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Climate Change 2022: Mitigation of Climate Change 科技报告
, 2022
作者:  Jim Skea
JPEG(8Kb)  |  收藏  |  浏览/下载:134/33  |  提交时间:2022/04/06
New proteins 'out of nothing' 科技资讯
2021
收藏  |  浏览/下载:19/0  |  提交时间:2021/03/13
Acceleration of catalysis in dihydrofolate reductase by transient, site-specific photothermal excitation 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 4
作者:  Kozlowski R.;  Zhao J.;  Brian Dyer R.
收藏  |  浏览/下载:18/0  |  提交时间:2021/05/24
SARS-CoV-2 escape from a highly neutralizing COVID-19 convalescent plasma 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 36
作者:  Andreano E.;  Piccini G.;  Licastro D.;  Casalino L.;  Johnson N.V.;  Paciello I.;  Monego S.D.;  Pantano E.;  Manganaro N.;  Manenti A.;  Manna R.;  Casa E.;  Hyseni I.;  Benincasa L.;  Montomoli E.;  Amaro R.E.;  McLellan J.S.;  Rappuoli R.
收藏  |  浏览/下载:37/0  |  提交时间:2021/11/25
Structures of the human Mediator and Mediator-bound preinitiation complex 期刊论文
Science, 2021, 卷号: 372, 期号: 6546
作者:  Chen X.;  Yin X.;  Li J.;  Wu Z.;  Qi Y.;  Wang X.;  Liu W.;  Xu Y.
收藏  |  浏览/下载:1/0  |  提交时间:2022/01/14
The myosin II coiled-coil domain atomic structure in its native environment 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 14
作者:  Rahmani H.;  Ma W.;  Hu Z.;  Daneshparvar N.;  Taylor D.W.;  McCammon J.A.;  Irving T.C.;  Edwards R.J.;  Taylor K.A.
收藏  |  浏览/下载:23/0  |  提交时间:2021/05/24
Cryoelectron microscopy structure and mechanism of the membrane-associated electron-bifurcating flavoprotein Fix/EtfABCX 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 2
作者:  Feng X.;  Schut G.J.;  Lipscomb G.L.;  Li H.;  Adams M.W.W.
收藏  |  浏览/下载:44/0  |  提交时间:2021/05/24
Structural basis of Gs and Gi recognition by the human glucagon receptor 期刊论文
, 2020, 卷号: 367, 期号: 6484
作者:  Qiao A.;  Han S.;  Li X.;  Li Z.;  Zhao P.;  Dai A.;  Chang R.;  Tai L.;  Tan Q.;  Chu X.;  Ma L.;  Thorsen T.S.;  Reedtz-Runge S.;  Yang D.;  Wang M.-W.;  Sexton P.M.;  Wootten D.;  Sun F.;  Zhao Q.;  Wu B.
收藏  |  浏览/下载:32/0  |  提交时间:2020/07/28
cyclic AMP  glucagon  glucagon receptor  inhibitory guanine nucleotide binding protein  stimulatory guanine nucleotide binding protein  glucagon receptor  inhibitory guanine nucleotide binding protein  protein binding  stimulatory guanine nucleotide binding protein  chemical binding  enzyme activity  gene expression  mutagenicity  protein  alpha helix  Article  binding affinity  carboxy terminal sequence  conformational transition  cryoelectron microscopy  human  molecular recognition  mutagenesis  priority journal  protein binding  protein function  protein protein interaction  protein structure  signal transduction  binding site  chemistry  metabolism  molecular model  protein conformation  ultrastructure  Binding Sites  Cryoelectron Microscopy  Glucagon  GTP-Binding Protein alpha Subunits, Gi-Go  GTP-Binding Protein alpha Subunits, Gs  Humans  Models, Molecular  Protein Binding  Protein Conformation  Protein Conformation, alpha-Helical  Receptors, Glucagon  Signal Transduction  
Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR 期刊论文
, 2020, 卷号: 367, 期号: 6480
作者:  Wingler L.M.;  Skiba M.A.;  McMahon C.;  Staus D.P.;  Kleinhenz A.L.W.;  Suomivuori C.-M.;  Latorraca N.R.;  Dror R.O.;  Lefkowitz R.J.;  Kruse A.C.
收藏  |  浏览/下载:24/0  |  提交时间:2020/07/28
angiotensin 1 receptor  beta arrestin  G protein coupled receptor  biochemistry  crystal chemistry  crystal structure  physiological response  protein  signaling  allosterism  alpha helix  amino terminal sequence  Article  binding affinity  binding site  carboxy terminal sequence  conformational transition  crystallization  hydrogen bond  molecular dynamics  priority journal  protein binding  protein conformation  protein protein interaction  protein stability  signal transduction  thermostability  
Structure of nucleosome-bound human BAF complex 期刊论文
, 2020, 卷号: 367, 期号: 6480
作者:  He S.;  Wu Z.;  Tian Y.;  Yu Z.;  Yu J.;  Wang X.;  Li J.;  Liu B.;  Xu Y.
收藏  |  浏览/下载:29/0  |  提交时间:2020/07/28
actin related protein  adenosine triphosphatase  BRG1 BRM associated factor  DNA  multiprotein complex  protein SWI  retinoblastoma binding protein 2  SMARCC protein  SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily B member 1  transcription factor  transcription factor SNF  unclassified drug  cancer  enzyme activity  gene expression  hydrolysis  mutation  protein  alpha helix  Article  carboxy terminal sequence  cell interaction  cryoelectron microscopy  disease association  human  malignant neoplasm  molecular recognition  mutation  nucleosome  priority journal  protein function  protein hydrolysis  protein structure  structure analysis  Mammalia