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Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations 期刊论文
, 2020, 卷号: 367, 期号: 6478
作者:  Wilmes S.;  Hafer M.;  Vuorio J.;  Tucker J.A.;  Winkelmann H.;  Löchte S.;  Stanly T.A.;  Pulgar Prieto K.D.;  Poojari C.;  Sharma V.;  Richter C.P.;  Kurre R.;  Hubbard S.R.;  Christopher Garcia K.;  Moraga I.;  Vattulainen I.;  Hitchcock I.S.;  Piehler J.
收藏  |  浏览/下载：49/0  |  提交时间：2020/07/28
cytokine receptor  homodimer  Janus kinase 2  ligand  oncoprotein  cancer  enzyme  enzyme activity  membrane  molecular analysis  mutation  protein  activation analysis  Article  cell membrane  computer model  controlled study  dimerization  fluorescence microscopy  gene mutation  HeLa cell line  molecular dynamics  mutant  oncogene  priority journal  protein domain  protein interaction  quantitative analysis  signal transduction  
Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice 期刊论文
, 2020, 卷号: 368, 期号: 6491
作者:  Guthrie L.M.;  Soma S.;  Yuan S.;  Silva A.;  Zulkifli M.;  Snavely T.C.;  Greene H.F.;  Nunez E.;  Lynch B.;  de Ville C.;  Shanbhag V.;  Lopez F.R.;  Acharya A.;  Petris M.J.;  Kim B.-E.;  Gohil V.M.;  Sacchettini J.C.
收藏  |  浏览/下载：40/0  |  提交时间：2020/07/28
copper  copper zinc superoxide dismutase  cytochrome c oxidase  dopamine beta monooxygenase  elesclomol  monophenol monooxygenase  protein lysine 6 oxidase  copper  cytochrome c oxidase  elesclomol  hydrazine derivative  copper  cytochrome  enzyme  enzyme activity  mitochondrion  mortality  mutation  pathology  rodent  survival  animal cell  animal experiment  animal model  animal tissue  Article  cohort analysis  controlled study  disease severity  drug mechanism  Golgi complex  H9c2(2-1) cell line  in vivo study  male  Menkes syndrome  mitochondrial dynamics  mortality rate  mouse  nerve degeneration  nonhuman  priority journal  secretory pathway  survival rate  animal  brain  cell line  degenerative disease  disease model  drug effect  genetics  knockout mouse  Menkes syndrome  metabolism  mitochondrion  pathology  rat  transport at the cellular level  Murinae  Mus  Animals  Biological Transport  Brain  Cell Line  Copper  Copper Transporter 1  Disease Models, Animal  Electron Transport Complex IV  Hydrazines  Male  Menkes Kinky Hair Syndrome  Mice  Mice, Knockout  Mitochondria  Neurodegenerative Diseases  Rats  
Golgi-derived PI(4)P-containing vesicles drive late steps of mitochondrial division 期刊论文
, 2020, 卷号: 367, 期号: 6484
作者:  Nagashima S.;  Tábara L.-C.;  Tilokani L.;  Paupe V.;  Anand H.;  Pogson J.H.;  Zunino R.;  McBride H.M.;  Prudent J.
收藏  |  浏览/下载：39/0  |  提交时间：2020/07/28
adenosine diphosphate ribosylation factor 1  dynamin related protein 1  mitochondrial protein  phosphatidylinositol 4 kinase IIIbeta  phosphatidylinositol 4 phosphate  phosphatidylinositol kinase  unclassified drug  adenosine diphosphate ribosylation factor 1  ARF1 protein, human  DNM1L protein, human  dynamin  phosphatidylinositol 4-phosphate  phosphatidylinositol kinase  polyphosphoinositide  cell component  cell organelle  chemical compound  enzyme  enzyme activity  mitochondrion  protein  Article  controlled study  COS-7 cell line  endoplasmic reticulum  fibroblast  gene silencing  HeLa cell line  human  human cell  membrane microdomain  mitochondrial division  mitochondrial dynamics  mitochondrial scission  priority journal  protein localization  trans Golgi network  U2OS cell line  animal  cell line  Chlorocebus aethiops  CV-1 cell line  genetics  metabolism  mitochondrial membrane  mitochondrion  RNA interference  trans Golgi network  ultrastructure  Mammalia  1-Phosphatidylinositol 4-Kinase  ADP-Ribosylation Factor 1  Animals  Cell Line  Chlorocebus aethiops  COS Cells  Dynamins  Endoplasmic Reticulum  HeLa Cells  Humans  Membrane Microdomains  Mitochondria  Mitochondrial Dynamics  Mitochondrial Membranes  Phosphatidylinositol Phosphates  RNA Interference  trans-Golgi Network  
Interleukin-13 drives metabolic conditioning of muscle to endurance exercise 期刊论文
, 2020, 卷号: 368, 期号: 6490
作者:  Knudsen N.H.;  Stanya K.J.;  Hyde A.L.;  Chalom M.M.;  Alexander R.K.;  Liou Y.-H.;  Starost K.A.;  Gangl M.R.;  Jacobi D.;  Liu S.;  Sopariwala D.H.;  Fonseca-Pereira D.;  Li J.;  Hu F.B.;  Garrett W.S.;  Narkar V.A.;  Ortlund E.A.;  Kim J.H.;  Paton C.M.;  Cooper J.A.;  Lee C.-H.
