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| Significant cancer rates in California sea lions has major human health implications 科技资讯
2021
  收藏 | 浏览/下载：5/0 | 提交时间：2021/02/03 |
| Kleine-Levin syndrome is associated with birth difficulties and genetic variants in the TRANK1 gene loci 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 12
作者: Ambati A.; Hillary R.; Leu-Semenescu S.; Ollila H.M.; Lin L.; During E.H.; Farber N.; Rico T.J.; Faraco J.; Leary E.; Goldstein-Piekarski A.N.; Huang Y.-S.; Han F.; Sivan Y.; Lecendreux M.; Dodet P.; Honda M.; Gadoth N.; Nevsimalova S.; Pizza F.; Kanbayashi T.; Peraita-Adrados R.; Leschziner G.D.; Hasan R.; Canellas F.; Kume K.; Daniilidou M.; Bourgin P.; Rye D.; Vicario J.L.; Hogl B.; Hong S.C.; Plazzi G.; Mayer G.; Landtblom A.M.; Dauvilliers Y.; Arnulf I.; Mignot E.J.-M.
收藏 | 浏览/下载：37/0 | 提交时间：2021/05/24 |
| Germ-line mutations in WDR77 predispose to familial papillary thyroid cancer 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 31
作者: Zhao Y.; Yu T.; Sun J.; Wang F.; Cheng C.; He S.; Chen L.; Xie D.; Fu L.; Guan X.; Yan A.; Li Y.; Miao G.; Zhu X.
收藏 | 浏览/下载：88/0 | 提交时间：2022/02/22 |
| Preventing type 1 diabetes in childhood 期刊论文
Science, 2021, 卷号: 373, 期号: 6554
作者: Dayan C.M.; Besser R.E.J.; Oram R.A.; Hagopian W.; Vatish M.; Bendor-Samuel O.; Snape M.D.; Todd J.A.
收藏 | 浏览/下载：20/0 | 提交时间：2022/01/14 |
| Heterozygous germline BLM mutations increase susceptibility to asbestos and mesothelioma 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 117, 期号: 52
作者: Bononi A.; Goto K.; Ak G.; Yoshikawa Y.; Emi M.; Pastorino S.; Carparelli L.; Ferro A.; Nasu M.; Kim J.-H.; Suarez J.S.; Xu R.; Tanji M.; Takinishi Y.; Minaai M.; Novelli F.; Pagano I.; Gaudino G.; Pass H.I.; Groden J.; Grzymski J.J.; Metintas M.; Akarsu M.; Morrow B.; Hassan R.; Yang H.; Carbone M.
收藏 | 浏览/下载：29/0 | 提交时间：2021/05/24 |
| Goblet cell LRRC26 regulates BK channel activation and protects against colitis in mice 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 3
作者: Gonzalez-Perez V.; Martinez-Espinosa P.L.; Sala-Rabanal M.; Bharadwaj N.; Xia X.-M.; Chen A.C.; Alvarado D.; Gustafsson J.K.; Hu H.; Ciorba M.A.; Lingle C.J.
收藏 | 浏览/下载：23/0 | 提交时间：2021/05/24 |
| A genomic region associated with protection against severe COVID-19 is inherited from Neandertals 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 9
作者: Zeberg H.; Pääbo S.
收藏 | 浏览/下载：18/0 | 提交时间：2021/05/24 |
| National Climate Change Risk Assessment for New Zealand 科技报告
, 2020
作者: [unavailable]
 Adobe PDF(5236Kb) | 收藏 | 浏览/下载：10/1 | 提交时间：2021/11/24 |
| Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants 期刊论文
, 2020, 卷号: 368, 期号: 6488
作者: Walton R.T.; Christie K.A.; Whittaker M.N.; Kleinstiver B.P.
收藏 | 浏览/下载：17/0 | 提交时间：2020/07/28
adenine adenosine CRISPR associated endonuclease Cas9 cytosine guanosine SpG protein SpRY nuclease thymine unclassified drug Cas9 endonuclease Streptococcus pyogenes bacterium enzyme activity genetic engineering genetic variation genome Article CRISPR-CAS9 system DNA sequence enzyme activity gene editing gene targeting genetic variability human mutagenesis nonhuman priority journal protein engineering protein motif protein structure protospacer adjacent motif Streptococcus pyogenes chemistry CRISPR Cas system enzyme specificity gene editing gene targeting genetic predisposition genetics HEK293 cell line procedures protein domain Streptococcus pyogenes CRISPR-Associated Protein 9 CRISPR-Cas Systems Gene Editing Gene Targeting Genetic Predisposition to Disease HEK293 Cells Humans Mutagenesis Protein Domains Substrate Specificity |
| TEAD4 ensures postimplantation development by promoting trophoblast self-renewal: An implication in early human pregnancy loss 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2020, 卷号: 117, 期号: 30
作者: Saha B.; Ganguly A.; Home P.; Bhattacharya B.; Ray S.; Ghosh A.; Karim Rumi M.A.; Marsh C.; French V.A.; Gunewardena S.; Paul S.
收藏 | 浏览/下载：39/0 | 提交时间：2021/01/06 |
