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A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV
期刊论文
, 2020, 卷号: 368, 期号: 6491
作者:
Yuan M.
;
Wu N.C.
;
Zhu X.
;
Lee C.-C.D.
;
So R.T.Y.
;
Lv H.
;
Mok C.K.P.
;
Wilson I.A.
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/28
angiotensin converting enzyme 2
epitope
neutralizing antibody
virus hemagglutinin
virus spike protein
angiotensin converting enzyme 2
coronavirus receptors
coronavirus spike glycoprotein
dipeptidyl carboxypeptidase
epitope
neutralizing antibody
spike glycoprotein, SARS-CoV
spike protein, SARS-CoV-2
virus antibody
virus antigen
virus receptor
antibody
antigen
chemical binding
crystal structure
protein
respiratory disease
viral disease
virus
amino terminal sequence
antibody isolation
antigen binding
antigenicity
Article
binding affinity
binding site
conservation biology
controlled study
coronavirus disease 2019
cross reaction
cryoelectron microscopy
crystal structure
enzyme linked immunosorbent assay
epidemic
glycosylation
human
hydrophobicity
immune response
in vitro study
in vivo study
light chain
nonhuman
priority journal
protein conformation
protein domain
protein interaction
protein localization
protein structure
protein targeting
receptor binding
SARS coronavirus
Severe acute respiratory syndrome coronavirus 2
amino acid sequence
antibody affinity
Betacoronavirus
binding site
chemistry
immunology
metabolism
molecular model
SARS coronavirus
X ray crystallography
Coronavirus
SARS coronavirus
Amino Acid Sequence
Antibodies, Neutralizing
Antibodies, Viral
Antibody Affinity
Antigens, Viral
Betacoronavirus
Binding Sites
Cross Reactions
Crystallography, X-Ray
Epitopes
Models, Molecular
Peptidyl-Dipeptidase A
Protein Conformation
Protein Domains
Protein Interaction Domains and Motifs
Receptors, Virus
SARS Virus
Spike Glycoprotein, Coronavirus
Quantifying SARS-CoV-2 transmission suggests epidemic control with digital contact tracing
期刊论文
, 2020, 卷号: 368, 期号: 6491
作者:
Ferretti L.
;
Wymant C.
;
Kendall M.
;
Zhao L.
;
Nurtay A.
;
Abeler-Dörner L.
;
Parker M.
;
Bonsall D.
;
Fraser C.
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/28
disease control
epidemic
memory
parasite transmission
viral disease
Article
asymptomatic disease
China
contact examination
coronavirus disease 2019
disease control
disease transmission
health care system
human
incubation time
mathematical model
mobile application
mortality rate
priority journal
quarantine
rating scale
Severe acute respiratory syndrome coronavirus 2
virus transmission
algorithm
basic reproduction number
Betacoronavirus
contact examination
Coronavirus infection
epidemic
ethics
infection control
mobile application
mobile phone
pandemic
probability
procedures
theoretical model
time factor
virus pneumonia
Coronavirus
SARS coronavirus
Algorithms
Asymptomatic Diseases
Basic Reproduction Number
Betacoronavirus
Cell Phone
China
Contact Tracing
Coronavirus Infections
Epidemics
Humans
Infection Control
Mobile Applications
Models, Theoretical
Pandemics
Pneumonia, Viral
Probability
Quarantine
Time Factors
The effect of human mobility and control measures on the COVID-19 epidemic in China
期刊论文
, 2020, 卷号: 368, 期号: 6490
作者:
Kraemer M.U.G.
;
Yang C.-H.
;
Gutierrez B.
;
Wu C.-H.
;
Klein B.
;
Pigott D.M.
;
du Plessis L.
;
Faria N.R.
;
Li R.
;
Hanage W.P.
;
Brownstein J.S.
;
Layan M.
;
Vespignani A.
;
Tian H.
;
Dye C.
;
Pybus O.G.
;
Scarpino S.V.
;
Open COVID-19 Data Working Group
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2020/07/28
aging
Article
China
coronavirus disease 2019
crowdsourcing
disease transmission
epidemic
geographic distribution
growth rate
human
import disease
incidence
infection control
infection risk
population dynamics
priority journal
risk factor
Severe acute respiratory syndrome coronavirus 2
sex ratio
travel
Coronavirus
Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV-2)
期刊论文
, 2020, 卷号: 368, 期号: 6490
作者:
Li R.
;
Pei S.
;
Chen B.
;
Song Y.
;
Zhang T.
;
Yang W.
;
Shaman J.
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/07/28
disease prevalence
disease spread
disease transmission
infectious disease
metapopulation
population modeling
viral disease
virus
Article
Bayes theorem
China
conceptual framework
coronavirus disease 2019
data analysis
disease severity
disease transmission
documentation
human
mathematical model
metapopulation
nonhuman
priority journal
Severe acute respiratory syndrome coronavirus 2
travel
validation process
China
Coronavirus
SARS coronavirus
The coronavirus czar
期刊论文
, 2020, 卷号: 368, 期号: 6490
作者:
Kupferschmidt K.
