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| Climate Change 2022: Mitigation of Climate Change 科技报告 , 2022 作者: Jim Skea JPEG(8Kb)  |  收藏  |  浏览/下载:134/33  |  提交时间:2022/04/06 |
| New proteins 'out of nothing' 科技资讯 2021 收藏  |  浏览/下载:19/0  |  提交时间:2021/03/13 |
| Acceleration of catalysis in dihydrofolate reductase by transient, site-specific photothermal excitation 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 4 作者: Kozlowski R.; Zhao J.; Brian Dyer R. 收藏  |  浏览/下载:18/0  |  提交时间:2021/05/24 |
| SARS-CoV-2 escape from a highly neutralizing COVID-19 convalescent plasma 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 36 作者: Andreano E.; Piccini G.; Licastro D.; Casalino L.; Johnson N.V.; Paciello I.; Monego S.D.; Pantano E.; Manganaro N.; Manenti A.; Manna R.; Casa E.; Hyseni I.; Benincasa L.; Montomoli E.; Amaro R.E.; McLellan J.S.; Rappuoli R. 收藏  |  浏览/下载:37/0  |  提交时间:2021/11/25 |
| Structures of the human Mediator and Mediator-bound preinitiation complex 期刊论文 Science, 2021, 卷号: 372, 期号: 6546 作者: Chen X.; Yin X.; Li J.; Wu Z.; Qi Y.; Wang X.; Liu W.; Xu Y. 收藏  |  浏览/下载:1/0  |  提交时间:2022/01/14 |
| The myosin II coiled-coil domain atomic structure in its native environment 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 14 作者: Rahmani H.; Ma W.; Hu Z.; Daneshparvar N.; Taylor D.W.; McCammon J.A.; Irving T.C.; Edwards R.J.; Taylor K.A. 收藏  |  浏览/下载:23/0  |  提交时间:2021/05/24 |
| Cryoelectron microscopy structure and mechanism of the membrane-associated electron-bifurcating flavoprotein Fix/EtfABCX 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 2 作者: Feng X.; Schut G.J.; Lipscomb G.L.; Li H.; Adams M.W.W. 收藏  |  浏览/下载:44/0  |  提交时间:2021/05/24 |
| Structural basis of Gs and Gi recognition by the human glucagon receptor 期刊论文 , 2020, 卷号: 367, 期号: 6484 作者: Qiao A.; Han S.; Li X.; Li Z.; Zhao P.; Dai A.; Chang R.; Tai L.; Tan Q.; Chu X.; Ma L.; Thorsen T.S.; Reedtz-Runge S.; Yang D.; Wang M.-W.; Sexton P.M.; Wootten D.; Sun F.; Zhao Q.; Wu B. 收藏  |  浏览/下载:32/0  |  提交时间:2020/07/28 cyclic AMP glucagon glucagon receptor inhibitory guanine nucleotide binding protein stimulatory guanine nucleotide binding protein glucagon receptor inhibitory guanine nucleotide binding protein protein binding stimulatory guanine nucleotide binding protein chemical binding enzyme activity gene expression mutagenicity protein alpha helix Article binding affinity carboxy terminal sequence conformational transition cryoelectron microscopy human molecular recognition mutagenesis priority journal protein binding protein function protein protein interaction protein structure signal transduction binding site chemistry metabolism molecular model protein conformation ultrastructure Binding Sites Cryoelectron Microscopy Glucagon GTP-Binding Protein alpha Subunits, Gi-Go GTP-Binding Protein alpha Subunits, Gs Humans Models, Molecular Protein Binding Protein Conformation Protein Conformation, alpha-Helical Receptors, Glucagon Signal Transduction |
| Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR 期刊论文 , 2020, 卷号: 367, 期号: 6480 作者: Wingler L.M.; Skiba M.A.; McMahon C.; Staus D.P.; Kleinhenz A.L.W.; Suomivuori C.-M.; Latorraca N.R.; Dror R.O.; Lefkowitz R.J.; Kruse A.C. 收藏  |  浏览/下载:24/0  |  提交时间:2020/07/28 angiotensin 1 receptor beta arrestin G protein coupled receptor biochemistry crystal chemistry crystal structure physiological response protein signaling allosterism alpha helix amino terminal sequence Article binding affinity binding site carboxy terminal sequence conformational transition crystallization hydrogen bond molecular dynamics priority journal protein binding protein conformation protein protein interaction protein stability signal transduction thermostability |
| Structure of nucleosome-bound human BAF complex 期刊论文 , 2020, 卷号: 367, 期号: 6480 作者: He S.; Wu Z.; Tian Y.; Yu Z.; Yu J.; Wang X.; Li J.; Liu B.; Xu Y. 收藏  |  浏览/下载:29/0  |  提交时间:2020/07/28 actin related protein adenosine triphosphatase BRG1 BRM associated factor DNA multiprotein complex protein SWI retinoblastoma binding protein 2 SMARCC protein SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily B member 1 transcription factor transcription factor SNF unclassified drug cancer enzyme activity gene expression hydrolysis mutation protein alpha helix Article carboxy terminal sequence cell interaction cryoelectron microscopy disease association human malignant neoplasm molecular recognition mutation nucleosome priority journal protein function protein hydrolysis protein structure structure analysis Mammalia |