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Pathway-based predictive approaches for non-animal assessment of acute inhalation toxicity
期刊论文
TOXICOLOGY IN VITRO, 2018, 卷号: 52, 页码: 131-145
作者:
Clippinger, Amy J.
;
Allen, David
;
Behrsing, Holger
;
BeruBe, Kelly A.
;
Bolger, Michael B.
;
Casey, Warren
;
DeLorme, Michael
;
Gaca, Marianna
;
Gehen, Sean C.
;
Glover, Kyle
;
Hayden, Patrick
;
Hinderliter, Paul
;
Hotchkiss, Jon A.
;
Iskandar, Anita
;
Keyser, Brian
;
Luettich, Karsta
;
Ma-Hock, Lan
;
Maione, Anna G.
;
Makena, Patrudu
;
Melbourne, Jodie
;
Milchak, Lawrence
;
Ng, Sheung P.
;
Paini, Alicia
;
Page, Kathryn
;
Patlewicz, Grace
;
Prieto, Pilar
;
Raabe, Hans
;
Reinke, Emily N.
;
Roper, Clive
;
Rose, Jane
;
Sharma, Monita
;
Spoo, Wayne
;
Thorne, Peter S.
;
Wilson, Daniel M.
;
Jarabek, Annie M.
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2019/05/04
Evaluation and Optimization of Pharmacokinetic Models for in Vitro to in Vivo Extrapolation of Estrogenic Activity for Environmental Chemicals
期刊论文
ENVIRONMENTAL HEALTH PERSPECTIVES, 2018, 卷号: 126, 期号: 9
作者:
Casey, Warren M.
;
Chang, Xiaoqing
;
Allen, David G.
;
Ceger, Patricia C.
;
Choksi, Neepa Y.
;
Hsieh, Jui-Hua
;
Wetmore, Barbara A.
;
Ferguson, Stephen S.
;
DeVito, Michael J.
;
Sprankle, Catherine S.
;
Kleinstreuer, Nicole C.
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2019/05/04
Status of acute systemic toxicity testing requirements and data uses by US regulatory agencies
期刊论文
REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2018, 卷号: 94, 页码: 183-196
作者:
Strickland, Judy
;
Clippinger, Amy J.
;
Brown, Jeffrey
;
Allen, David
;
Jacobs, Abigail
;
Matheson, Joanna
;
Lowit, Anna
;
Reinke, Emily N.
;
Johnson, Mark S.
;
Quinn, Michael J., Jr.
;
Mattie, David
;
Fitzpatrick, Suzanne C.
;
Ahir, Surender
;
Kleinstreuer, Nicole
;
Casey, Warren
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/05/04
In vitro to in vivo extrapolation for high throughput prioritization and decision making
期刊论文
TOXICOLOGY IN VITRO, 2018, 卷号: 47, 页码: 213-227
作者:
Bell, Shannon M.
;
Chang, Xiaoqing
;
Wambaugh, John F.
;
Allen, David G.
;
Bartels, Mike
;
Brouwer, Kim L. R.
;
Casey, Warren M.
;
Choksi, Neepa
;
Ferguson, Stephen S.
;
Fraczkiewicz, Grazyna
;
Jarabek, Annie M.
;
Ke, Alice
;
Lumen, Annie
;
Lynn, Scott G.
;
Paini, Alicia
;
Price, Paul S.
;
Ring, Caroline
;
Simon, Ted W.
;
Sipes, Nisha S.
;
Sprankle, Catherine S.
;
Strickland, Judy
;
Troutman, John
;
Wetmore, Barbara A.
;
Kleinstreuer, Nicole C.
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2019/05/04
The US Federal Tox21 Program: A Strategic and Operational Plan for Continued Leadership
期刊论文
ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION, 2018, 卷号: 35, 期号: 2, 页码: 163-168
作者:
Thomas, Russell S.
;
Paules, Richard S.
;
Simeonov, Anton
;
Fitzpatrick, Suzanne C.
;
Crofton, Kevin M.
;
Casey, Warren M.
;
Mendrick, Donna L.
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/05/04
Application of Adverse Outcome Pathways to US EPA's Endocrine Disruptor Screening Program
期刊论文
ENVIRONMENTAL HEALTH PERSPECTIVES, 2017, 卷号: 125, 期号: 9
作者:
Browne, Patience
;
Noyes, Pamela D.
;
Casey, Warren M.
;
Dix, David J.
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/05/04
Prediction of skin sensitization potency using machine learning approaches
期刊论文
JOURNAL OF APPLIED TOXICOLOGY, 2017, 卷号: 37, 期号: 7, 页码: 792-805
作者:
Zang, Qingda
;
Paris, Michael
;
Lehmann, David M.
;
Bell, Shannon
;
Kleinstreuer, Nicole
;
Allen, David
;
Matheson, Joanna
;
Jacobs, Abigail
;
Casey, Warren
;
Strickland, Judy
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/05/04
Identifying environmental chemicals as agonists of the androgen receptor by using a quantitative high-throughput screening platform
期刊论文
TOXICOLOGY, 2017, 卷号: 385, 页码: 48-58
作者:
Lynch, Caitlin
;
Sakamuru, Srilatha
;
Huang, Ruili
;
Stavreva, Diana A.
;
Varticovski, Lyuba
;
Hager, Gordon L.
;
Judson, Richard S.
;
Houck, Keith A.
;
Kleinstreuer, Nicole C.
;
Casey, Warren
;
Paules, Richard S.
;
Simeonov, Anton
;
Xia, Menghang
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2019/05/04
Alternative approaches for identifying acute systemic toxicity: Moving from research to regulatory testing
期刊论文
TOXICOLOGY IN VITRO, 2017, 卷号: 41, 页码: 245-259
作者:
Hamm, Jon
;
Sullivan, Kristie
;
Clippinger, Amy J.
;
Strickland, Judy
;
Bell, Shannon
;
Bhhatarai, Barun
;
Blaauboer, Bas
;
Casey, Warren
;
Dorman, David
;
Forsby, Anna
;
Garcia-Reyero, Natalia
;
Gehen, Sean
;
Graepel, Rabea
;
Hotchkiss, Jon
;
Lowit, Anna
;
Matheson, Joanna
;
Reaves, Elissa
;
Scarano, Louis
;
Sprankle, Catherine
;
Tunkel, Jay
;
Wilson, Dan
;
Xia, Menghang
;
Zhu, Hao
;
Allen, David
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2019/05/04
Development and Validation of a Computational Model for Androgen Receptor Activity
期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2017, 卷号: 30, 期号: 4, 页码: 946-964
作者:
Kleinstreuer, Nicole C.
;
Ceger, Patricia
;
Watt, Eric D.
;
Martin, Matthew
;
Houck, Keith
;
Browne, Patience
;
Thomas, Russell S.
;
Casey, Warren M.
;
Dix, David J.
;
Allen, David
;
Sakamuru, Srilatha
;
Xia, Menghang
;
Huang, Ruili
;
Judson, Richard
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/05/04