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The genetic architecture of the human cerebral cortex 期刊论文
, 2020, 卷号: 367, 期号: 6484
作者:  Grasby K.L.;  Jahanshad N.;  Painter J.N.;  Colodro-Conde L.;  Bralten J.;  Hibar D.P.;  Lind P.A.;  Pizzagalli F.;  Ching C.R.K.;  McMahon M.A.B.;  Shatokhina N.;  Zsembik L.C.P.;  Thomopoulos S.I.;  Zhu A.H.;  Strike L.T.;  Agartz I.;  Alhusaini S.;  Almeida M.A.A.;  Alnæs D.;  Amlien I.K.;  Andersson M.;  Ard T.;  Armstrong N.J.;  Ashley-Koch A.;  Atkins J.R.;  Bernard M.;  Brouwer R.M.;  Buimer E.E.L.;  Bülow R.;  Bürger C.;  Cannon D.M.;  Chakravarty M.;  Chen Q.;  Cheung J.W.;  Couvy-Duchesne B.;  Dale A.M.;  Dalvie S.;  de Araujo T.K.;  de Zubicaray G.I.;  de Zwarte S.M.C.;  den Braber A.;  Doan N.T.;  Dohm K.;  Ehrlich S.;  Engelbrecht H.-R.;  Erk S.;  Fan C.C.;  Fedko I.O.;  Foley S.F.;  Ford J.M.;  Fukunaga M.;  Garrett M.E.;  Ge T.;  Giddaluru S.;  Goldman A.L.;  Green M.J.;  Groenewold N.A.;  Grotegerd D.;  Gurholt T.P.;  Gutman B.A.;  Hansell N.K.;  Harris M.A.;  Harrison M.B.;  Haswell C.C.;  Hauser M.;  Herms S.;  Heslenfeld D.J.;  Ho N.F.;  Hoehn D.;  Hoffmann P.;  Holleran L.;  Hoogman M.;  Hottenga J.-J.;  Ikeda M.;  Janowitz D.;  Jansen I.E.;  Jia T.;  Jockwitz C.;  Kanai R.;  Karama S.;  Kasperaviciute D.;  Kaufmann T.;  Kelly S.;  Kikuchi M.;  Klein M.;  Knapp M.;  Knodt A.R.;  Krämer B.;  Lam M.;  Lancaster T.M.;  Lee P.H.;  Lett T.A.;  Lewis L.B.;  Lopes-Cendes I.;  Luciano M.;  Macciardi F.;  Marquand A.F.;  Mathias S.R.;  Melzer T.R.;  Milaneschi Y.;  Mirza-Schreiber N.;  Moreira J.C.V.;  Mühleisen T.W.;  Müller-Myhsok B.;  Najt P.;  Nakahara S.;  Nho K.;  Olde Loohuis L.M.;  Orfanos D.P.;  Pearson J.F.;  Pitcher T.L.;  Pütz B.;  Quidé Y.;  Ragothaman A.;  Rashid F.M.;  Reay W.R.;  Redlich R.;  Reinbold C.S.;  Repple J.;  Richard G.;  Riedel B.C.;  Risacher S.L.;  Rocha C.S.;  Mota N.R.;  Salminen L.;  Saremi A.;  Saykin A.J.;  Schlag F.;  Schmaal L.;  Schofield P.R.;  Secolin R.;  Shapland C.Y.;  Shen L.;  Shin J.;  Shumskaya E.;  Sønderby I.E.;  Sprooten E.;  Tansey K.E.;  Teumer A.;  Thalamuthu A.;  Tordesillas-Gutiérrez D.;  Turner J.A.;  Uhlmann A.;  Vallerga C.L.;  van der Meer D.;  van Donkelaar M.M.J.;  van Eijk L.;  van Erp T.G.M.;  van Haren N.E.M.;  van Rooij D.;  van Tol M.-J.;  Veldink J.H.;  Verhoef E.;  Walton E.;  Wang M.;  Wang Y.;  Wardlaw J.M.;  Wen W.;  Westlye L.T.;  Whelan C.D.;  Witt S.H.;  Wittfeld K.;  Wolf C.;  Wolfers T.;  Wu J.Q.;  Yasuda C.L.;  Zaremba D.;  Zhang Z.;  Zwiers M.P.;  Artiges E.;  Assareh A.A.;  Ayesa-Arriola R.;  Belger A.;  Brandt C.L.;  Brown G.G.;  Cichon S.;  Curran J.E.;  Davies G.E.;  Degenhardt F.;  Dennis M.F.;  Dietsche B.;  Djurovic S.;  Doherty C.P.;  Espiritu R.;  Garijo D.;  Gil Y.;  Gowland P.A.;  Green R.C.;  Häusler A.N.;  Heindel W.;  Ho B.-C.;  Hoffmann W.U.;  Holsboer F.;  Homuth G.;  Hosten N.;  Jack C.R.;  Jang M.;  Jansen A.;  Kimbrel N.A.;  Kolskår K.;  Koops S.;  Krug A.;  Lim K.O.;  Luykx J.J.;  Mathalon D.H.;  Mather K.A.;  Mattay V.S.;  Matthews S.;  van Son J.M.;  McEwen S.C.;  Melle I.;  Morris D.W.;  Mueller B.A.;  Nauck M.;  Nordvik J.E.;  Nöthen M.M.;  O'Leary D.S.;  Opel N.;  Martinot M.