe F.;  Incisivo, Giuseppina M.;  Hong, Huixiao;  Ng, Hui W.;  Tetko, Igor V.;  Balabin, Ilya;  Kancherla, Jayaram;  Shen, Jie;  Burton, Julien;  Nicklaus, Marc;  Cassotti, Matteo;  Nikolov, Nikolai G.;  Nicolotti, Orazio;  Andersson, Patrik L.;  Zang, Qingda;  Politi, Regina;  Beger, Richard D.;  Todeschini, Roberto;  Huang, Ruili;  Farag, Sherif;  Rosenberg, Sine A.;  Slavov, Svetoslav;  Hu, Xin;  Judson, Richard S.
收藏  |  浏览/下载：30/0  |  提交时间：2019/05/04
Integrated Model of Chemical Perturbations of a Biological Pathway Using 18 In Vitro High-Throughput Screening Assays for the Estrogen Receptor 期刊论文
TOXICOLOGICAL SCIENCES, 2015, 卷号: 148, 期号: 1, 页码: 137-154
作者:  Judson, Richard S.;  Magpantay, Felicia Maria;  Chickarmane, Vijay;  Haskell, Cymra;  Tania, Nessy;  Taylor, Jean;  Xia, Menghang;  Huang, Ruili;  Rotroff, Daniel M.;  Filer, Dayne L.;  Houck, Keith A.;  Martin, Matthew T.;  Sipes, Nisha;  Richard, Ann M.;  Mansouri, Kamel;  Setzer, R. Woodrow;  Knudsen, Thomas B.;  Crofton, Kevin M.;  Thomas, Russell S.
收藏  |  浏览/下载：48/0  |  提交时间：2019/05/04
Population-Based in Vitro Hazard and Concentration-Response Assessment of Chemicals: The 1000 Genomes High-Throughput Screening Study 期刊论文
ENVIRONMENTAL HEALTH PERSPECTIVES, 2015, 卷号: 123, 期号: 5, 页码: 458-466
作者:  Abdo, Nour;  Xia, Menghang;  Brown, Chad C.;  Kosyk, Oksana;  Huang, Ruili;  Sakamuru, Srilatha;  Zhou, Yi-Hui;  Jack, John R.;  Gallins, Paul;  Xia, Kai;  Li, Yun;  Chiu, Weihsueh A.;  Motsinger-Reif, Alison A.;  Austin, Christopher P.;  Tice, Raymond R.;  Rusyn, Ivan;  Wright, Fred A.
收藏  |  浏览/下载：39/0  |  提交时间：2019/05/04
Profiling of the Tox21 Chemical Collection for Mitochondrial Function to Identify Compounds that Acutely Decrease Mitochondrial Membrane Potential 期刊论文
ENVIRONMENTAL HEALTH PERSPECTIVES, 2015, 卷号: 123, 期号: 1, 页码: 49-56
作者:  Attene-Ramos, Matias S.;  Huang, Ruili;  Michael, Sam;  Witt, Kristine L.;  Richard, Ann;  Tice, Raymond R.;  Simeonov, Anton;  Austin, Christopher P.;  Xia, Menghang
收藏  |  浏览/下载：31/0  |  提交时间：2019/05/04
Quantitative High-Throughput Profiling of Environmental Chemicals and Drugs that Modulate Farnesoid X Receptor 期刊论文
SCIENTIFIC REPORTS, 2014, 卷号: 4
作者:  Hsu, Chia-Wen;  Zhao, Jinghua;  Huang, Ruili;  Hsieh, Jui-Hua;  Hamm, Jon;  Chang, Xiaoqing;  Houck, Keith;  Xia, Menghang
收藏  |  浏览/下载：30/0  |  提交时间：2019/05/04