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A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者:  Wu Y.;  Wang F.;  Shen C.;  Peng W.;  Li D.;  Zhao C.;  Li Z.;  Li S.;  Bi Y.;  Yang Y.;  Gong Y.;  Xiao H.;  Fan Z.;  Tan S.;  Wu G.;  Tan W.;  Lu X.;  Fan C.;  Wang Q.;  Liu Y.;  Zhang C.;  Qi J.;  Gao G.F.;  Gao F.;  Liu L.
收藏  |  浏览/下载：33/0  |  提交时间：2020/07/28
Coronavirus  angiotensin converting enzyme 2  coronavirus spike glycoprotein  dipeptidyl carboxypeptidase  epitope  monoclonal antibody  neutralizing antibody  virus antibody  virus receptor  animal  chemistry  Coronavirus infection  disease model  human  immunology  isolation and purification  lung  mouse  pandemic  protein domain  serodiagnosis  virology  virus load  virus pneumonia  Animals  Antibodies, Monoclonal  Antibodies, Neutralizing  Antibodies, Viral  Coronavirus Infections  Disease Models, Animal  Humans  Immunodominant Epitopes  Lung  Mice  Neutralization Tests  Pandemics  Peptidyl-Dipeptidase A  Pneumonia, Viral  Protein Domains  Receptors, Virus  Spike Glycoprotein, Coronavirus  Viral Load  
Cheap shots 期刊论文
, 2020, 卷号: 367, 期号: 6476
作者:  Hand E.
收藏  |  浏览/下载：20/0  |  提交时间：2020/07/28
hemoglobin  hydrogen  myoglobin  crystallization  crystallography  electron microscopy  molecular ecology  protein  X-ray analysis  Article  automation  cost benefit analysis  cost control  cryoelectron microscopy  crystal structure  crystallization  electron  freezing  priority journal  protein analysis  protein purification  protein structure  scientist  structure analysis  X ray crystallography  
Synthesis of proteins by automated flow chemistry 期刊论文
, 2020, 卷号: 368, 期号: 6494
作者:  Hartrampf N.;  Saebi A.;  Poskus M.;  Gates Z.P.;  Callahan A.J.;  Cowfer A.E.;  Hanna S.;  Antilla S.;  Schissel C.K.;  Quartararo A.J.;  Ye X.;  Mijalis A.J.;  Simon M.D.;  Loas A.;  Liu S.;  Jessen C.;  Nielsen T.E.;  Pentelute B.L.
收藏  |  浏览/下载：41/0  |  提交时间：2020/07/28
amino acid  cell component  chemistry  instrumentation  peptide  protein  purification  peptide  protein  chemistry  isolation and purification  procedures  protein domain  protein folding  solid phase synthesis  synthesis  Peptides  Protein Domains  Protein Folding  Proteins  Solid-Phase Synthesis Techniques  
Structural basis for strand-transfer inhibitor binding to HIV intasomes 期刊论文
, 2020, 卷号: 367, 期号: 6479
作者:  Passos D.O.;  Li M.;  Jóźwik I.K.;  Zhao X.Z.;  Santos-Martins D.;  Yang R.;  Smith S.J.;  Jeon Y.;  Forli S.;  Hughes S.H.;  Burke T.R.;  Jr.;  Craigie R.;  Lyumkis D.
收藏  |  浏览/下载：27/0  |  提交时间：2020/07/28
bictegravir  nucleoprotein  protein intasome  unclassified drug  viral protein  bictegravir  fused heterocyclic rings  integrase  integrase inhibitor  multiprotein complex  naphthyridine derivative  nucleoprotein  biochemistry  chemical binding  human immunodeficiency virus  inhibitor  protein  ultrastructure  amino terminal sequence  Article  carboxy terminal sequence  catalysis  cryoelectron microscopy  drug design  drug efficacy  drug protein binding  drug resistance  drug structure  enzyme active site  human  Human immunodeficiency virus infection  nonhuman  priority journal  protein purification  protein structure  antiviral resistance  chemistry  drug effect  genetics  Human immunodeficiency virus  virus DNA cell DNA interaction  Cryoelectron Microscopy  Drug Design  Drug Resistance, Viral  Heterocyclic Compounds, 4 or More Rings  HIV  HIV Integrase  HIV Integrase Inhibitors  Humans  Multiprotein Complexes  Naphthyridines  Nucleoproteins  Virus Integration