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Disease and fire interact to influence transitions between savanna–forest ecosystems over a multi-decadal experiment 期刊论文
Ecology Letters, 2021, 卷号: 24, 期号: 5
作者:  Pellegrini A.F.A.;  Hein A.M.;  Cavender-Bares J.;  Montgomery R.A.;  Staver A.C.;  Silla F.;  Hobbie S.E.;  Reich P.B.
收藏  |  浏览/下载：51/0  |  提交时间：2021/09/01
Alternative states  fire  forest  forest model  fungal pathogen  plant disease  savanna  tree rings  
Quantifying 25 years of disease-caused declines in Tasmanian devil populations: host density drives spatial pathogen spread 期刊论文
Ecology Letters, 2021, 卷号: 24, 期号: 5
作者:  Cunningham C.X.;  Comte S.;  McCallum H.;  Hamilton D.G.;  Hamede R.;  Storfer A.;  Hollings T.;  Ruiz-Aravena M.;  Kerlin D.H.;  Brook B.W.;  Hocking G.;  Jones M.E.
收藏  |  浏览/下载：44/0  |  提交时间：2021/09/01
Approximate Bayesian Computation  density dependence  devil facial tumour disease  disease spread  emerging infectious disease  host-pathogen  integrated species distribution model  Sarcophilus harrisii  spatial capture-recapture  wildlife disease  
Induction of core symptoms of autism spectrum disorder by in vivo CRISPR/Cas9-based gene editing in the brain of adolescent rhesus monkeys 期刊论文
Science Bulletin, 2021
作者:  Wu S.-H.;  Li X.;  Qin D.-D.;  Zhang L.-H.;  Cheng T.-L.;  Chen Z.-F.;  Nie B.-B.;  Ren X.-F.;  Wu J.;  Wang W.-C.;  Hu Y.-Z.;  Gu Y.-L.;  Lv L.-B.;  Yin Y.;  Hu X.-T.;  Qiu Z.-L.
收藏  |  浏览/下载：31/0  |  提交时间：2021/09/01
Autism spectrum disorders  Disease model  Gene-editing  Nonhuman primate model  
Generation of nonhuman primate retinitis pigmentosa model by in situ knockout of RHO in rhesus macaque retina 期刊论文
Science Bulletin, 2021, 卷号: 66, 期号: 4
作者:  Li S.;  Hu Y.;  Li Y.;  Hu M.;  Wang W.;  Ma Y.;  Cai Y.;  Wei M.;  Yao Y.;  Wang Y.;  Dong K.;  Gu Y.;  Zhao H.;  Bao J.;  Qiu Z.;  Zhang M.;  Hu X.;  Xue T.
收藏  |  浏览/下载：56/0  |  提交时间：2021/09/01
Disease model  Gene editing  Nonhuman primate model  Retinitis pigmentosa  Rhodopsin  SaCas9  
Changes in contact patterns shape the dynamics of the COVID-19 outbreak in China 期刊论文
, 2020, 卷号: 368, 期号: 6498
作者:  Zhang J.;  Litvinova M.;  Liang Y.;  Wang Y.;  Wang W.;  Zhao S.;  Wu Q.;  Merler S.;  Viboud C.;  Vespignani A.;  Ajelli M.;  Yu H.
收藏  |  浏览/下载：31/0  |  提交时间：2020/07/28
adolescent  adult  age  aged  behavior  Betacoronavirus  child  China  communicable disease control  contact examination  Coronavirus infection  disease predisposition  epidemic  female  human  infant  male  middle aged  pandemic  preschool child  school  theoretical model  virus pneumonia  workplace  young adult  Adolescent  Adult  Age Factors  Aged  Behavior  Betacoronavirus  Child  Child, Preschool  China  Communicable Disease Control  Contact Tracing  Coronavirus Infections  Disease Outbreaks  Disease Susceptibility  Female  Humans  Infant  Male  Middle Aged  Models, Theoretical  Pandemics  Pneumonia, Viral  Schools  Workplace  Young Adult  
Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice 期刊论文
, 2020, 卷号: 368, 期号: 6491
作者:  Guthrie L.M.;  Soma S.;  Yuan S.;  Silva A.;  Zulkifli M.;  Snavely T.C.;  Greene H.F.;  Nunez E.;  Lynch B.;  de Ville C.;  Shanbhag V.;  Lopez F.R.;  Acharya A.;  Petris M.J.;  Kim B.-E.;  Gohil V.M.;  Sacchettini J.C.
收藏  |  浏览/下载：36/0  |  提交时间：2020/07/28
copper  copper zinc superoxide dismutase  cytochrome c oxidase  dopamine beta monooxygenase  elesclomol  monophenol monooxygenase  protein lysine 6 oxidase  copper  cytochrome c oxidase  elesclomol  hydrazine derivative  copper  cytochrome  enzyme  enzyme activity  mitochondrion  mortality  mutation  pathology  rodent  survival  animal cell  animal experiment  animal model  animal tissue  Article  cohort analysis  controlled study  disease severity  drug mechanism  Golgi complex  H9c2(2-1) cell line  in vivo study  male  Menkes syndrome  mitochondrial dynamics  mortality rate  mouse  nerve degeneration  nonhuman  priority journal  secretory pathway  survival rate  animal  brain  cell line  degenerative disease  disease model  drug effect  genetics  knockout mouse  Menkes syndrome  metabolism  mitochondrion  pathology  rat  transport at the cellular level  Murinae  Mus  Animals  Biological Transport  Brain  Cell Line  Copper  Copper Transporter 1  Disease Models, Animal  Electron Transport Complex IV  Hydrazines  Male  Menkes Kinky Hair Syndrome  Mice  Mice, Knockout  Mitochondria  Neurodegenerative Diseases  Rats  
Effective containment explains subexponential growth in recent confirmed COVID-19 cases in China 期刊论文
, 2020, 卷号: 368, 期号: 6492
作者:  Maier B.F.;  Brockmann D.
