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Unanchored ubiquitin chain sustains RIG-I-induced interferon-I activation and controls selective gene expression 期刊论文
Science Bulletin, 2021, 卷号: 66, 期号: 8
作者:  Xian H.;  Huang W.;  Sun T.;  Yang S.;  Zhang C.;  Wang J.;  Zhang Y.;  Cui J.
收藏  |  浏览/下载:33/0  |  提交时间:2021/09/01
Antiviral immunity  Cellular homeostasis  RIG-I  Type I interferon  Ubiquitination  Unanchored ubiquitin chains  
Restriction of exogenous DNA expression by SAMHD1 期刊论文
Science Bulletin, 2020, 卷号: 65, 期号: 7
作者:  Gu C.;  Ming L.;  Fang Y.;  Liu X.;  Zhang J.;  Zelinskyy G.;  Deng Q.;  Liu J.;  Xie Y.
收藏  |  浏览/下载:16/0  |  提交时间:2021/09/01
Exogenous DNA  Hepatitis B virus  Interferon regulatory factor-1  SAMHD1  
Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells 期刊论文
, 2020, 卷号: 368, 期号: 6494
作者:  Zhou Z.;  He H.;  Wang K.;  Shi X.;  Wang Y.;  Su Y.;  Wang Y.;  Li D.;  Liu W.;  Zhang Y.;  Shen L.;  Han W.;  Shen L.;  Ding J.;  Shao F.
收藏  |  浏览/下载:32/0  |  提交时间:2020/07/28
cell  cell component  cytology  enzyme  enzyme activity  gene expression  immunity  tumor  Mus  gamma interferon  granzyme  GSDMB protein, human  GZMA protein, human  pore forming cytotoxic protein  tumor protein  animal  Bagg albino mouse  chemistry  cytotoxic T lymphocyte  enzymology  genetics  HEK293 cell line  human  immunology  metabolism  mouse  natural killer cell  neoplasm  pathology  protein degradation  protein domain  pyroptosis  transgenic mouse  Animals  Granzymes  HEK293 Cells  Humans  Interferon-gamma  Killer Cells, Natural  Mice  Mice, Inbred BALB C  Mice, Transgenic  Neoplasm Proteins  Neoplasms  Pore Forming Cytotoxic Proteins  Protein Domains  Proteolysis  Pyroptosis  T-Lymphocytes, Cytotoxic  
VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance 期刊论文
, 2020, 卷号: 367, 期号: 6475
作者:  ElTanbouly M.A.;  Zhao Y.;  Nowak E.;  Li J.;  Schaafsma E.;  Le Mercier I.;  Ceeraz S.;  Lines J.L.;  Peng C.;  Carriere C.;  Huang X.;  Day M.;  Koehn B.;  Lee S.W.;  Morales M.S.;  Hogquist K.A.;  Jameson S.C.;  Mueller D.;  Rothstein J.;  Blazar B.R.;  Cheng C.;  Noelle R.J.
收藏  |  浏览/下载:56/0  |  提交时间:2020/07/28
cell protein  interferon  kruppel like factor 2  T lymphocyte receptor  unclassified drug  V type immunoglobulin domain containing suppressor of T cell activation protein  B7 antigen  Dies1 protein, mouse  lymphocyte antigen receptor  membrane protein  monoclonal antibody  VSIR protein, human  biological development  cell  gene expression  heterogeneity  homeostasis  immune response  immunity  tolerance  acute graft versus host disease  animal cell  animal experiment  animal model  Article  CD4+ T lymphocyte  cell death  cell expansion  cell fate  cell heterogeneity  cell loss  cell survival  controlled study  female  gene  gene deletion  homeostasis  immunological tolerance  in vivo study  long term survival  male  mouse  nonhuman  phenotype  priority journal  protein expression  protein function  rheumatoid arthritis  RNA sequencing  systemic lupus erythematosus  T lymphocyte  T lymphocyte activation  T lymphocyte subpopulation  TCR gene  upregulation  VISTA gene  animal  C57BL mouse  genetics  immunological tolerance  immunology  knockout mouse  lymphocyte activation  physiology  T lymphocyte  Mus  Animals  Antibodies, Monoclonal  B7 Antigens  Lymphocyte Activation  Membrane Proteins  Mice  Mice, Inbred C57BL  Mice, Knockout  Peripheral Tolerance  Receptors, Antigen, T-Cell  T-Lymphocytes  
Pulmonary surfactant-biomimetic nanoparticles potentiate heterosubtypic influenza immunity 期刊论文
, 2020, 卷号: 367, 期号: 6480
作者:  Wang J.;  Li P.;  Yu Y.;  Fu Y.;  Jiang H.;  Lu M.;  Sun Z.;  Jiang S.;  Lu L.;  Wu M.X.
收藏  |  浏览/下载:43/0  |  提交时间:2020/07/28
2',3' cyclic guanosine monophosphate adenosine monophosphate  influenza vaccine  interferon  nanoparticle  pulmonary surfactant biomimetic nanoparticle  purine nucleotide  surfactant protein A  surfactant protein D  unclassified drug  cell  drug resistance  immune response  immunity  induced response  influenza  nanoparticle  rodent  surfactant  vaccine  animal cell  animal experiment  animal model  animal tissue  Article  CD8+ T lymphocyte  cellular immunity  controlled study  cross protection  cytokine response  drug efficacy  drug safety  drug synthesis  female  human  humoral immunity  hydrophilicity  immune response  immunopathology  immunosurveillance  influenza  innate immunity  lung alveolus epithelium cell  lung alveolus macrophage  mouse  Mustela putorius furo  nanoencapsulation  nonhuman  priority journal  Mus  Mustela  
Cultivating fungal research 期刊论文
, 2020, 卷号: 368, 期号: 6489
作者:  Kong H.H.;  Segre J.A.
收藏  |  浏览/下载:69/0  |  提交时间:2020/07/28
amphotericin B  dectin 1  echinocandin  fluconazole  interleukin 17  bacterium  fungal disease  fungus  immune system  mutualism  pathogen  antifungal resistance  Article  autoimmune disease  bloodstream infection  Candida albicans  Candida auris  CD4+ T lymphocyte  commensalism  fungal colonization  fungus transmission  host fungus interaction  immune deficiency  interferon production  multidrug resistance  mycosis  nonhuman  opportunistic infection  pancreas adenocarcinoma  priority journal  Th17 cell