-L.P.;  Bruce Pike G.;  Preda A.;  Quinlan E.B.;  Rasser P.E.;  Ratnakar V.;  Reppermund S.;  Steen V.M.;  Tooney P.A.;  Torres F.R.;  Veltman D.J.;  Voyvodic J.T.;  Whelan R.;  White T.;  Yamamori H.;  Adams H.H.H.;  Bis J.C.;  Debette S.;  Decarli C.;  Fornage M.;  Gudnason V.;  Hofer E.;  Arfan Ikram M.;  Launer L.;  Longstreth W.T.;  Lopez O.L.;  Mazoyer B.;  Mosley T.H.;  Roshchupkin G.V.;  Satizabal C.L.;  Schmidt R.;  Seshadri S.;  Yang Q.;  Alvim M.K.M.;  Ames D.;  Anderson T.J.;  Andreassen O.A.;  Arias-Vasquez A.;  Bastin M.E.;  Baune B.T.;  Beckham J.C.;  Blangero J.;  Boomsma D.I.;  Brodaty H.;  Brunner H.G.;  Buckner R.L.;  Buitelaar J.K.;  Bustillo J.R.;  Cahn W.;  Cairns M.J.;  Calhoun V.;  Carr V.J.;  Caseras X.;  Caspers S.;  Cavalleri G.L.;  Cendes F.;  Corvin A.;  Crespo-Facorro B.;  Dalrymple-Alford J.C.;  Dannlowski U.;  de Geus E.J.C.;  Deary I.J.;  Delanty N.;  Depondt C.;  Desrivières S.;  Donohoe G.;  Espeseth T.;  Fernández G.;  Fisher S.E.;  Flor H.;  Forstner A.J.;  Francks C.;  Franke B.;  Glahn D.C.;  Gollub R.L.;  Grabe H.J.;  Gruber O.;  Håberg A.K.;  Hariri A.R.;  Hartman C.A.;  Hashimoto R.;  Heinz A.;  Henskens F.A.;  Hillegers M.H.J.;  Hoekstra P.J.;  Holmes A.J.;  Elliot Hong L.;  Hopkins W.D.;  Hulshoff Pol H.E.;  Jernigan T.L.;  Jönsson E.G.;  Kahn R.S.;  Kennedy M.A.;  Kircher T.T.J.;  Kochunov P.;  Kwok J.B.J.;  Le Hellard S.;  Loughland C.M.;  Martin N.G.;  Martinot J.-L.;  McDonald C.;  McMahon K.L.;  Meyer-Lindenberg A.;  Michie P.T.;  Morey R.A.;  Mowry B.;  Nyberg L.;  Oosterlaan J.;  Ophoff R.A.;  Pantelis C.;  Paus T.;  Pausova Z.;  Penninx B.W.J.H.;  Polderman T.J.C.;  Posthuma D.;  Rietschel M.;  Roffman J.L.;  Rowland L.M.;  Sachdev P.S.;  Sämann P.G.;  Schall U.;  Schumann G.;  Scott R.J.;  Sim K.;  Sisodiya S.M.;  Smoller J.W.;  Sommer I.E.;  Pourcain B.S.;  Stein D.J.;  Toga A.W.;  Trollor J.N.;  van der Wee N.J.A.;  van't Ent D.;  Völzke H.;  Walter H.;  Weber B.;  Weinberger D.R.;  Wright M.J.;  Zhou J.;  Stein J.L.;  Thompson P.M.;  Medland S.E.;  Enhancing NeuroImaging Genetics through Meta-Analysis Consortium (ENIGMA)-Genetics working group
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brain  genetic analysis  meta-analysis  resonance  signaling  surface area  Article  bioinformatics  brain cortex  brain function  brain region  brain tissue  cortical thickness (brain)  educational status  evidence based medicine  gene control  gene locus  genetic association  genetic correlation  genetic variability  genome-wide association study  human  human genetics  priority journal  surface area  tissue structure  Wnt signaling  anatomy and histology  attention deficit disorder  brain cortex  brain mapping  cognition  genetic variation  genetics  meta analysis  nuclear magnetic resonance imaging  organ size  Parkinson disease  Attention Deficit Disorder with Hyperactivity  Brain Mapping  Cerebral Cortex  Cognition  Genetic Loci  Genetic Variation  Genome-Wide Association Study  Humans  Magnetic Resonance Imaging  Organ Size  Parkinson Disease  
Different genetic barriers for resistance to HA stem antibodies in influenza H3 and H1 viruses 期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:  Wu N.C.;  Thompson A.J.;  Lee J.M.;  Su W.;  Arlian B.M.;  Xie J.;  Lerner R.A.;  Yen H.-L.;  Bloom J.D.;  Wilson I.A.
