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Pathway-based predictive approaches for non-animal assessment of acute inhalation toxicity 期刊论文
TOXICOLOGY IN VITRO, 2018, 卷号: 52, 页码: 131-145
作者:  Clippinger, Amy J.;  Allen, David;  Behrsing, Holger;  BeruBe, Kelly A.;  Bolger, Michael B.;  Casey, Warren;  DeLorme, Michael;  Gaca, Marianna;  Gehen, Sean C.;  Glover, Kyle;  Hayden, Patrick;  Hinderliter, Paul;  Hotchkiss, Jon A.;  Iskandar, Anita;  Keyser, Brian;  Luettich, Karsta;  Ma-Hock, Lan;  Maione, Anna G.;  Makena, Patrudu;  Melbourne, Jodie;  Milchak, Lawrence;  Ng, Sheung P.;  Paini, Alicia;  Page, Kathryn;  Patlewicz, Grace;  Prieto, Pilar;  Raabe, Hans;  Reinke, Emily N.;  Roper, Clive;  Rose, Jane;  Sharma, Monita;  Spoo, Wayne;  Thorne, Peter S.;  Wilson, Daniel M.;  Jarabek, Annie M.
收藏  |  浏览/下载:46/0  |  提交时间:2019/05/04
Representing the Process of Inflammation as Key Events in Adverse Outcome Pathways 期刊论文
TOXICOLOGICAL SCIENCES, 2018, 卷号: 163, 期号: 2, 页码: 346-352
作者:  Villeneuve, Daniel L.;  Landesmann, Brigitte;  Allavena, Paola;  Ashley, Noah;  Bal-Price, Anna;  Corsini, Emanuela;  Halappanavar, Sabina;  Hussell, Tracy;  Laskin, Debra;  Lawrence, Toby;  Nikolic-Paterson, David;  Pallardy, Marc;  Paini, Alicia;  Pieters, Raymond;  Roth, Robert;  Tschudi-Monnet, Florianne
收藏  |  浏览/下载:19/0  |  提交时间:2019/05/04
In vitro to in vivo extrapolation for high throughput prioritization and decision making 期刊论文
TOXICOLOGY IN VITRO, 2018, 卷号: 47, 页码: 213-227
作者:  Bell, Shannon M.;  Chang, Xiaoqing;  Wambaugh, John F.;  Allen, David G.;  Bartels, Mike;  Brouwer, Kim L. R.;  Casey, Warren M.;  Choksi, Neepa;  Ferguson, Stephen S.;  Fraczkiewicz, Grazyna;  Jarabek, Annie M.;  Ke, Alice;  Lumen, Annie;  Lynn, Scott G.;  Paini, Alicia;  Price, Paul S.;  Ring, Caroline;  Simon, Ted W.;  Sipes, Nisha S.;  Sprankle, Catherine S.;  Strickland, Judy;  Troutman, John;  Wetmore, Barbara A.;  Kleinstreuer, Nicole C.
收藏  |  浏览/下载:40/0  |  提交时间:2019/05/04
Investigating the state of physiologically based kinetic modelling practices and challenges associated with gaining regulatory acceptance of model applications 期刊论文
REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2017, 卷号: 90, 页码: 104-115
作者:  Paini, Alicia;  Leonard, Jeremy A.;  Kliment, Tomas;  Tan, Yu-Mei;  Worth, Andrew
收藏  |  浏览/下载:50/0  |  提交时间:2019/05/04
How Adverse Outcome Pathways Can Aid the Development and Use of Computational Prediction Models for Regulatory Toxicology 期刊论文
TOXICOLOGICAL SCIENCES, 2017, 卷号: 155, 期号: 2, 页码: 326-336
作者:  Wittwehr, Clemens;  Aladjov, Hristo;  Ankley, Gerald;  Byrne, Hugh J.;  de Knecht, Joop;  Heinzle, Elmar;  Klambauer, Guenter;  Landesmann, Brigitte;  Luijten, Mirjam;  MacKay, Cameron;  Maxwell, Gavin;  Meek, M. E. (Bette);  Paini, Alicia;  Perkins, Edward;  Sobanski, Tomasz;  Villeneuve, Dan;  Waters, Katrina M.;  Whelan, Maurice
收藏  |  浏览/下载:33/0  |  提交时间:2019/05/04
Putative adverse outcome pathways relevant to neurotoxicity 期刊论文
CRITICAL REVIEWS IN TOXICOLOGY, 2015, 卷号: 45, 期号: 1, 页码: 83-91
作者:  Bal-Price, Anna;  Crofton, Kevin M.;  Sachana, Magdalini;  Shafer, Timothy J.;  Behl, Mamta;  Forsby, Anna;  Hargreaves, Alan;  Landesmann, Brigitte;  Lein, Pamela J.;  Louisse, Jochem;  Monnet-Tschudi, Florianne;  Paini, Alicia;  Rolaki, Alexandra;  Schrattenholz, Andre;  Sunol, Cristina;  van Thriel, Christoph;  Whelan, Maurice;  Fritsche, Ellen
收藏  |  浏览/下载:25/0  |  提交时间:2019/05/04