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CFLIPL protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation 期刊论文
, 2020, 卷号: 367, 期号: 6484
作者:  Muendlein H.I.;  Jetton D.;  Connolly W.M.;  Eidell K.P.;  Magri Z.;  Smirnova I.;  Poltorak A.
收藏  |  浏览/下载:48/0  |  提交时间:2020/07/28
FLICE inhibitory protein  interleukin 1beta  lipopolysaccharide  messenger RNA  succinate dehydrogenase (ubiquinone)  Casp1 protein, mouse  caspase 8  Cflar protein, mouse  cryopyrin  FLICE inhibitory protein  IL1B protein, mouse  inflammasome  interleukin 1beta  interleukin 1beta converting enzyme  lipopolysaccharide  succinate dehydrogenase (ubiquinone)  cell  enzyme activity  inhibition  maturation  protein  animal cell  animal experiment  Article  bone marrow derived macrophage  cell death  cell protection  complex formation  controlled study  cytokine release  in vitro study  inflammation  mouse  nonhuman  priority journal  protein analysis  protein degradation  protein function  protein interaction  pyroptosis  animal  gene knockdown  genetics  immunology  macrophage  macrophage activation  metabolism  physiology  Murinae  Animals  CASP8 and FADD-Like Apoptosis Regulating Protein  Caspase 1  Caspase 8  Electron Transport Complex II  Gene Knockdown Techniques  Inflammasomes  Interleukin-1beta  Lipopolysaccharides  Macrophage Activation  Macrophages  Mice  NLR Family, Pyrin Domain-Containing 3 Protein  Pyroptosis  
N6-methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription 期刊论文
, 2020, 卷号: 367, 期号: 6477
作者:  Liu J.;  Dou X.;  Chen C.;  Chen C.;  Liu C.;  Michelle Xu M.;  Zhao S.;  Shen B.;  Gao Y.;  Han D.;  He C.
收藏  |  浏览/下载:14/0  |  提交时间:2020/07/28
6 n methyladenosine  chromosome associated regulatory RNA  enhancer RNA  messenger RNA  promoter associated RNA  repeat RNA  RNA  unclassified drug  cell component  chemical compound  chromosome  methylation  RNA  animal cell  Article  biodegradation  chemical modification  chromatin  controlled study  demethylation  embryo  embryonic stem cell  exosome  methylation  METTL3 gene  mouse  nonhuman  nuclear degradation  priority journal  transcription regulation  Ythdc1 gene  
TTC5 mediates autoregulation of tubulin via mRNA degradation 期刊论文
, 2020, 卷号: 367, 期号: 6473
作者:  Lin Z.;  Gasic I.;  Chandrasekaran V.;  Peters N.;  Shao S.;  Mitchison T.J.;  Hegde R.S.
收藏  |  浏览/下载:26/0  |  提交时间:2020/07/28
messenger RNA  mutant protein  polypeptide  recombinant protein  regulator protein  tetratricopeptide protein 5  tubulin  unclassified drug  biodegradation  chromosome  peptide  protein  RNA  amino terminal sequence  animal cell  Article  autoregulation  binding site  chromosome segregation  controlled study  cryoelectron microscopy  genetic code  human  human cell  Leporidae  mitosis  molecular model  nonhuman  priority journal  protein analysis  protein binding  protein interaction  protein structure  reticulocyte  ribosome  RNA degradation  RNA translation  tubulin gene  
MRNA destabilization by BTG1 and BTG2 maintains T cell quiescence 期刊论文
, 2020, 卷号: 367, 期号: 6483
作者:  Hwang S.S.;  Lim J.;  Yu Z.;  Kong P.;  Sefik E.;  Xu H.;  Harman C.C.D.;  Kim L.K.;  Lee G.R.;  Li H.-B.;  Flavell R.A.
收藏  |  浏览/下载:28/0  |  提交时间:2020/07/28
CD69 antigen  chemokine receptor CCR7  epidermal growth factor receptor 2  Hermes antigen  interleukin 2 receptor alpha  interleukin 2 receptor gamma  interleukin 7 receptor  kruppel like factor 2  messenger RNA  polyadenylic acid  T lymphocyte receptor  transcription factor FKHR  transcriptome  biodegradation  cell component  RNA  adenylation  Article  BTG1 gene  BTG2 gene  Ccr7 gene  CD4+ T lymphocyte  CD8+ T lymphocyte  cell differentiation  cell expansion  cell maturation  cell migration  cell proliferation  cell size  cell specificity  cell survival  controlled study  CRISPR-CAS9 system  flow cytometry  gene  gene control  gene expression  gene function  gene identification  immunoprecipitation  in vitro study  in vivo study  memory T lymphocyte  nonhuman  phylogenetic tree  priority journal  RNA degradation  RNA sequencing  S1pr1 gene  Sell gene  spleen  T lymphocyte  T lymphocyte activation  tail length (comet assay)  thymus  upregulation