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VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance
期刊论文
, 2020, 卷号: 367, 期号: 6475
作者:
ElTanbouly M.A.
;
Zhao Y.
;
Nowak E.
;
Li J.
;
Schaafsma E.
;
Le Mercier I.
;
Ceeraz S.
;
Lines J.L.
;
Peng C.
;
Carriere C.
;
Huang X.
;
Day M.
;
Koehn B.
;
Lee S.W.
;
Morales M.S.
;
Hogquist K.A.
;
Jameson S.C.
;
Mueller D.
;
Rothstein J.
;
Blazar B.R.
;
Cheng C.
;
Noelle R.J.
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2020/07/28
cell protein
interferon
kruppel like factor 2
T lymphocyte receptor
unclassified drug
V type immunoglobulin domain containing suppressor of T cell activation protein
B7 antigen
Dies1 protein, mouse
lymphocyte antigen receptor
membrane protein
monoclonal antibody
VSIR protein, human
biological development
cell
gene expression
heterogeneity
homeostasis
immune response
immunity
tolerance
acute graft versus host disease
animal cell
animal experiment
animal model
Article
CD4+ T lymphocyte
cell death
cell expansion
cell fate
cell heterogeneity
cell loss
cell survival
controlled study
female
gene
gene deletion
homeostasis
immunological tolerance
in vivo study
long term survival
male
mouse
nonhuman
phenotype
priority journal
protein expression
protein function
rheumatoid arthritis
RNA sequencing
systemic lupus erythematosus
T lymphocyte
T lymphocyte activation
T lymphocyte subpopulation
TCR gene
upregulation
VISTA gene
animal
C57BL mouse
genetics
immunological tolerance
immunology
knockout mouse
lymphocyte activation
physiology
T lymphocyte
Mus
Animals
Antibodies, Monoclonal
B7 Antigens
Lymphocyte Activation
Membrane Proteins
Mice
Mice, Inbred C57BL
Mice, Knockout
Peripheral Tolerance
Receptors, Antigen, T-Cell
T-Lymphocytes
The evolutionary dynamics and fitness landscape of clonal hematopoiesis
期刊论文
, 2020, 卷号: 367, 期号: 6485
作者:
Watson C.J.
;
Papula A.L.
;
Poon G.Y.P.
;
Wong W.H.
;
Young A.L.
;
Druley T.E.
;
Fisher D.S.
;
Blundell J.R.
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/28
DNA methyltransferase 3A
blood
cancer
evolutionary biology
fitness
gene expression
genetic drift
hematology
mutation
pathogenicity
acute myeloid leukemia
age distribution
allele
Article
cancer risk
cell expansion
cell population
clonal hematopoiesis
epigenetics
gene mutation
genetic variability
hematological parameters
hematopoiesis
hematopoietic stem cell
human
molecular evolution
mutational analysis
nonhuman
priority journal
single nucleotide polymorphism
somatic mutation
stem cell self-renewal
MRNA destabilization by BTG1 and BTG2 maintains T cell quiescence
期刊论文
, 2020, 卷号: 367, 期号: 6483
作者:
Hwang S.S.
;
Lim J.
;
Yu Z.
;
Kong P.
;
Sefik E.
;
Xu H.
;
Harman C.C.D.
;
Kim L.K.
;
Lee G.R.
;
Li H.-B.
;
Flavell R.A.
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/28
CD69 antigen
chemokine receptor CCR7
epidermal growth factor receptor 2
Hermes antigen
interleukin 2 receptor alpha
interleukin 2 receptor gamma
interleukin 7 receptor
kruppel like factor 2
messenger RNA
polyadenylic acid
T lymphocyte receptor
transcription factor FKHR
transcriptome
biodegradation
cell component
RNA
adenylation
Article
BTG1 gene
BTG2 gene
Ccr7 gene
CD4+ T lymphocyte
CD8+ T lymphocyte
cell differentiation
cell expansion
cell maturation
cell migration
cell proliferation
cell size
cell specificity
cell survival
controlled study
CRISPR-CAS9 system
flow cytometry
gene
gene control
gene expression
gene function
gene identification
immunoprecipitation
in vitro study
in vivo study
memory T lymphocyte
nonhuman
phylogenetic tree
priority journal
RNA degradation
RNA sequencing
S1pr1 gene
Sell gene
spleen
T lymphocyte
T lymphocyte activation
tail length (comet assay)
thymus
upregulation
Hope for hematological diseases
期刊论文
, 2020, 卷号: 367, 期号: 6483
作者:
Wilkinson A.C.
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/07/28
fibronectin
polyvinyl alcohol
serum albumin
stem cell factor
thrombopoietin
blood
disease incidence
disease treatment
laboratory method
medicine
public health
Article
cell differentiation
cell self-renewal
chemotherapy
CRISPR-CAS9 system
ex vivo study
gene editing
gene therapy
genotoxicity
graft versus host reaction
hematologic disease
hematopoiesis
hematopoietic stem cell transplantation
human
morbidity
mortality
multipotent stem cell
nonhuman
priority journal
radiotherapy
stem cell culture
stem cell expansion
Changes in Moisture Flux over the Tibetan Plateau during 1979-2011 and Possible Mechanisms
期刊论文
JOURNAL OF CLIMATE, 2014, 卷号: 27, 期号: 5
作者:
Gao, Yanhong
;
Cuo, Lan
;
Zhang, Yongxin
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/06/21
ATMOSPHERIC HEAT-SOURCE
CLIMATE-CHANGE
HYDROLOGICAL CYCLE
WEAKENING TREND
HADLEY-CELL
ERA-INTERIM
PRECIPITATION
HYDROCLIMATE
EXPANSION
RANGE