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| Biomaterial scaffold-based local drug delivery systems for cancer immunotherapy 期刊论文 Science Bulletin, 2020, 卷号: 65, 期号: 17 作者: Yang C.; Blum N.T.; Lin J.; Qu J.; Huang P. 收藏  |  浏览/下载:22/0  |  提交时间:2021/09/01 Cancer immunotherapy Combination therapy Controlled drug delivery Hydrogel Local drug delivery system Scaffold |
| CRISPR-engineered T cells in patients with refractory cancer 期刊论文 , 2020, 卷号: 367, 期号: 6481 作者: Stadtmauer E.A.; Fraietta J.A.; Davis M.M.; Cohen A.D.; Weber K.L.; Lancaster E.; Mangan P.A.; Kulikovskaya I.; Gupta M.; Chen F.; Tian L.; Gonzalez V.E.; Xu J.; Jung I.-Y.; Joseph Melenhorst J.; Plesa G.; Shea J.; Matlawski T.; Cervini A.; Gaymon A.L.; Desjardins S.; Lamontagne A.; Salas-Mckee J.; Fesnak A.; Siegel D.L.; Levine B.L.; Jadlowsky J.K.; Young R.M.; Chew A.; Hwang W.-T.; Hexner E.O.; Carreno B.M.; Nobles C.L.; Bushman F.D.; Parker K.R.; Qi Y.; Satpathy A.T.; Chang H.Y.; Zhao Y.; Lacey S.F.; June C.H. 收藏  |  浏览/下载:36/0  |  提交时间:2020/07/28 heterodimer programmed death 1 receptor T lymphocyte receptor alpha chain T lymphocyte receptor beta chain cancer cell gene gene expression genetic engineering immunity protein adult aged Article cancer patient cell engineering chromosome translocation clinical article clustered regularly interspaced short palindromic repeat controlled study CRISPR-CAS9 system feasibility study female gene editing gene expression gene frequency gene locus genetic code human human cell male middle aged myeloma PDCD1 gene phase 1 clinical trial priority journal sarcoma T lymphocyte TRAC gene TRBC gene tumor immunity |
| An RNA vaccine drives expansion and efficacy of claudin-CAR-T cells against solid tumors 期刊论文 , 2020, 卷号: 367, 期号: 6476 作者: Reinhard K.; Rengstl B.; Oehm P.; Michel K.; Billmeier A.; Hayduk N.; Klein O.; Kuna K.; Ouchan Y.; Wöll S.; Christ E.; Weber D.; Suchan M.; Bukur T.; Birtel M.; Jahndel V.; Mroz K.; Hobohm K.; Kranz L.; Diken M.; Kühlcke K.; Türeci Ö.; Sahin U. 收藏  |  浏览/下载:39/0  |  提交时间:2020/07/28 chimeric antigen receptor claudin 6 RNA vaccine antigen cell component protein RNA tumor vaccine animal cell animal experiment animal model animal tissue antigen presenting cell antineoplastic activity Article cell stimulation cell transport chimeric antigen receptor T-cell immunotherapy controlled study drug efficacy human human cell in vivo study mouse nonhuman phenotype priority journal real time polymerase chain reaction solid malignant neoplasm therapy effect vaccination coverage |
| The human tumor microbiome is composed of tumor type-specific intracellular bacteria 期刊论文 , 2020, 卷号: 368, 期号: 6494 作者: Nejman D.; Livyatan I.; Fuks G.; Gavert N.; Zwang Y.; Geller L.T.; Rotter-Maskowitz A.; Weiser R.; Mallel G.; Gigi E.; Meltser A.; Douglas G.M.; Kamer I.; Gopalakrishnan V.; Dadosh T.; Levin-Zaidman S.; Avnet S.; Atlan T.; Cooper Z.A.; Arora R.; Cogdill A.P.; Khan M.A.W.; Ologun G.; Bussi Y.; Weinberger A.; Lotan-Pompan M.; Golani O.; Perry G.; Rokah M.; Bahar-Shany K.; Rozeman E.A.; Blank C.U.; Ronai A.; Shaoul R.; Amit A.; Dorfman T.; Kremer R.; Cohen Z.R.; Harnof S.; Siegal T.; Yehuda-Shnaidman E.; Gal-Yam E.N.; Shapira H.; Baldini N.; Langille M.G.I.; Ben-Nun A.; Kaufman B.; Nissan A.; Golan T.; Dadiani M.; Levanon K.; Bar J.; Yust S.; Barshack I.; Peeper D.S.; Raz D.J.; Segal E.; Wargo J.A.; Sandbank J.; Shental N.; Straussman R. 收藏  |  浏览/下载:31/0  |  提交时间:2020/07/28 bacterium cell microorganism tumor RNA 16S bacterium breast classification colon female genetics human immunotherapy isolation and purification lung macrophage male microbiology microflora neoplasm ovary Bacteria Breast Colon Female Humans Immunotherapy Lung Macrophages Male Microbiota Neoplasms Ovary RNA, Ribosomal, 16S |
| Butyrophilin 2A1 is essential for phosphoantigen reactivity by gd T cells 期刊论文 , 2020, 卷号: 367, 期号: 6478 作者: Rigau M.; Ostrouska S.; Fulford T.S.; Johnson D.N.; Woods K.; Ruan Z.; McWilliam H.E.G.; Hudson C.; Tutuka C.; Wheatley A.K.; Kent S.J.; Villadangos J.A.; Pal B.; Kurts C.; Simmonds J.; Pelzing M.; Nash A.D.; Hammet A.; Verhagen A.M.; Vairo G.; Maraskovsky E.; Panousis C.; Gherardin N.A.; Cebon J.; Godfrey D.I.; Behren A.; Uldrich A.P. 收藏  |  浏览/下载:27/0  |  提交时间:2020/07/28 antigen butyrophilin butyrophilin 2A1 butyrophilin 3A1 phosphoantigen unclassified drug antigen cancer cell immune response protein antigen antibody reaction antigen recognition Article controlled study gamma delta T lymphocyte human human cell immunocompetent cell immunotherapy lymphocyte activation priority journal protein analysis protein binding protein domain protein interaction |