收藏  |  浏览/下载：24/0  |  提交时间：2020/07/28
disease control  disease prevalence  epidemic  health geography  public health  quarantine  symptom  viral disease  China  Coronavirus  basic reproduction number  behavior  Betacoronavirus  China  communicable disease control  contact examination  Coronavirus infection  disease predisposition  epidemic  human  pandemic  quarantine  statistical model  virus pneumonia  Basic Reproduction Number  Behavior  Betacoronavirus  China  Communicable Disease Control  Contact Tracing  Coronavirus Infections  Disease Outbreaks  Disease Susceptibility  Humans  Models, Statistical  Pandemics  Pneumonia, Viral  Quarantine  
Therapeutic targeting of preleukemia cells in a mouse model of NPM1 mutant acute myeloid leukemia 期刊论文
, 2020, 卷号: 367, 期号: 6477
作者:  Uckelmann H.J.;  Kim S.M.;  Wong E.M.;  Hatton C.;  Giovinazzo H.;  Gadrey J.Y.;  Krivtsov A.V.;  Rücker F.G.;  Döhner K.;  McGeehan G.M.;  Levine R.L.;  Bullinger L.;  Vassiliou G.S.;  Armstrong S.A.
收藏  |  浏览/下载：36/0  |  提交时间：2020/07/28
antileukemic agent  methionine  unclassified drug  vtp 50469  biological development  cancer  cell  disease treatment  mutation  numerical model  oral health  acute myeloid leukemia  animal cell  animal experiment  animal model  antineoplastic activity  Article  cell proliferation  cell self-renewal  chromatin  controlled study  drug targeting  gene  gene mutation  leukemia cell  molecularly targeted therapy  mouse  mouse model  nonhuman  NPM1 gene  preleukemia  priority journal  Mus  
A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV 期刊论文
, 2020, 卷号: 368, 期号: 6491
作者:  Yuan M.;  Wu N.C.;  Zhu X.;  Lee C.-C.D.;  So R.T.Y.;  Lv H.;  Mok C.K.P.;  Wilson I.A.
收藏  |  浏览/下载：27/0  |  提交时间：2020/07/28
angiotensin converting enzyme 2  epitope  neutralizing antibody  virus hemagglutinin  virus spike protein  angiotensin converting enzyme 2  coronavirus receptors  coronavirus spike glycoprotein  dipeptidyl carboxypeptidase  epitope  neutralizing antibody  spike glycoprotein, SARS-CoV  spike protein, SARS-CoV-2  virus antibody  virus antigen  virus receptor  antibody  antigen  chemical binding  crystal structure  protein  respiratory disease  viral disease  virus  amino terminal sequence  antibody isolation  antigen binding  antigenicity  Article  binding affinity  binding site  conservation biology  controlled study  coronavirus disease 2019  cross reaction  cryoelectron microscopy  crystal structure  enzyme linked immunosorbent assay  epidemic  glycosylation  human  hydrophobicity  immune response  in vitro study  in vivo study  light chain  nonhuman  priority journal  protein conformation  protein domain  protein interaction  protein localization  protein structure  protein targeting  receptor binding  SARS coronavirus  Severe acute respiratory syndrome coronavirus 2  amino acid sequence  antibody affinity  Betacoronavirus  binding site  chemistry  immunology  metabolism  molecular model  SARS coronavirus  X ray crystallography  Coronavirus  SARS coronavirus  Amino Acid Sequence  Antibodies, Neutralizing  Antibodies, Viral  Antibody Affinity  Antigens, Viral  Betacoronavirus  Binding Sites  Cross Reactions  Crystallography, X-Ray  Epitopes  Models, Molecular  Peptidyl-Dipeptidase A  Protein Conformation  Protein Domains  Protein Interaction Domains and Motifs  Receptors, Virus  SARS Virus  Spike Glycoprotein, Coronavirus  
Quantifying SARS-CoV-2 transmission suggests epidemic control with digital contact tracing 期刊论文
, 2020, 卷号: 368, 期号: 6491
作者:  Ferretti L.;  Wymant C.;  Kendall M.;  Zhao L.;  Nurtay A.;  Abeler-Dörner L.;  Parker M.;  Bonsall D.;  Fraser C.
收藏  |  浏览/下载：32/0  |  提交时间：2020/07/28
disease control  epidemic  memory  parasite transmission  viral disease  Article  asymptomatic disease  China  contact examination  coronavirus disease 2019  disease control  disease transmission  health care system  human  incubation time  mathematical model  mobile application  mortality rate  priority journal  quarantine  rating scale  Severe acute respiratory syndrome coronavirus 2  virus transmission  algorithm  basic reproduction number  Betacoronavirus  contact examination  Coronavirus infection  epidemic  ethics  infection control  mobile application  mobile phone  pandemic  probability  procedures  theoretical model  time factor  virus pneumonia  Coronavirus  SARS coronavirus  Algorithms  Asymptomatic Diseases  Basic Reproduction Number  Betacoronavirus  Cell Phone  China  Contact Tracing  Coronavirus Infections  Epidemics  Humans  Infection Control  Mobile Applications  Models, Theoretical  Pandemics  Pneumonia, Viral  Probability  Quarantine  Time Factors