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Temperature sensitivity of Notch signaling underlies species-specific developmental plasticity and robustness in amniote brains 期刊论文
Nature Communications, 2022, 卷号: 13, 期号: 1
作者:  Nomura T.;  Nagao K.;  Shirai R.;  Gotoh H.;  Umeda M.;  Ono K.
收藏  |  浏览/下载:26/0  |  提交时间:2022/02/22
Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 10
作者:  Tsai P.-Y.;  Lee M.-S.;  Jadhav U.;  Naqvi I.;  Madha S.;  Adler A.;  Mistry M.;  Naumenko S.;  Lewis C.A.;  Hitchcock D.S.;  Roberts F.R.;  DelNero P.;  Hank T.;  Honselmann K.C.;  Oyarvide V.M.;  Mino-Kenudson M.;  Clish C.B.;  Shivdasani R.A.;  Kalaany N.Y.
收藏  |  浏览/下载:34/0  |  提交时间:2021/05/24
Metabolic supervision by PPIP5K, an inositol pyrophosphate kinase/phosphatase, controls proliferation of the HCT116 tumor cell line 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 10
作者:  Gu C.;  Liu J.;  Liu X.;  Zhang H.;  Luo J.;  Wang H.;  Locasale J.W.;  Shears S.B.
收藏  |  浏览/下载:25/0  |  提交时间:2021/05/24
Monocarboxylate transporter antagonism reveals metabolic vulnerabilities of viral-driven lymphomas 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 25
作者:  Bonglack E.N.;  Messinger J.E.;  Cable J.M.;  Chng J.;  Mark Parnell K.;  Reinoso-Vizcaíno N.M.;  Barry A.P.;  Russell V.S.;  Dave S.S.;  Christofk H.R.;  Luftig M.A.
收藏  |  浏览/下载:34/0  |  提交时间:2021/11/25
Critical role of the CD44lowCD62Llow CD8+ T cell subset in restoring antitumor immunity in aged mice 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 23
作者:  Nakajima Y.;  Chamoto K.;  Oura T.;  Honjo T.
收藏  |  浏览/下载:22/0  |  提交时间:2021/11/25
Systems level profiling of chemotherapy-induced stress resolution in cancer cells reveals druggable trade-offs 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 17
作者:  Saavedra-García P.;  Roman-Trufero M.;  Al-Sadah H.A.;  Blighe K.;  López-Jiménez E.;  Christoforou M.;  Penfold L.;  Capece D.;  Xiong X.;  Miao Y.;  Parzych K.;  Caputo V.S.;  Siskos A.P.;  Encheva V.;  Liu Z.;  Thiel D.;  Kaiser M.F.;  Piazza P.;  Chaidos A.;  Karadimitris A.;  Franzoso G.;  Snijders A.P.;  Keun H.C.;  Oyarzún D.A.;  Barahona M.;  Auner H.W.
收藏  |  浏览/下载:30/0  |  提交时间:2021/05/24
Oncogenic lncRNA LINC00973 promotes warburg effect by enhancing LDHA enzyme activity 期刊论文
Science Bulletin, 2021
作者:  Wang H.;  Lin K.;  Zhu L.;  Zhang S.;  Li L.;  Liao Y.;  Zhang B.;  Yang M.;  Liu X.;  Li L.;  Li S.;  Yang L.;  Wang H.;  Wang Q.;  Li H.;  Fu S.;  Zhang X.;  Jiang P.;  Zhang Q.C.;  Cheng J.;  Wang D.
收藏  |  浏览/下载:39/0  |  提交时间:2021/09/01
Biomarker  Cancer metabolism  LDHA  LINC00973  Warburg effect  
Acidic pH transiently prevents the silencing of self-renewal and dampens microRNA function in embryonic stem cells 期刊论文
Science Bulletin, 2021, 卷号: 66, 期号: 13
作者:  Guo W.;  Wang S.;  Zhang X.;  Shi M.;  Duan F.;  Hao J.;  Gu K.;  Quan L.;  Wu Y.;  Liang Z.;  Wang Y.
收藏  |  浏览/下载:30/0  |  提交时间:2021/09/01
Acidic pH  Embryonic stem cells  Glycolysis  Lactate  Pluripotency  
A glutaminase isoform switch drives therapeutic resistance and disease progression of prostate cancer 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 13
作者:  Xu L.;  Yin Y.;  Li Y.;  Chen X.;  Chang Y.;  Zhang H.;  Liu J.;  Beasley J.;  McCaw P.;  Zhang H.;  Young S.;  Groth J.;  Wang Q.;  Locasale J.W.;  Gao X.;  Tang D.G.;  Dong X.;  He Y.;  George D.;  Hu H.;  Huang J.
收藏  |  浏览/下载:32/0  |  提交时间:2021/05/24
p53 deficiency induces MTHFD2 transcription to promote cell proliferation and restrain DNA damage 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 28
作者:  Li G.;  Wu J.;  Li L.;  Jiang P.
收藏  |  浏览/下载:1/0  |  提交时间:2021/11/25