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| Human CNS barrier-forming organoids with cerebrospinal fluid production 期刊论文 , 2020, 卷号: 369, 期号: 6500 作者: Pellegrini L.; Bonfio C.; Chadwick J.; Begum F.; Skehel M.; Lancaster M.A. 收藏  |  浏览/下载:39/0  |  提交时间:2020/07/28 blood brain barrier cell culture technique cerebrospinal fluid choroid plexus gene expression profiling human metabolism organoid physiology protein cerebrospinal fluid level proteomics single cell analysis Blood-Brain Barrier Cell Culture Techniques Cerebrospinal Fluid Cerebrospinal Fluid Proteins Choroid Plexus Gene Expression Profiling Humans Organoids Proteomics Single-Cell Analysis |
| Correlative three-dimensional super-resolution and block-face electron microscopy of whole vitreously frozen cells 期刊论文 , 2020, 卷号: 367, 期号: 6475 作者: Hoffman D.P.; Shtengel G.; Xu C.S.; Campbell K.R.; Freeman M.; Wang L.; Milkie D.E.; Pasolli H.A.; Iyer N.; Bogovic J.A.; Stabley D.R.; Shirinifard A.; Pang S.; Peale D.; Schaefer K.; Pomp W.; Chang C.-L.; Lippincott-Schwartz J.; Kirchhausen T.; Solecki D.J.; Betzig E.; Hess H.F. 收藏  |  浏览/下载:50/0  |  提交时间:2020/07/28 cell compartmentalization cryopreservation electron microscopy image resolution protein three-dimensional modeling ultrastructure article chromatin electron microscopy endoplasmic reticulum genetic transcription human cell mammal cell nerve cell culture protein domain ultrastructure whole cell workflow animal cell adhesion cells Chlorocebus aethiops cryoelectron microscopy CV-1 cell line fluorescence microscopy freezing HeLa cell line human mouse procedures three-dimensional imaging tumor cell line ultrastructure Mammalia Animals Cell Adhesion Cell Line, Tumor Cells Chlorocebus aethiops COS Cells Cryoelectron Microscopy Freezing HeLa Cells Humans Imaging, Three-Dimensional Mice Microscopy, Fluorescence |
| Meet the psychobiome 期刊论文 , 2020, 卷号: 368, 期号: 6491 作者: Pennisi E. 收藏  |  浏览/下载:29/0  |  提交时间:2020/07/28 4 aminobutyric acid antibiotic agent dopamine kynurenine probiotic agent queuine serotonin psychotropic agent bacterium biome drug microbial activity nervous system disorder allergy Alzheimer disease antimicrobial therapy anxiety disorder archaeon Article autism bacterium culture Bacteroides blood brain barrier blood vessel brain disease clinical effectiveness constipation depression drug use enteroendocrine cell enteropathy entrepreneurship epilepsy fecal microbiota transplantation feces analysis Food and Drug Administration fungus genomics human insomnia intestine flora irritable colon mammal cell microbiology microbiome nerve cell nervous system nervous system development neurologic disease nonhuman obesity pain threshold Parkinson disease physician priority journal psychobiome psychological aspect psychological well-being schizophrenia scientist United States vagus nerve virus animal bacterium chemistry drug development intestine flora isolation and purification metabolism microbiology physiology procedures Animals Bacteria Drug Discovery Gastrointestinal Microbiome Humans Nervous System Diseases Psychotropic Drugs |
| Seed osmopriming with PEG solutions in seeds of three infraspecific taxa of Pinus nigra: Impacts on germination, mitosis and nuclear DNA 期刊论文 , 2020, 卷号: 456 作者: Carvalho A.; Gaivão I.; Lima-Brito J. 收藏  |  浏览/下载:18/0  |  提交时间:2020/07/28 Cell culture Cultivation DNA Electrophoresis Needles Osmosis Reforestation Value engineering Black pines Cytogenetics Germination Mitosis Osmopriming Single cell gel electrophoresis Seed coniferous forest cytogenetics DNA ecological impact electrokinesis germination juvenile performance assessment phenology seed spatial distribution Cultivation Electrophoresis Needles Nucleic Acids Osmosis Reforestation Portugal Pinus nigra |
| SARS-CoV-2 productively infects human gut enterocytes 期刊论文 , 2020, 卷号: 369, 期号: 6499 作者: Lamers M.M.; Beumer J.; van der Vaart J.; Knoops K.; Puschhof J.; Breugem T.I.; Ravelli R.B.G.; Paul van Schayck J.; Mykytyn A.Z.; Duimel H.Q.; van Donselaar E.; Riesebosch S.; Kuijpers H.J.H.; Schipper D.; van de Wetering W.J.; de Graaf M.; Koopmans M.; Cuppen E.; Peters P.J.; Haagmans B.L.; Clevers H. 收藏  |  浏览/下载:36/0  |  提交时间:2020/07/28 angiotensin converting enzyme 2 dipeptidyl carboxypeptidase messenger RNA virus receptor Betacoronavirus cell culture technique cell differentiation cell lineage cell proliferation culture medium gene expression genetics human ileum intestine cell lung male metabolism organoid physiology respiratory mucosa SARS coronavirus ultrastructure virology virus replication Betacoronavirus Cell Culture Techniques Cell Differentiation Cell Lineage Cell Proliferation Culture Media Enterocytes Gene Expression Humans Ileum Lung Male Organoids Peptidyl-Dipeptidase A Receptors, Virus Respiratory Mucosa RNA, Messenger SARS Virus Virus Replication |
