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Microenvironment mapping via Dexter energy transfer on immune cells 期刊论文
, 2020, 卷号: 367, 期号: 6482
作者:  Geri J.B.;  Oakley J.V.;  Reyes-Robles T.;  Wang T.;  McCarver S.J.;  White C.H.;  Rodriguez-Rivera F.P.;  Parker D.L.;  Hett E.C.;  Fadeyi O.O.;  Oslund R.C.;  MacMillan D.W.C.
收藏  |  浏览/下载:33/0  |  提交时间:2020/07/28
antibody conjugate  carbene  programmed death 1 ligand 1  methane  programmed death 1 ligand 1  antibody  catalysis  catalyst  cell component  detection method  enzyme  enzyme activity  protein  antigen binding  Article  cell membrane  energy transfer  human  immunocompetent cell  immunological synapse  lymphocyte  photocatalysis  priority journal  protein analysis  protein protein interaction  tumor microenvironment  catalysis  chemistry  energy transfer  Jurkat cell line  metabolism  photochemistry  procedures  radiation response  ultraviolet radiation  B7-H1 Antigen  Catalysis  Cell Membrane  Cellular Microenvironment  Energy Transfer  Humans  Jurkat Cells  Lymphocytes  Methane  Photochemical Processes  Protein Interaction Mapping  Protein Interaction Maps  Ultraviolet Rays  
Critical differences in 3D atomic structure of individual ligand-protected nanocrystals in solution 期刊论文
, 2020, 卷号: 368, 期号: 6486
作者:  Kim B.H.;  Heo J.;  Kim S.;  Reboul C.F.;  Chun H.;  Kang D.;  Bae H.;  Hyun H.;  Lim J.;  Lee H.;  Han B.;  Hyeon T.;  Paul Alivisatos A.;  Ercius P.;  Elmlund H.;  Park J.
收藏  |  浏览/下载:42/0  |  提交时间:2020/07/28
ligand  nanocrystal  platinum nanoparticle  crystal structure  electron microscopy  lattice dynamics  ligand  nanoparticle  three-dimensional modeling  Article  atom  catalysis  chemical binding  chemical composition  chemical procedures  concentration (parameter)  crystal structure  degradation  electron microscopy  image analysis  liquid crystal  nanoanalysis  priority journal  structure analysis  surface property  synthesis  
Molecular mechanism of biased signaling in a prototypical G protein-coupled receptor 期刊论文
, 2020, 卷号: 367, 期号: 6480
作者:  Suomivuori C.-M.;  Latorraca N.R.;  Wingler L.M.;  Eismann S.;  King M.C.;  Kleinhenz A.L.W.;  Skiba M.A.;  Staus D.P.;  Kruse A.C.;  Lefkowitz R.J.;  Dror R.O.
收藏  |  浏览/下载:18/0  |  提交时间:2020/07/28
angiotensin 1 receptor  beta arrestin 1  beta arrestin 2  G protein coupled receptor  rhodopsin  chemical binding  design method  ligand  molecular analysis  protein  signaling  allosterism  Article  carboxy terminal sequence  conformational transition  controlled study  crystal structure  human  ligand binding  molecular dynamics  priority journal  protein conformation  signal transduction  structural model  
Determination of the melanocortin-4 receptor structure identifies Ca2+ as a cofactor for ligand binding 期刊论文
, 2020, 卷号: 368, 期号: 6489
作者:  Yu J.;  Gimenez L.E.;  Hernandez C.C.;  Wu Y.;  Wein A.H.;  Han G.W.;  McClary K.;  Mittal S.R.;  Burdsall K.;  Stauch B.;  Wu L.;  Stevens S.N.;  Peisley A.;  Williams S.Y.;  Chen V.;  Millhauser G.L.;  Zhao S.;  Cone R.D.;  Stevens R.C.
收藏  |  浏览/下载:30/0  |  提交时间:2020/07/28
alpha intermedin  calcium ion  cyclic AMP  G protein coupled receptor  heterotrimeric guanine nucleotide binding protein  inwardly rectifying potassium channel  inwardly rectifying potassium channel subunit Kir7.1  melanocortin 4 receptor  n acetyl alpha intermedin[4-10]cyclo[4 norleucine 5 aspartic acid 7 [3 (2 naphthyl)alanine] 10 lysinamide]  unclassified drug  calcium  G protein coupled receptor  intermedin  inwardly rectifying potassium channel  Kir7.1 channel  ligand  melanocortin 4 receptor  n acetyl alpha intermedin[4-10]cyclo[4 norleucine 5 aspartic acid 7 [3 (2 naphthyl)alanine] 10 lysinamide]  protein binding  calcium  chemical binding  homeostasis  hormone  ligand  obesity  peptide  protein  Article  binding affinity  complex formation  crystallization  drug structure  extracellular calcium  human  ligand binding  priority journal  protein structure  receptor blocking  signal transduction  chemistry  genetics  mutation  protein multimerization  protein secondary structure  X ray crystallography  Calcium  Crystallography, X-Ray  Cyclic AMP  Humans  Ligands  Melanocyte-Stimulating Hormones  Mutation  Potassium Channels, Inwardly Rectifying  Protein Binding  Protein Multimerization  Protein Structure, Secondary  Receptor, Melanocortin, Type 4  Receptors, G-Protein-Coupled  Signal Transduction