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Glucocorticoid receptor condensates link DNA-dependent receptor dimerization and transcriptional transactivation 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 30
作者:  Frank F.;  Liu X.;  Ortlund E.A.
收藏  |  浏览/下载：23/0  |  提交时间：2022/02/22
Reconstitution of an intact clock reveals mechanisms of circadian timekeeping 期刊论文
Science, 2021, 卷号: 374, 期号: 6564
作者:  Chavan A.G.;  Swan J.A.;  Heisler J.;  Sancar C.;  Ernst D.C.;  Fang M.;  Palacios J.G.;  Spangler R.K.;  Bagshaw C.R.;  Tripathi S.;  Crosby P.;  Golden S.S.;  Partch C.L.;  LiWang A.
收藏  |  浏览/下载：29/0  |  提交时间：2022/01/14
lncRNA SLERT controls phase separation of FC/DFCs to facilitate Pol I transcription 期刊论文
Science, 2021, 卷号: 373, 期号: 6554
作者:  Wu M.;  Xu G.;  Han C.;  Luan P.-F.;  Xing Y.-H.;  Nan F.;  Yang L.-Z.;  Huang Y.;  Yang Z.-H.;  Shan L.;  Yang L.;  Liu J.;  Chen L.-L.
收藏  |  浏览/下载：30/0  |  提交时间：2022/01/14
Mirror-image antiparallel β-sheets organize water molecules into superstructures of opposite chirality 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 117, 期号: 52
作者:  Perets E.A.;  Konstantinovsky D.;  Fu L.;  Chen J.;  Wang H.-F.;  Hammes-Schiffer S.;  Yan E.C.Y.
收藏  |  浏览/下载：23/0  |  提交时间：2021/05/24
Locking mixed-lineage kinase domain-like protein in its auto-inhibited state prevents necroptosis 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 117, 期号: 52
作者:  Rübbelke M.;  Fiegen D.;  Bauer M.;  Binder F.;  Hamilton J.;  King J.;  Thamm S.;  Nar H.;  Zeeb M.
收藏  |  浏览/下载：37/0  |  提交时间：2021/05/24
Multiple domain interfaces mediate SARM1 autoinhibition 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 4
作者:  Shen C.;  Vohra M.;  Zhang P.;  Mao X.;  Figley M.D.;  Zhu J.;  Sasaki Y.;  Wu H.;  DiAntonio A.;  Milbrandt J.
收藏  |  浏览/下载：31/0  |  提交时间：2021/05/24
The histone H3-H4 tetramer is a copper reductase enzyme 期刊论文
, 2020, 卷号: 369, 期号: 6499
作者:  Attar N.;  Campos O.A.;  Vogelauer M.;  Cheng C.;  Xue Y.;  Schmollinger S.;  Salwinski L.;  Mallipeddi N.V.;  Boone B.A.;  Yen L.;  Yang S.;  Zikovich S.;  Dardine J.;  Carey M.F.;  Merchant S.S.;  Kurdistani S.K.
收藏  |  浏览/下载：16/0  |  提交时间：2020/07/28
copper  copper oxidase  copper zinc superoxide dismutase  histone  MAC1 protein, S cerevisiae  nuclear protein  oxidoreductase  recombinant protein  Saccharomyces cerevisiae protein  transcription factor  animal  biocatalysis  chemistry  enzyme active site  enzymology  gain of function mutation  genetics  metabolism  mitochondrion  protein multimerization  Saccharomyces cerevisiae  Xenopus laevis  Animals  Biocatalysis  Catalytic Domain  Copper  Gain of Function Mutation  Histones  Mitochondria  Nuclear Proteins  Oxidoreductases  Protein Multimerization  Recombinant Proteins  Saccharomyces cerevisiae  Saccharomyces cerevisiae Proteins  Superoxide Dismutase-1  Transcription Factors  Xenopus laevis  
Structural evidence for a dynamic metallocofactor during N2 reduction by Mo-nitrogenase 期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:  Kang W.;  Lee C.C.;  Jasniewski A.J.;  Ribbe M.W.;  Hu Y.
