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Comprehensive Analyses and Prioritization of Tox21 10K Chemicals Affecting Mitochondrial Function by in-Depth Mechanistic Studies 期刊论文
ENVIRONMENTAL HEALTH PERSPECTIVES, 2018, 卷号: 126, 期号: 7
作者:  Xia, Menghang;  Huang, Ruili;  Shi, Qiang;  Boyd, Windy A.;  Zhao, Jinghua;  Sun, Nuo;  Rice, Julie R.;  Dunlap, Paul E.;  Hackstadt, Amber J.;  Bridge, Matt F.;  Smith, Marjolein V.;  Dai, Sheng;  Zheng, Wei;  Chu, Pei-Hsuan;  Gerhold, David;  Witt, Kristine L.;  DeVito, Michael;  Freedman, Jonathan H.;  Austin, Christopher P.;  Houck, Keith A.;  Thomas, Russell S.;  Paules, Richard S.;  Tice, Raymond R.;  Simeonov, Anton
收藏  |  浏览/下载:57/0  |  提交时间:2019/05/04
Identifying environmental chemicals as agonists of the androgen receptor by using a quantitative high-throughput screening platform 期刊论文
TOXICOLOGY, 2017, 卷号: 385, 页码: 48-58
作者:  Lynch, Caitlin;  Sakamuru, Srilatha;  Huang, Ruili;  Stavreva, Diana A.;  Varticovski, Lyuba;  Hager, Gordon L.;  Judson, Richard S.;  Houck, Keith A.;  Kleinstreuer, Nicole C.;  Casey, Warren;  Paules, Richard S.;  Simeonov, Anton;  Xia, Menghang
收藏  |  浏览/下载:35/0  |  提交时间:2019/05/04
Development and Validation of a Computational Model for Androgen Receptor Activity 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2017, 卷号: 30, 期号: 4, 页码: 946-964
作者:  Kleinstreuer, Nicole C.;  Ceger, Patricia;  Watt, Eric D.;  Martin, Matthew;  Houck, Keith;  Browne, Patience;  Thomas, Russell S.;  Casey, Warren M.;  Dix, David J.;  Allen, David;  Sakamuru, Srilatha;  Xia, Menghang;  Huang, Ruili;  Judson, Richard
收藏  |  浏览/下载:34/0  |  提交时间:2019/05/04
Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space 期刊论文
TOXICOLOGICAL SCIENCES, 2016, 卷号: 152, 期号: 2, 页码: 323-339
作者:  Judson, Richard;  Houck, Keith;  Martin, Matt;  Richard, Ann M.;  Knudsen, Thomas B.;  Shah, Imran;  Little, Stephen;  Wambaugh, John;  Setzer, R. Woodrow;  Kothya, Parth;  Phuong, Jimmy;  Filer, Dayne;  Smith, Doris;  Reif, David;  Rotroff, Daniel;  Kleinstreuer, Nicole;  Sipes, Nisha;  Xia, Menghang;  Huang, Ruili;  Crofton, Kevin;  Thomas, Russell S.
收藏  |  浏览/下载:34/0  |  提交时间:2019/05/04
Integrated Model of Chemical Perturbations of a Biological Pathway Using 18 In Vitro High-Throughput Screening Assays for the Estrogen Receptor 期刊论文
TOXICOLOGICAL SCIENCES, 2015, 卷号: 148, 期号: 1, 页码: 137-154
作者:  Judson, Richard S.;  Magpantay, Felicia Maria;  Chickarmane, Vijay;  Haskell, Cymra;  Tania, Nessy;  Taylor, Jean;  Xia, Menghang;  Huang, Ruili;  Rotroff, Daniel M.;  Filer, Dayne L.;  Houck, Keith A.;  Martin, Matthew T.;  Sipes, Nisha;  Richard, Ann M.;  Mansouri, Kamel;  Setzer, R. Woodrow;  Knudsen, Thomas B.;  Crofton, Kevin M.;  Thomas, Russell S.
收藏  |  浏览/下载:49/0  |  提交时间:2019/05/04
Profiling of the Tox21 Chemical Collection for Mitochondrial Function to Identify Compounds that Acutely Decrease Mitochondrial Membrane Potential 期刊论文
ENVIRONMENTAL HEALTH PERSPECTIVES, 2015, 卷号: 123, 期号: 1, 页码: 49-56
作者:  Attene-Ramos, Matias S.;  Huang, Ruili;  Michael, Sam;  Witt, Kristine L.;  Richard, Ann;  Tice, Raymond R.;  Simeonov, Anton;  Austin, Christopher P.;  Xia, Menghang
收藏  |  浏览/下载:32/0  |  提交时间:2019/05/04
Predictive Endocrine Testing in the 21st Century Using in Vitro Assays of Estrogen Receptor Signaling Responses 期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2014, 卷号: 48, 期号: 15, 页码: 8706-8716
作者:  Rotroff, Daniel M.;  Martin, Matt T.;  Dix, David J.;  Filer, Dayne L.;  Houck, Keith A.;  Knudsen, Thomas B.;  Sipes, Nisha S.;  Reif, David M.;  Xia, Menghang;  Huang, Ruili;  Judson, Richard S.
收藏  |  浏览/下载:40/0  |  提交时间:2019/05/04
Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway 期刊论文
SCIENTIFIC REPORTS, 2014, 卷号: 4
作者:  Huang, Ruili;  Sakamuru, Srilatha;  Martin, Matt T.;  Reif, David M.;  Judson, Richard S.;  Houck, Keith A.;  Casey, Warren;  Hsieh, Jui-Hua;  Shockley, Keith R.;  Ceger, Patricia;  Fostel, Jennifer;  Witt, Kristine L.;  Tong, Weida;  Rotroff, Daniel M.;  Zhao, Tongan;  Shinn, Paul;  Simeonov, Anton;  Dix, David J.;  Austin, Christopher P.;  Kavlock, Robert J.;  Tice, Raymond R.;  Xia, Menghang
收藏  |  浏览/下载:41/0  |  提交时间:2019/05/04
Systematic Study of Mitochondria! Toxicity of Environmental Chemicals Using Quantitative High Throughput Screening 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2013, 卷号: 26, 期号: 9, 页码: 1323-1332
作者:  Attene-Ramos, Matias S.;  Huang, Ruili;  Sakamuru, Srilatha;  Witt, Kristine L.;  Beeson, Gyda C.;  Shou, Louie;  Schnellmann, Rick G.;  Beeson, Craig C.;  Tice, Raymond R.;  Austin, Christopher P.;  Xia, Menghang
收藏  |  浏览/下载:14/0  |  提交时间:2019/05/04
The Tox21 robotic platform for the assessment of environmental chemicals - from vision to reality 期刊论文
DRUG DISCOVERY TODAY, 2013, 卷号: 18, 期号: 15-16, 页码: 716-723
作者:  Attene-Ramos, Matias S.;  Miller, Nicole;  Huang, Ruili;  Michael, Sam;  Itkin, Misha;  Kavlock, Robert J.;  Austin, Christopher P.;  Shinn, Paul;  Simeonov, Anton;  Tice, Raymond R.;  Xia, Menghang
收藏  |  浏览/下载:25/0  |  提交时间:2019/05/04