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The anti-liver fibrosis effect of Tibetan medicine (Qiwei Tiexie capsule) is related to the inhibition of NLRP3 inflammasome activation in vivo and in vitro 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2024, 卷号: 319
作者:  Wang, Shanshan;  Ye, Fei;  Ren, Qingjia;  Sun, Shengnan;  Xia, Weina;  Wang, Zhuwei;  Guo, Haolin;  Li, Han;  Zhang, Shujing;  Lowe, Scott;  Chen, Meng;  Du, Qinghong;  Li, Weihong
收藏  |  浏览/下载：10/0  |  提交时间：2024/03/01
Tibetan medicine  Qiwei tiexie capsule  Liver fibrosis  Inflammation  NLRP3 inflammasome  
TAX1BP1 protects against myocardial infarction-associated cardiac anomalies through inhibition of inflammasomes in a RNF34/MAVS/NLRP3-dependent manner 期刊论文
Science Bulletin, 2021, 卷号: 66, 期号: 16
作者:  Xu H.;  Yu W.;  Sun S.;  Li C.;  Ren J.;  Zhang Y.
收藏  |  浏览/下载：15/0  |  提交时间：2021/09/01
Acute myocardial infarction  Autophagic degradation  Mitochondrial antiviral signaling protein  NLRP3 inflammasome  RNF34  TAX1BP1  
IL-18 maintains the homeostasis of mucosal immune system via inflammasome-independent but microbiota-dependent manner 期刊论文
Science Bulletin, 2021
作者:  Zheng X.;  Liu L.;  Meng G.;  Zhu S.;  Zhou R.;  Jiang W.
收藏  |  浏览/下载：27/0  |  提交时间：2021/09/01
Dysbiosis  IL-18  Immune system  Inflammasome  
N-salicyloyl tryptamine derivatives as potential therapeutic agents for Alzheimer's disease with neuroprotective effects 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 115
作者:  Bai, Yinliang;  Liu, Dan;  Zhang, Honghua;  Wang, Yuying;  Wang, Degui;  Cai, Hongbin;  Wen, Huaixiu;  Yuan, Guoqiang;  An, Hui;  Wang, Yali;  Shi, Tao;  Wang, Zhen
收藏  |  浏览/下载：31/0  |  提交时间：2022/04/28
CELL-DEATH  INFLAMMASOME  PYROPTOSIS  NEUROINFLAMMATION  MICROGLIA  MECHANISM  APOPTOSIS  
CFLIPL protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation 期刊论文
, 2020, 卷号: 367, 期号: 6484
作者:  Muendlein H.I.;  Jetton D.;  Connolly W.M.;  Eidell K.P.;  Magri Z.;  Smirnova I.;  Poltorak A.
收藏  |  浏览/下载：37/0  |  提交时间：2020/07/28
FLICE inhibitory protein  interleukin 1beta  lipopolysaccharide  messenger RNA  succinate dehydrogenase (ubiquinone)  Casp1 protein, mouse  caspase 8  Cflar protein, mouse  cryopyrin  FLICE inhibitory protein  IL1B protein, mouse  inflammasome  interleukin 1beta  interleukin 1beta converting enzyme  lipopolysaccharide  succinate dehydrogenase (ubiquinone)  cell  enzyme activity  inhibition  maturation  protein  animal cell  animal experiment  Article  bone marrow derived macrophage  cell death  cell protection  complex formation  controlled study  cytokine release  in vitro study  inflammation  mouse  nonhuman  priority journal  protein analysis  protein degradation  protein function  protein interaction  pyroptosis  animal  gene knockdown  genetics  immunology  macrophage  macrophage activation  metabolism  physiology  Murinae  Animals  CASP8 and FADD-Like Apoptosis Regulating Protein  Caspase 1  Caspase 8  Electron Transport Complex II  Gene Knockdown Techniques  Inflammasomes  Interleukin-1beta  Lipopolysaccharides  Macrophage Activation  Macrophages  Mice  NLR Family, Pyrin Domain-Containing 3 Protein  Pyroptosis