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Structural basis of Gs and Gi recognition by the human glucagon receptor 期刊论文
, 2020, 卷号: 367, 期号: 6484
作者:  Qiao A.;  Han S.;  Li X.;  Li Z.;  Zhao P.;  Dai A.;  Chang R.;  Tai L.;  Tan Q.;  Chu X.;  Ma L.;  Thorsen T.S.;  Reedtz-Runge S.;  Yang D.;  Wang M.-W.;  Sexton P.M.;  Wootten D.;  Sun F.;  Zhao Q.;  Wu B.
收藏  |  浏览/下载：31/0  |  提交时间：2020/07/28
cyclic AMP  glucagon  glucagon receptor  inhibitory guanine nucleotide binding protein  stimulatory guanine nucleotide binding protein  glucagon receptor  inhibitory guanine nucleotide binding protein  protein binding  stimulatory guanine nucleotide binding protein  chemical binding  enzyme activity  gene expression  mutagenicity  protein  alpha helix  Article  binding affinity  carboxy terminal sequence  conformational transition  cryoelectron microscopy  human  molecular recognition  mutagenesis  priority journal  protein binding  protein function  protein protein interaction  protein structure  signal transduction  binding site  chemistry  metabolism  molecular model  protein conformation  ultrastructure  Binding Sites  Cryoelectron Microscopy  Glucagon  GTP-Binding Protein alpha Subunits, Gi-Go  GTP-Binding Protein alpha Subunits, Gs  Humans  Models, Molecular  Protein Binding  Protein Conformation  Protein Conformation, alpha-Helical  Receptors, Glucagon  Signal Transduction  
Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS-coronavirus 2 期刊论文
, 2020, 卷号: 368, 期号: 6494
作者:  Shi J.;  Wen Z.;  Zhong G.;  Yang H.;  Wang C.;  Huang B.;  Liu R.;  He X.;  Shuai L.;  Sun Z.;  Zhao Y.;  Liu P.;  Liang L.;  Cui P.;  Wang J.;  Zhang X.;  Guan Y.;  Tan W.;  Wu G.;  Chen H.;  Bu Z.;  Bu Z.
收藏  |  浏览/下载：32/0  |  提交时间：2020/07/28
bat  canid  disease control  disease transmission  felid  global perspective  infectious disease  poultry  severe acute respiratory syndrome  viral disease  virus  China  Hubei  Wuhan  Anas  Animalia  Canis familiaris  Coronavirus  Gallus gallus  Mustela  SARS coronavirus  Suidae  virus antibody  virus RNA  animal  Betacoronavirus  blood  cat  chicken  Coronavirus infection  disease model  disease predisposition  dog  domestic animal  duck  feces  female  immunology  isolation and purification  male  Mustela putorius furo  pandemic  physiology  pig  respiratory system  species difference  virology  virus attachment  virus pneumonia  virus replication  Animals  Animals, Domestic  Antibodies, Viral  Betacoronavirus  Cats  Chickens  Coronavirus Infections  Disease Models, Animal  Disease Susceptibility  Dogs  Ducks  Feces  Female  Ferrets  Male  Pandemics  Pneumonia, Viral  Respiratory System  RNA, Viral  Species Specificity  Sus scrofa  Virus Attachment  Virus Replication  
A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者:  Wu Y.;  Wang F.;  Shen C.;  Peng W.;  Li D.;  Zhao C.;  Li Z.;  Li S.;  Bi Y.;  Yang Y.;  Gong Y.;  Xiao H.;  Fan Z.;  Tan S.;  Wu G.;  Tan W.;  Lu X.;  Fan C.;  Wang Q.;  Liu Y.;  Zhang C.;  Qi J.;  Gao G.F.;  Gao F.;  Liu L.
收藏  |  浏览/下载：29/0  |  提交时间：2020/07/28
Coronavirus  angiotensin converting enzyme 2  coronavirus spike glycoprotein  dipeptidyl carboxypeptidase  epitope  monoclonal antibody  neutralizing antibody  virus antibody  virus receptor  animal  chemistry  Coronavirus infection  disease model  human  immunology  isolation and purification  lung  mouse  pandemic  protein domain  serodiagnosis  virology  virus load  virus pneumonia  Animals  Antibodies, Monoclonal  Antibodies, Neutralizing  Antibodies, Viral  Coronavirus Infections  Disease Models, Animal  Humans  Immunodominant Epitopes  Lung  Mice  Neutralization Tests  Pandemics  Peptidyl-Dipeptidase A  Pneumonia, Viral  Protein Domains  Receptors, Virus  Spike Glycoprotein, Coronavirus  Viral Load