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Comparative pathogenesis of COVID-19, MERS, and SARS in a nonhuman primate model 期刊论文
, 2020, 卷号: 368, 期号: 6494
作者:  Rockx B.;  Kuiken T.;  Herfst S.;  Bestebroer T.;  Lamers M.M.;  Munnink B.B.O.;  De Meulder D.;  Van Amerongen G.;  Van Den Brand J.;  Okba N.M.A.;  Schipper D.;  Van Run P.;  Leijten L.;  Sikkema R.;  Verschoor E.;  Verstrepen B.;  Bogers W.;  Langermans J.;  Langermans J.;  Drosten C.;  Van Vlissingen M.F.;  Fouchier R.;  De Swart R.;  Koopmans M.;  Haagmans B.L.
收藏  |  浏览/下载：28/0  |  提交时间：2020/07/28
pathogenicity  pathology  primate  severe acute respiratory syndrome  viral disease  virus  Middle East  Coronavirus  Macaca  Primates  SARS coronavirus  aging  animal  Betacoronavirus  comparative study  Coronavirus infection  disease model  female  isolation and purification  lung  lung alveolus  Macaca fascicularis  Middle East respiratory syndrome coronavirus  pandemic  pathogenicity  pathology  physiology  respiratory system  SARS coronavirus  severe acute respiratory syndrome  virology  virus pneumonia  virus replication  virus shedding  Aging  Animals  Betacoronavirus  Coronavirus Infections  Disease Models, Animal  Female  Lung  Macaca fascicularis  Middle East Respiratory Syndrome Coronavirus  Pandemics  Pneumonia, Viral  Pulmonary Alveoli  Respiratory System  SARS Virus  Severe Acute Respiratory Syndrome  Virus Replication  Virus Shedding  
The body's dangerous defenders 期刊论文
, 2020, 卷号: 367, 期号: 6482
作者:  Leslie M.
收藏  |  浏览/下载：39/0  |  提交时间：2020/07/28
alvelestat  avacopan  chemokine receptor CXCR2  danirixin  leukocyte elastase  n [2 (2,3 difluorobenzylthio) 6 (2,3 dihydroxy 1 methylpropoxy) 4 pyrimidinyl] 1 azetidinesulfonamide  nemiralisib  simvastatin  leukocyte elastase inhibitor  antimicrobial activity  apoptosis  cell  enzyme activity  physiological response  ANCA associated vasculitis  Article  autoimmune disease  autoimmunity  bacterial pneumonia  bactericidal activity  bronchiolitis obliterans  drug targeting  extracellular matrix  extracellular trap  hematopoietic stem cell transplantation  human  immunity  immunocompetent cell  infection  inflammation  lung disease  neutrophil  neutrophil chemotaxis  nonhuman  priority journal  risk factor  sepsis  single cell RNA seq  autoimmune disease  chronic obstructive lung disease  clinical trial (topic)  drug effect  enzymology  immunology  lung tumor  neutrophil  Autoimmune Diseases  Clinical Trials as Topic  Humans  Lung Neoplasms  Neutrophils  Proteinase Inhibitory Proteins, Secretory  Pulmonary Disease, Chronic Obstructive  
A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者:  Wu Y.;  Wang F.;  Shen C.;  Peng W.;  Li D.;  Zhao C.;  Li Z.;  Li S.;  Bi Y.;  Yang Y.;  Gong Y.;  Xiao H.;  Fan Z.;  Tan S.;  Wu G.;  Tan W.;  Lu X.;  Fan C.;  Wang Q.;  Liu Y.;  Zhang C.;  Qi J.;  Gao G.F.;  Gao F.;  Liu L.
收藏  |  浏览/下载：33/0  |  提交时间：2020/07/28
Coronavirus  angiotensin converting enzyme 2  coronavirus spike glycoprotein  dipeptidyl carboxypeptidase  epitope  monoclonal antibody  neutralizing antibody  virus antibody  virus receptor  animal  chemistry  Coronavirus infection  disease model  human  immunology  isolation and purification  lung  mouse  pandemic  protein domain  serodiagnosis  virology  virus load  virus pneumonia  Animals  Antibodies, Monoclonal  Antibodies, Neutralizing  Antibodies, Viral  Coronavirus Infections  Disease Models, Animal  Humans  Immunodominant Epitopes  Lung  Mice  Neutralization Tests  Pandemics  Peptidyl-Dipeptidase A  Pneumonia, Viral  Protein Domains  Receptors, Virus  Spike Glycoprotein, Coronavirus  Viral Load  
A rampage through the body 期刊论文
, 2020, 卷号: 368, 期号: 6489
作者:  Wadman M.;  Couzin-Frankel J.;  Kaiser J.;  Matacic C.
收藏  |  浏览/下载：32/0  |  提交时间：2020/07/28
blood  brain  brain drain  cell organelle  immune response  infectious disease  protein  viral disease  Article  clinical feature  coronavirus disease 2019  disease severity  disease transmission  human  mortality rate  patient care  patient risk  priority journal  risk factor  Betacoronavirus  blood vessel  brain  Coronavirus infection  female  lung  male  middle aged  multiple organ failure  pandemic  pathogenicity  pathology  virology  virus entry  virus pneumonia  Betacoronavirus  Blood Vessels  Brain  Coronavirus Infections  Female  Humans  Lung  Male  Middle Aged  Multiple Organ Failure  Pandemics  Pneumonia, Viral  Virus Internalization