收藏  |  浏览/下载：51/0  |  提交时间：2020/07/28
glucose  interleukin 13  interleukin 13 receptor alpha1  interleukin 6  STAT3 protein  fatty acid  glycogen  interleukin 13  interleukin 13 receptor alpha1  STAT3 protein  Stat3 protein, mouse  fatty acid  metabolism  muscle  oxidation  physiological response  protein  respiration  aerobic exercise  animal cell  animal experiment  animal tissue  Article  C2C12 cell line  cohort analysis  controlled study  endurance training  energy metabolism  ex vivo study  exercise intensity  female  gastrocnemius muscle  glucose tolerance  human  in vitro study  male  mitochondrial biogenesis  mitochondrial dynamics  mitochondrial respiration  mouse  muscle metabolism  muscle mitochondrion  nonhuman  obesity  priority journal  protein blood level  protein expression  running  sedentary lifestyle  signal transduction  treadmill exercise  adaptation  animal  blood  C57BL mouse  cell line  endurance  genetics  glucose blood level  immunology  knockout mouse  metabolism  myoblast  oxidation reduction reaction  skeletal muscle  Mus  Adaptation, Physiological  Animals  Blood Glucose  Cell Line  Fatty Acids  Female  Glycogen  Humans  Interleukin-13  Interleukin-13 Receptor alpha1 Subunit  Male  Mice  Mice, Inbred C57BL  Mice, Knockout  Mitochondria, Muscle  Muscle, Skeletal  Myoblasts  Oxidation-Reduction  Physical Conditioning, Animal  Physical Endurance  Running  STAT3 Transcription Factor  
Sequencing metabolically labeled transcripts in single cells reveals mRNA turnover strategies 期刊论文
, 2020, 卷号: 367, 期号: 6483
作者:  Battich N.;  Beumer J.;  De Barbanson B.;  Krenning L.;  Baron C.S.;  Tanenbaum M.E.;  Clevers H.;  Van Oudenaarden A.
收藏  |  浏览/下载：228/0  |  提交时间：2020/07/28
messenger RNA  dyes, reagents, indicators, markers and buffers  messenger RNA  uridine  cell component  differentiation  gene expression  metabolism  RNA  turnover  Article  cell cycle  cell differentiation  cell metabolism  gene cluster  gene control  gene expression  genetic transcription  human  intestinal stem cell  molecular dynamics  priority journal  regulatory mechanism  RNA sequencing  single cell analysis  animal  chemistry  K-562 cell line  metabolism  mouse  procedures  RNA stability  sequence analysis  single cell analysis  Mammalia  Animals  Humans  Indicators and Reagents  K562 Cells  Mice  RNA Stability  RNA, Messenger  Sequence Analysis, RNA  Single-Cell Analysis  Transcription, Genetic  Uridine  
Past the climate optimum: Recruitment is declining at the world's highest juniper shrublines on the Tibetan Plateau 期刊论文
ECOLOGY, 2019, 卷号: 100, 期号: 2
作者:  Lu, Xiaoming;  Liang, Eryuan;  Wang, Yafeng;  Babst, Flurin;  Leavitt, Steven W.;  Julio Camarero, J.
收藏  |  浏览/下载：47/0  |  提交时间：2022/06/21
TREE-LINE  SEEDLING ESTABLISHMENT  ROCKY-MOUNTAINS  PLANT COMMUNITY  ALPINE TREELINE  DYNAMICS  TUNDRA  FOREST  REGENERATION  TEMPERATURE  
Research advances in disturbance and ecological processes of the treeline ecotone 期刊论文
CHINESE SCIENCE BULLETIN-CHINESE, 2019, 卷号: 64, 期号: 16
作者:  Wang, Yafeng;  Liang, Eryuan
收藏  |  浏览/下载：20/0  |  提交时间：2022/06/21
SUB-ALPINE FORESTS  CLIMATE-CHANGE  TIBETAN PLATEAU  QILIAN MOUNTAINS  SWISS ALPS  LINE  DYNAMICS  WIND  REGENERATION  SUCCESSION  
Impact of plot shape and size on the evaluation of treeline dynamics in the Tibetan Plateau 期刊论文
TREES-STRUCTURE AND FUNCTION, 2016, 卷号: 30, 期号: 4
作者:  Wang, Yafeng;  Zhu, Haifeng;  Liang, Eryuan;  Julio Camarero, J.
收藏  |  浏览/下载：21/0  |  提交时间：2022/06/21
CLIMATE-CHANGE  NORTHWESTERN CHINA  ALPINE TREELINE  LINE DYNAMICS  FOREST GROWTH  VARIABILITY  20TH-CENTURY  MOUNTAINS  RECRUITMENT  EXPANSION  
Species interactions slow warming-induced upward shifts of treelines on the Tibetan Plateau 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2016, 卷号: 113, 期号: 16
作者:  Liang, Eryuan;  Wang, Yafeng;  Piao, Shilong;  Lu, Xiaoming;  Julio Camarero, Jesus;  Zhu, Haifeng;  Zhu, Liping;  Ellison, Aaron M.;  Ciais, Philippe;  Penuelas, Josep
收藏  |  浏览/下载：92/0  |  提交时间：2022/06/21
CLIMATE-CHANGE  TREE-LINE  ALPINE-TREELINE  TEMPERATURE-VARIATIONS  LANDSCAPE DYNAMICS  MOUNTAINS  FOREST  CHINA  RINGS  20TH-CENTURY  
Facilitation stabilizes moisture-controlled alpine juniper shrublines in the central Tibetan Plateau 期刊论文
GLOBAL AND PLANETARY CHANGE, 2015, 卷号: 132
作者:  Wang, Yafeng;  Liang, Eryuan;  Ellison, Aaron M.;  Lu, Xiaoming;  Camarero, J. Julio
收藏  |  浏览/下载：22/0  |  提交时间：2022/06/21
TREE-LINE  CLIMATIC VARIABILITY  DYNAMICS  FOREST  RINGS  EXPANSION  RESPONSES  ECOTONES  PATTERN  TUNDRA