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The anti-liver fibrosis effect of Tibetan medicine (Qiwei Tiexie capsule) is related to the inhibition of NLRP3 inflammasome activation in vivo and in vitro 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2024, 卷号: 319
作者:  Wang, Shanshan;  Ye, Fei;  Ren, Qingjia;  Sun, Shengnan;  Xia, Weina;  Wang, Zhuwei;  Guo, Haolin;  Li, Han;  Zhang, Shujing;  Lowe, Scott;  Chen, Meng;  Du, Qinghong;  Li, Weihong
收藏  |  浏览/下载：10/0  |  提交时间：2024/03/01
Tibetan medicine  Qiwei tiexie capsule  Liver fibrosis  Inflammation  NLRP3 inflammasome  
Loss of hepatic miR-33 improves metabolic homeostasis and liver function without altering body weight or atherosclerosis 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 5
作者:  Price N.L.;  Zhang X.;  Fernández-Tussy P.;  Singh A.K.;  Burnap S.A.;  Rotllan N.;  Goedeke L.;  Sun J.;  Canfrán-Duque A.;  Aryal B.;  Mayr M.;  Suárez Y.;  Fernández-Hernando C.
收藏  |  浏览/下载：42/0  |  提交时间：2021/05/24
Scaling concepts in 'omics: Nuclear lamin-B scales with tumor growth and often predicts poor prognosis, unlike fibrosis 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 48
作者:  Vashisth M.;  Cho S.;  Irianto J.;  Xia Y.;  Wang M.;  Hayes B.;  Wieland D.;  Wells R.;  Jafarpour F.;  Liu A.;  Discher D.E.
收藏  |  浏览/下载：29/0  |  提交时间：2022/02/22
Profiles of messenger RNAs and MicroRNAs in hypoxia-induced hepatic stellate cells 期刊论文
ANNALS OF TRANSLATIONAL MEDICINE, 2021, 卷号: 9, 期号: 18
作者:  Zhang, Liting;  Gao, Jing;  Zhou, Dan;  Wang, Xiaojun;  Li, Junfeng;  Wang, Juan;  Chen, Hong;  Xie, Xiaodong;  Chen, Tuo
收藏  |  浏览/下载：26/0  |  提交时间：2022/04/28
INDUCIBLE FACTORS  ACTIVATION  PATHWAY  EXPRESSION  
TLR2 inhibition ameliorates the amplification effect of LPS on lipid accumulation and lipotoxicity in hepatic cells 期刊论文
ANNALS OF TRANSLATIONAL MEDICINE, 2021, 卷号: 9, 期号: 18
作者:  Zhang, Liting;  Xie, Zehui;  Yu, Hongmiao;  Du, Haoxuan;  Wang, Xuqiao;  Cai, Jiazheng;  Qiu, Yingfei;  Chen, Rui;  Jiang, Xiaofeng;  Liu, Zelin;  Li, Yi;  Chen, Tuo
收藏  |  浏览/下载：32/0  |  提交时间：2022/04/28
FATTY LIVER-DISEASE  NONALCOHOLIC STEATOHEPATITIS  ADVANCED FIBROSIS  LIPOPOLYSACCHARIDE  RECEPTORS  AXIS  ACID  
Chitinase 3-like 1 is a profibrogenic factor overexpressed in the aging liver and in patients with liver cirrhosis 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 17
作者:  Nishimura N.;  De Battista D.;  McGivern D.R.;  Engle R.E.;  Tice A.;  Fares-Gusmao R.;  Kabat J.;  Pomerenke A.;  Nguyen H.;  Sato S.;  Bock K.W.;  Moore I.N.;  Kleiner D.E.;  Zamboni F.;  Alter H.J.;  Govindarajan S.;  Farci P.
收藏  |  浏览/下载：30/0  |  提交时间：2021/05/24
Oral administration of PEGylated TLR7 ligand ameliorates alcohol-associated liver disease via the induction of IL-22 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 1
作者:  Wang Q.;  Kim S.Y.;  Matsushita H.;  Wang Z.;  Pandyarajan V.;  Matsuda M.;  Ohashi K.;  Tsuchiya T.;  Roh Y.S.;  Kiani C.;  Zhao Y.;  Chan M.;  Devkota S.;  Lu S.C.;  Hayashi T.;  Carson D.A.;  Seki E.
收藏  |  浏览/下载：37/0  |  提交时间：2021/05/24
Up-regulation of miR-34b/c by JNK and FOXO3 protects from liver fibrosis 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 10
作者:  Piccolo P.;  Ferriero R.;  Barbato A.;  Attanasio S.;  Monti M.;  Perna C.;  Borel F.;  Annunziata P.;  Carissimo A.;  De Cegli R.;  Quagliata L.;  Terracciano L.M.;  Housset C.;  Teckman J.H.;  Mueller C.;  Brunetti-Pierri N.
收藏  |  浏览/下载：18/0  |  提交时间：2021/05/24
An AMPK–caspase-6 axis controls liver damage in nonalcoholic steatohepatitis 期刊论文
, 2020, 卷号: 367, 期号: 6478
作者:  Zhao P.;  Sun X.;  Chaggan C.;  Liao Z.;  Wong K.I.;  He F.;  Singh S.;  Loomba R.;  Karin M.;  Witztum J.L.;  Saltiel A.R.
收藏  |  浏览/下载：32/0  |  提交时间：2020/07/28
6,7 dihydro 4 hydroxy 3 (2' hydroxy 1,1' biphenyl 4 yl) 6 oxothieno[2,3 b]pyridine 5 carbonitrile  adenosine phosphate  caspase 3  caspase 6  caspase 7  cytochrome c  hydroxymethylglutaryl coenzyme A reductase kinase  matrix metalloproteinase  apoptosis  cytochrome  enzyme  enzyme activity  inhibition  protein  rodent  AMPK signaling  animal experiment  animal model  animal tissue  apoptosis  Article  C57BL 6 mouse  cell death  controlled study  drug mechanism  enzyme activation  enzyme activity  enzyme inhibition  enzyme phosphorylation  enzyme repression  gene knockout  human  human cell  human tissue  liver cell  liver fibrosis  liver injury  male  mouse  nonalcoholic steatohepatitis  nonhuman  priority journal  protein cleavage  protein secretion  
Triclosan leads to dysregulation of the metabolic regulator FGF21 exacerbating high fat diet-induced nonalcoholic fatty liver disease 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2020, 卷号: 117, 期号: 49
作者:  Yueh M.-F.;  He F.;  Chen C.;  Vu C.;  Tripathi A.;  Knight R.;  Karin M.;  Chen S.;  Tukey R.H.
收藏  |  浏览/下载：33/0  |  提交时间：2021/01/06