| Liquid droplets in the skin 期刊论文 , 2020, 卷号: 367, 期号: 6483 作者: Rai A.; Pelkmans L. 收藏  |  浏览/下载:27/0  |  提交时间:2020/07/28 keratin keratohyalin profilaggrin filaggrin keratohyalin polyadenylic acid binding protein droplet membrane physiological response separation skin cell component cell organelle physiology protein acidification Article cell culture cell differentiation cell protection cell structure epidermis human keratinocyte nonhuman permeability barrier pH phase separation priority journal protein aggregation protein expression protein phosphorylation protein processing skin cell skin permeability stoichiometry stratum corneum tissue differentiation liquid crystal skin surface property calcium cell level cell compartmentalization degenerative disease environmental stress epidermis cell ichthyosis vulgaris iquid liquid phase separation keratinocyte macromolecular crowding protein cross linking protein degradation Short Survey signal transduction Liquid Crystals Skin Surface Properties |
| Hope for hematological diseases 期刊论文 , 2020, 卷号: 367, 期号: 6483 作者: Wilkinson A.C. 收藏  |  浏览/下载:41/0  |  提交时间:2020/07/28 fibronectin polyvinyl alcohol serum albumin stem cell factor thrombopoietin blood disease incidence disease treatment laboratory method medicine public health Article cell differentiation cell self-renewal chemotherapy CRISPR-CAS9 system ex vivo study gene editing gene therapy genotoxicity graft versus host reaction hematologic disease hematopoiesis hematopoietic stem cell transplantation human morbidity mortality multipotent stem cell nonhuman priority journal radiotherapy stem cell culture stem cell expansion |
| Genetically targeted chemical assembly of functional materials in living cells, tissues, and animals 期刊论文 , 2020, 卷号: 367, 期号: 6484 作者: Liu J.; Kim Y.S.; Richardson C.E.; Tom A.; Ramakrishnan C.; Birey F.; Katsumata T.; Chen S.; Wang C.; Wang X.; Joubert L.-M.; Jiang Y.; Wang H.; Fenno L.E.; Tok J.B.-H.; Paşca S.P.; Shen K.; Bao Z.; Deisseroth K. 收藏  |  浏览/下载:50/0  |  提交时间:2020/07/28 poly(3,4 ethylenedioxythiophene) polyaniline polymer unclassified drug 3-nitro-o-phenylenediamine aniline aniline derivative ascorbate peroxidase nitro derivative phenylenediamine derivative polymer anatomy genetic engineering membrane physiological response polymer animal cell Article biocompatibility brain nerve cell brain slice Caenorhabditis elegans cell membrane cell viability controlled study genetic procedures genetically targeted chemical assemby hippocampal neuronal culture human human cell in vivo study nerve cell membrane nonhuman polymerization priority journal rat synthesis action potential animal cell culture cell survival chemistry electric conductivity enzymology genetic engineering genetic transduction genetics HEK293 cell line hippocampus membrane potential metabolism motoneuron mouse muscle cell nerve cell patch clamp technique physiology Animalia Action Potentials Aniline Compounds Animals Ascorbate Peroxidases Caenorhabditis elegans Cell Membrane Cell Survival Cells, Cultured Electric Conductivity Genetic Engineering HEK293 Cells Hippocampus Humans Membrane Potentials Mice Motor Neurons Muscle Cells Neurons Nitro Compounds Patch-Clamp Techniques Phenylenediamines Polymers Rats Transduction, Genetic |
| Basic and Applied Aspects of Biotechnology 专著 :Springer Singapore, Springer, 2017 作者: Sengupta Manjistha; Prakash Jaya; Tripathy Baishnab Charan; Gupta Varsha 收藏  |  浏览/下载:60/0  |  提交时间:2020/03/25 Environment. Biotechnology. Cell culture. Regenerative medicine. Tissue engineering. Microbial genetics. Microbial genomics. Environmental engineering. Environment. Environmental Engineering/Biotechnology. Biotechnology. Microbial Genetics and Genomics. Cell Culture. Regenerative Medicine/Tissue Engineering. |