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CFLIPL protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation 期刊论文
, 2020, 卷号: 367, 期号: 6484
作者:  Muendlein H.I.;  Jetton D.;  Connolly W.M.;  Eidell K.P.;  Magri Z.;  Smirnova I.;  Poltorak A.
收藏  |  浏览/下载:37/0  |  提交时间:2020/07/28
FLICE inhibitory protein  interleukin 1beta  lipopolysaccharide  messenger RNA  succinate dehydrogenase (ubiquinone)  Casp1 protein, mouse  caspase 8  Cflar protein, mouse  cryopyrin  FLICE inhibitory protein  IL1B protein, mouse  inflammasome  interleukin 1beta  interleukin 1beta converting enzyme  lipopolysaccharide  succinate dehydrogenase (ubiquinone)  cell  enzyme activity  inhibition  maturation  protein  animal cell  animal experiment  Article  bone marrow derived macrophage  cell death  cell protection  complex formation  controlled study  cytokine release  in vitro study  inflammation  mouse  nonhuman  priority journal  protein analysis  protein degradation  protein function  protein interaction  pyroptosis  animal  gene knockdown  genetics  immunology  macrophage  macrophage activation  metabolism  physiology  Murinae  Animals  CASP8 and FADD-Like Apoptosis Regulating Protein  Caspase 1  Caspase 8  Electron Transport Complex II  Gene Knockdown Techniques  Inflammasomes  Interleukin-1beta  Lipopolysaccharides  Macrophage Activation  Macrophages  Mice  NLR Family, Pyrin Domain-Containing 3 Protein  Pyroptosis  
Lipid-gated monovalent ion fluxes regulate endocytic traffic and support immune surveillance 期刊论文
, 2020, 卷号: 367, 期号: 6475
作者:  Freeman S.A.;  Uderhardt S.;  Saric A.;  Collins R.F.;  Buckley C.M.;  Mylvaganam S.;  Boroumand P.;  Plumb J.;  Germain R.N.;  Ren D.;  Grinstein S.
收藏  |  浏览/下载:25/0  |  提交时间:2020/07/28
cation channel  chemokine receptor CCR2  chloride  colony stimulating factor 1  epidermal growth factor  epidermal growth factor receptor  lipid  sialoadhesin  sodium ion  tetrandrine  two pore channel  unclassified drug  calcium channel  lipid  Mcoln1 protein, mouse  sodium  TPCN1 protein, mouse  TPCN2 protein, mouse  transient receptor potential channel  cation  homeostasis  immune system  protein  recycling  animal experiment  Article  bone marrow derived macrophage  cell vacuole  cell volume  channel gating  chloride transport  concentration (parameter)  controlled study  endocytosis  extracellular fluid  extracellular space  homeostasis  human  human cell  human tissue  immunosurveillance  in vitro study  internalization  ion current  knockout mouse  macropinocytosis  mouse  nonhuman  priority journal  protein stability  RNA interference  sodium transport  tonoplast  animal  cell organelle  endosome  genetics  immunology  ion transport  macrophage  metabolism  osmosis  physiology  pinocytosis  Animals  Calcium Channels  Endosomes  Immunologic Surveillance  Ion Transport  Lipids  Macrophages  Mice  Mice, Knockout  Organelles  Osmosis  Pinocytosis  Sodium  Transient Receptor Potential Channels  Vacuoles  
Pulmonary surfactant-biomimetic nanoparticles potentiate heterosubtypic influenza immunity 期刊论文
, 2020, 卷号: 367, 期号: 6480
作者:  Wang J.;  Li P.;  Yu Y.;  Fu Y.;  Jiang H.;  Lu M.;  Sun Z.;  Jiang S.;  Lu L.;  Wu M.X.
收藏  |  浏览/下载:32/0  |  提交时间:2020/07/28
2',3' cyclic guanosine monophosphate adenosine monophosphate  influenza vaccine  interferon  nanoparticle  pulmonary surfactant biomimetic nanoparticle  purine nucleotide  surfactant protein A  surfactant protein D  unclassified drug  cell  drug resistance  immune response  immunity  induced response  influenza  nanoparticle  rodent  surfactant  vaccine  animal cell  animal experiment  animal model  animal tissue  Article  CD8+ T lymphocyte  cellular immunity  controlled study  cross protection  cytokine response  drug efficacy  drug safety  drug synthesis  female  human  humoral immunity  hydrophilicity  immune response  immunopathology  immunosurveillance  influenza  innate immunity  lung alveolus epithelium cell  lung alveolus macrophage  mouse  Mustela putorius furo  nanoencapsulation  nonhuman  priority journal  Mus  Mustela  
The human tumor microbiome is composed of tumor type-specific intracellular bacteria 期刊论文
, 2020, 卷号: 368, 期号: 6494
作者:  Nejman D.;  Livyatan I.;  Fuks G.;  Gavert N.;  Zwang Y.;  Geller L.T.;  Rotter-Maskowitz A.;  Weiser R.;  Mallel G.;  Gigi E.;  Meltser A.;  Douglas G.M.;  Kamer I.;  Gopalakrishnan V.;  Dadosh T.;  Levin-Zaidman S.;  Avnet S.;  Atlan T.;  Cooper Z.A.;  Arora R.;  Cogdill A.P.;  Khan M.A.W.;  Ologun G.;  Bussi Y.;  Weinberger A.;  Lotan-Pompan M.;  Golani O.;  Perry G.;  Rokah M.;  Bahar-Shany K.;  Rozeman E.A.;  Blank C.U.;  Ronai A.;  Shaoul R.;  Amit A.;  Dorfman T.;  Kremer R.;  Cohen Z.R.;  Harnof S.;  Siegal T.;  Yehuda-Shnaidman E.;  Gal-Yam E.N.;  Shapira H.;  Baldini N.;  Langille M.G.I.;  Ben-Nun A.;  Kaufman B.;  Nissan A.;  Golan T.;  Dadiani M.;  Levanon K.;  Bar J.;  Yust S.;  Barshack I.;  Peeper D.S.;  Raz D.J.;  Segal E.;  Wargo J.A.;  Sandbank J.;  Shental N.;  Straussman R.
收藏  |  浏览/下载:31/0  |  提交时间:2020/07/28
bacterium  cell  microorganism  tumor  RNA 16S  bacterium  breast  classification  colon  female  genetics  human  immunotherapy  isolation and purification  lung  macrophage  male  microbiology  microflora  neoplasm  ovary  Bacteria  Breast  Colon  Female  Humans  Immunotherapy  Lung  Macrophages  Male  Microbiota  Neoplasms  Ovary  RNA, Ribosomal, 16S