收藏  |  浏览/下载:21/0  |  提交时间:2020/07/28
genetic analysis  hematology  influenza  mutation  pathogenicity  vaccine  virus  epitope  influenza vaccine  Influenza virus hemagglutinin  neutralizing antibody  virus antibody  chemistry  genetics  human  immunological tolerance  immunology  Influenza A virus (H1N1)  Influenza A virus (H3N2)  mutation  Antibodies, Neutralizing  Antibodies, Viral  Hemagglutinin Glycoproteins, Influenza Virus  Humans  Immune Tolerance  Immunodominant Epitopes  Influenza A Virus, H1N1 Subtype  Influenza A Virus, H3N2 Subtype  Influenza Vaccines  Mutation  
Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis 期刊论文
, 2020, 卷号: 367, 期号: 6485
作者:  Ebright R.Y.;  Lee S.;  Wittner B.S.;  Niederhoffer K.L.;  Nicholson B.T.;  Bardia A.;  Truesdell S.;  Wiley D.F.;  Wesley B.;  Li S.;  Mai A.;  Aceto N.;  Vincent-Jordan N.;  Szabolcs A.;  Chirn B.;  Kreuzer J.;  Comaills V.;  Kalinich M.;  Haas W.;  Ting D.T.;  Toner M.;  Vasudevan S.;  Haber D.A.;  Maheswaran S.;  Micalizzi D.S.
收藏  |  浏览/下载:45/0  |  提交时间:2020/07/28
CRISPR associated protein  epidermal growth factor receptor 2  Ki 67 antigen  ribosome protein  ribosome RNA  transcription factor E2F  ribosome protein  cancer  cell  gene expression  genetic engineering  protein  RNA  tumor  animal experiment  animal model  animal tissue  Article  biogenesis  bioluminescence  breast cancer  cell cycle progression  cell cycle regulation  cell proliferation  circulating tumor cell  controlled study  enzyme activation  epithelial mesenchymal transition  gene expression profiling  genetic transcription  human  human cell  lung metastasis  metastasis  microfluidics  mouse  nonhuman  overall survival  phenotype  priority journal  progression free survival  promoter region  protein expression  protein processing  protein synthesis  proteomics  RNA sequence  transcription regulation  animal  breast tumor  cancer transplantation  CRISPR Cas system  female  gene expression regulation  genetics  pathology  sequence analysis  tumor cell line  tumor embolism  Mus  Animals  Breast Neoplasms  Cell Line, Tumor  CRISPR-Cas Systems  Female  Gene Expression Regulation, Neoplastic  Humans  Mice  Neoplasm Metastasis  Neoplasm Transplantation  Neoplastic Cells, Circulating  Ribosomal Proteins  Sequence Analysis, RNA  
Cysteine depletion induces pancreatic tumor ferroptosis in mice 期刊论文
, 2020, 卷号: 368, 期号: 6486
作者:  Badgley M.A.;  Kremer D.M.;  Carlo Maurer H.;  DelGiorno K.E.;  Lee H.-J.;  Purohit V.;  Sagalovskiy I.R.;  Ma A.;  Kapilian J.;  Firl C.E.M.;  Decker A.R.;  Sastra S.A.;  Palermo C.F.;  Andrade L.R.;  Sajjakulnukit P.;  Zhang L.;  Tolstyka Z.P.;  Hirschhorn T.;  Lamb C.;  Liu T.;  Gu W.;  Scott Seeley E.;  Stone E.;  Georgiou G.;  Manor U.;  Iuga A.;  Wahl G.M.;  Stockwell B.R.;  Lyssiotis C.A.;  Olive K.P.
收藏  |  浏览/下载:31/0  |  提交时间:2020/07/28
coenzyme A  cysteine  glutathione  amino acid  induced response  rodent  tumor  animal experiment  animal model  animal tissue  Article  cell death  cell survival  cell viability  controlled study  down regulation  ferroptosis  fragmentation reaction  human  human cell  lipid oxidation  lipophilicity  mouse  necroptosis  nonhuman  pancreas tumor  pancreatic ductal carcinoma cell line  priority journal  protein cleavage  protein expression  tumor growth  tumor microenvironment  tumor xenograft  Mus  
Structural evidence for a dynamic metallocofactor during N2 reduction by Mo-nitrogenase 期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:  Kang W.;  Lee C.C.;  Jasniewski A.J.;  Ribbe M.W.;  Hu Y.
收藏  |  浏览/下载:41/0  |  提交时间:2020/07/28
ammonia  catalysis  crystal structure  enzyme activity  ligand  physiological response  sulfur  ligand  molybdenum iron protein  nitrogen  sulfur  Azotobacter vinelandii  biocatalysis  chemistry  enzymology  oxidation reduction reaction  protein multimerization  X ray crystallography  Azotobacter vinelandii  Biocatalysis  Crystallography, X-Ray  Ligands  Molybdoferredoxin  Nitrogen  Oxidation-Reduction  Protein Multimerization  Sulfur