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The anti-liver fibrosis effect of Tibetan medicine (Qiwei Tiexie capsule) is related to the inhibition of NLRP3 inflammasome activation in vivo and in vitro 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2024, 卷号: 319
作者:  Wang, Shanshan;  Ye, Fei;  Ren, Qingjia;  Sun, Shengnan;  Xia, Weina;  Wang, Zhuwei;  Guo, Haolin;  Li, Han;  Zhang, Shujing;  Lowe, Scott;  Chen, Meng;  Du, Qinghong;  Li, Weihong
收藏  |  浏览/下载：14/0  |  提交时间：2024/03/01
Tibetan medicine  Qiwei tiexie capsule  Liver fibrosis  Inflammation  NLRP3 inflammasome  
Integrating UPLC-Q-Exactive Orbitrap/MS, network pharmacology and experimental validation to reveal the potential mechanism of Tibetan medicine Rhodiola granules in improving myocardial ischemia-reperfusion injury 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 314
作者:  Xing, Nan;  Qin, Jing;  Ren, Dongsheng;  Du, Qinyun;  Li, Yuying;  Mi, Jiao;  Zhang, Fengming;  Ai, Li;  Zhang, Sanyin;  Zhang, Yi;  Wang, Shaohui
收藏  |  浏览/下载：7/0  |  提交时间：2024/03/01
UPLC-Q-exactive orbitrap  MS  Network pharmacology  Rhodiola granules  Myocardial ischemia-reperfusion injury  Experimental validation  
Systematic analysis of differential rhythmic liver gene expression mediated by the circadian clock and feeding rhythms 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 3
作者:  Weger B.D.;  Gobet C.;  David F.P.A.;  Atger F.;  Martin E.;  Phillips N.E.;  Charpagne A.;  Weger M.;  Naef F.;  Gachon F.
收藏  |  浏览/下载：14/0  |  提交时间：2021/05/24
Protective Effect of Two Alkaloids from Hippophae rhamnoides Linn. against Doxorubicin-Induced Toxicity in H9c2 Cardiomyoblasts 期刊论文
MOLECULES, 2021, 卷号: 26, 期号: 7
作者:  Zhou, Wenna;  Ouyang, Jian;  Hu, Na;  Li, Gang;  Wang, Honglun
收藏  |  浏览/下载：24/0  |  提交时间：2022/04/28
Profiles of messenger RNAs and MicroRNAs in hypoxia-induced hepatic stellate cells 期刊论文
ANNALS OF TRANSLATIONAL MEDICINE, 2021, 卷号: 9, 期号: 18
作者:  Zhang, Liting;  Gao, Jing;  Zhou, Dan;  Wang, Xiaojun;  Li, Junfeng;  Wang, Juan;  Chen, Hong;  Xie, Xiaodong;  Chen, Tuo
收藏  |  浏览/下载：30/0  |  提交时间：2022/04/28
INDUCIBLE FACTORS  ACTIVATION  PATHWAY  EXPRESSION  
N-salicyloyl tryptamine derivatives as potential therapeutic agents for Alzheimer's disease with neuroprotective effects 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 115
作者:  Bai, Yinliang;  Liu, Dan;  Zhang, Honghua;  Wang, Yuying;  Wang, Degui;  Cai, Hongbin;  Wen, Huaixiu;  Yuan, Guoqiang;  An, Hui;  Wang, Yali;  Shi, Tao;  Wang, Zhen
收藏  |  浏览/下载：33/0  |  提交时间：2022/04/28
CELL-DEATH  INFLAMMASOME  PYROPTOSIS  NEUROINFLAMMATION  MICROGLIA  MECHANISM  APOPTOSIS  
Discovery of a caspase cleavage motif antibody reveals insights into noncanonical inflammasome function 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 12
作者:  Davies C.W.;  Stowe I.;  Phung Q.T.;  Ho H.;  Bakalarski C.E.;  Gupta A.;  Zhang Y.;  Lill J.R.;  Payandeh J.;  Kayagaki N.;  Koerber J.T.
收藏  |  浏览/下载：33/0  |  提交时间：2021/05/24
An AMPK–caspase-6 axis controls liver damage in nonalcoholic steatohepatitis 期刊论文
, 2020, 卷号: 367, 期号: 6478
作者:  Zhao P.;  Sun X.;  Chaggan C.;  Liao Z.;  Wong K.I.;  He F.;  Singh S.;  Loomba R.;  Karin M.;  Witztum J.L.;  Saltiel A.R.
收藏  |  浏览/下载：35/0  |  提交时间：2020/07/28
6,7 dihydro 4 hydroxy 3 (2' hydroxy 1,1' biphenyl 4 yl) 6 oxothieno[2,3 b]pyridine 5 carbonitrile  adenosine phosphate  caspase 3  caspase 6  caspase 7  cytochrome c  hydroxymethylglutaryl coenzyme A reductase kinase  matrix metalloproteinase  apoptosis  cytochrome  enzyme  enzyme activity  inhibition  protein  rodent  AMPK signaling  animal experiment  animal model  animal tissue  apoptosis  Article  C57BL 6 mouse  cell death  controlled study  drug mechanism  enzyme activation  enzyme activity  enzyme inhibition  enzyme phosphorylation  enzyme repression  gene knockout  human  human cell  human tissue  liver cell  liver fibrosis  liver injury  male  mouse  nonalcoholic steatohepatitis  nonhuman  priority journal  protein cleavage  protein secretion  
Influence of salinity on spermatogenesis in adult Nile tilapia (Oreochromis niloticus) testis 期刊论文
THERIOGENOLOGY, 2019, 卷号: 131, 页码: 1-8
作者:  Cruz Vieira, Augusto Bicalho;  Weber, Andre Alberto;  Ribeiro, Yves Moreira;  Luz, Ronald Kennedy;  Bazzoli, Nilo;  Rizzo, Elizete
收藏  |  浏览/下载：18/0  |  提交时间：2019/11/07
Elevated temperature attenuates ovarian functions and induces apoptosis and oxidative stress in the American oyster, Crassostrea virginica: potential mechanisms and signaling pathways 期刊论文
CELL STRESS & CHAPERONES, 2019, 卷号: 24, 期号: 5, 页码: 957-967
作者:  Nash, Sarah;  Johnstone, Jackson;  Rahman, Md Saydur
收藏  |  浏览/下载：16/0  |  提交时间：2019/11/07