收藏  |  浏览/下载：41/0  |  提交时间：2020/07/28
ammonia  catalysis  crystal structure  enzyme activity  ligand  physiological response  sulfur  ligand  molybdenum iron protein  nitrogen  sulfur  Azotobacter vinelandii  biocatalysis  chemistry  enzymology  oxidation reduction reaction  protein multimerization  X ray crystallography  Azotobacter vinelandii  Biocatalysis  Crystallography, X-Ray  Ligands  Molybdoferredoxin  Nitrogen  Oxidation-Reduction  Protein Multimerization  Sulfur  
Determination of the melanocortin-4 receptor structure identifies Ca2+ as a cofactor for ligand binding 期刊论文
, 2020, 卷号: 368, 期号: 6489
作者:  Yu J.;  Gimenez L.E.;  Hernandez C.C.;  Wu Y.;  Wein A.H.;  Han G.W.;  McClary K.;  Mittal S.R.;  Burdsall K.;  Stauch B.;  Wu L.;  Stevens S.N.;  Peisley A.;  Williams S.Y.;  Chen V.;  Millhauser G.L.;  Zhao S.;  Cone R.D.;  Stevens R.C.
收藏  |  浏览/下载：30/0  |  提交时间：2020/07/28
alpha intermedin  calcium ion  cyclic AMP  G protein coupled receptor  heterotrimeric guanine nucleotide binding protein  inwardly rectifying potassium channel  inwardly rectifying potassium channel subunit Kir7.1  melanocortin 4 receptor  n acetyl alpha intermedin[4-10]cyclo[4 norleucine 5 aspartic acid 7 [3 (2 naphthyl)alanine] 10 lysinamide]  unclassified drug  calcium  G protein coupled receptor  intermedin  inwardly rectifying potassium channel  Kir7.1 channel  ligand  melanocortin 4 receptor  n acetyl alpha intermedin[4-10]cyclo[4 norleucine 5 aspartic acid 7 [3 (2 naphthyl)alanine] 10 lysinamide]  protein binding  calcium  chemical binding  homeostasis  hormone  ligand  obesity  peptide  protein  Article  binding affinity  complex formation  crystallization  drug structure  extracellular calcium  human  ligand binding  priority journal  protein structure  receptor blocking  signal transduction  chemistry  genetics  mutation  protein multimerization  protein secondary structure  X ray crystallography  Calcium  Crystallography, X-Ray  Cyclic AMP  Humans  Ligands  Melanocyte-Stimulating Hormones  Mutation  Potassium Channels, Inwardly Rectifying  Protein Binding  Protein Multimerization  Protein Structure, Secondary  Receptor, Melanocortin, Type 4  Receptors, G-Protein-Coupled  Signal Transduction  
Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2 期刊论文
, 2020, 卷号: 367, 期号: 6485
作者:  Yan R.;  Zhang Y.;  Li Y.;  Xia L.;  Guo Y.;  Zhou Q.
收藏  |  浏览/下载：17/0  |  提交时间：2020/07/28
angiotensin converting enzyme 2  coronavirus spike glycoprotein  heterodimer  homodimer  amino acid transporter  angiotensin converting enzyme 2  dipeptidyl carboxypeptidase  protein binding  SLC6A19 protein, human  spike protein, SARS-CoV-2  virus receptor  enzyme  gene  gene expression  protein  ultrastructure  virus  Article  binding site  complex formation  controlled study  coronavirus disease 2019  cryoelectron microscopy  dimerization  embryo  enzyme structure  human  human cell  nonhuman  priority journal  protein domain  SARS-related coronavirus  Severe acute respiratory syndrome coronavirus 2  amino acid sequence  Betacoronavirus  Coronavirus infection  molecular model  pandemic  protein multimerization  SARS coronavirus  sequence alignment  ultrastructure  virus pneumonia  Coronavirus  SARS coronavirus  Amino Acid Sequence  Amino Acid Transport Systems, Neutral  Betacoronavirus  Coronavirus Infections  Cryoelectron Microscopy  Humans  Models, Molecular  Pandemics  Peptidyl-Dipeptidase A  Pneumonia, Viral  Protein Binding  Protein Domains  Protein Multimerization  Receptors, Virus  SARS Virus  Sequence Alignment  Spike Glycoprotein, Coronavirus