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/28
epidemic
research work
symptom
vaccine
viral disease
virus
Article
coronavirus disease 2019
Germany
human
infection control
information dissemination
medical expert
medical research
pandemic
priority journal
sequence analysis
Severe acute respiratory syndrome coronavirus 2
social distance
virus identification
Betacoronavirus
Coronavirus infection
history
virology
virus pneumonia
Germany
Coronavirus
Betacoronavirus
Coronavirus Infections
Germany
History, 20th Century
History, 21st Century
Humans
Pandemics
Pneumonia, Viral
Virology
Promoting biosecurity by professionalizing biosecurity A credential system could improve policy and practice
期刊论文
, 2020, 卷号: 367, 期号: 6480
作者:
Moritz R.L.
;
Berger K.M.
;
Owen B.R.
;
Gillum D.R.
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/28
toxin
biosafety
credit provision
economic analysis
policy implementation
policy making
2019 novel coronavirus
accreditation
Article
biomedicine
biosafety
biotechnology
computer security
Coronavirinae
cyberattack
documentation
Ebolavirus
health hazard
human
infectious agent
information security
information system
interdisciplinary research
knowledge
material control and accountability
medical practice
microorganism
personal security
personnel suitability
physical security
policy
priority journal
professional competence
professional practice
professional standard
program management
protocol compliance
public health
risk management
Severe acute respiratory syndrome coronavirus 2
skill
stakeholder engagement
synthetic biology
threat
transport security
Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved a-ketoamide inhibitors
期刊论文
, 2020, 卷号: 368, 期号: 6489
作者:
Zhang L.
;
Lin D.
;
Sun X.
;
Curth U.
;
Drosten C.
;
Sauerhering L.
;
Becker S.
;
Rox K.
;
Hilgenfeld R.
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/07/28
alanine
alpha ketoamide inhibitor
antivirus agent
isoleucine
leucine
proteinase
Severe acute respiratory syndrome coronavirus 2 main protease
threonine
unclassified drug
crystal structure
drug
enzyme
enzyme activity
inhibitor
reaction kinetics
amino acid sequence
animal cell
animal experiment
animal tissue
antiviral activity
Article
catalysis
catalytic efficiency
controlled study
crystal structure
dimerization
dissociation constant
drug clearance
drug design
drug distribution
drug half life
drug potency
drug protein binding
drug solubility
drug structure
EC50
enzyme inhibition
human
human cell
hydrogen bond
hydrophobicity
IC50
maximum concentration
mean residence time
metabolic stability
mouse
nonhuman
priority journal
protein structure
RNA replication
SARS coronavirus
Severe acute respiratory syndrome coronavirus 2
viral tropism
virus inhibition
Coronavirus
SARS coronavirus
Airport screening is largely futile, research shows
期刊论文
, 2020, 卷号: 367, 期号: 6483
作者:
Normile D.
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/28
antipyretic agent
airport
airport
Article
body temperature measurement
China
contact examination
Coronavirinae
coronavirus disease 2019
Coronavirus infection
epidemic
false negative result
false positive result
fever
human
infection prevention
interview
Italy
medical examination
missed diagnosis
patient attitude
practice guideline
priority journal
questionnaire
screening test
severe acute respiratory syndrome coronavirus 2
skin temperature
South Korea
symptom
travel
United States
virus transmission
World Health Organization
Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2
期刊论文
, 2020, 卷号: 367, 期号: 6485
作者:
Yan R.
;
Zhang Y.
;
Li Y.
;
Xia L.
;
Guo Y.
;
Zhou Q.
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/28
angiotensin converting enzyme 2
coronavirus spike glycoprotein
heterodimer
homodimer
amino acid transporter
angiotensin converting enzyme 2
dipeptidyl carboxypeptidase
protein binding
SLC6A19 protein, human
spike protein, SARS-CoV-2
virus receptor
enzyme
gene
gene expression
protein
ultrastructure
virus
Article
binding site
complex formation
controlled study
coronavirus disease 2019
cryoelectron microscopy
dimerization
embryo
enzyme structure
human
human cell
nonhuman
priority journal
protein domain
SARS-related coronavirus
Severe acute respiratory syndrome coronavirus 2
amino acid sequence
Betacoronavirus
Coronavirus infection
molecular model
pandemic
protein multimerization
SARS coronavirus
sequence alignment
ultrastructure
virus pneumonia
Coronavirus
SARS coronavirus
Amino Acid Sequence
Amino Acid Transport Systems, Neutral
Betacoronavirus
Coronavirus Infections
Cryoelectron Microscopy
Humans
Models, Molecular
Pandemics
Peptidyl-Dipeptidase A
Pneumonia, Viral
Protein Binding
Protein Domains
Protein Multimerization
Receptors, Virus
SARS Virus
Sequence Alignment
Spike Glycoprotein, Coronavirus
Sick time
期刊论文
, 2020, 卷号: 367, 期号: 6484
作者:
Cohen J.
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/28
disease
public health
temporal analysis
Article
coronavirus disease 2019
Coronavirus infection
disease surveillance
disease transmission
help seeking behavior
human
humidity
immune system
incidence
infection sensitivity
Influenza virus
nonhuman
nose smear
pandemic
priority journal
SARS coronavirus
seasonal variation
Severe acute respiratory syndrome coronavirus 2
United Kingdom
virus viability
winter
Betacoronavirus
Coronavirus infection
female
male
microbial viability
physiology
season
viral phenomena and functions
virology
virus infection
virus pneumonia
weather
COVID-19
severe acute respiratory syndrome coronavirus 2
Betacoronavirus
Coronavirus Infections
Female
Humans
Male
Microbial Viability
Pneumonia, Viral
Seasons
Virus Diseases
Virus Physiological Phenomena
Weather