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A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV 期刊论文
, 2020, 卷号: 368, 期号: 6491
作者:  Yuan M.;  Wu N.C.;  Zhu X.;  Lee C.-C.D.;  So R.T.Y.;  Lv H.;  Mok C.K.P.;  Wilson I.A.
收藏  |  浏览/下载：26/0  |  提交时间：2020/07/28
angiotensin converting enzyme 2  epitope  neutralizing antibody  virus hemagglutinin  virus spike protein  angiotensin converting enzyme 2  coronavirus receptors  coronavirus spike glycoprotein  dipeptidyl carboxypeptidase  epitope  neutralizing antibody  spike glycoprotein, SARS-CoV  spike protein, SARS-CoV-2  virus antibody  virus antigen  virus receptor  antibody  antigen  chemical binding  crystal structure  protein  respiratory disease  viral disease  virus  amino terminal sequence  antibody isolation  antigen binding  antigenicity  Article  binding affinity  binding site  conservation biology  controlled study  coronavirus disease 2019  cross reaction  cryoelectron microscopy  crystal structure  enzyme linked immunosorbent assay  epidemic  glycosylation  human  hydrophobicity  immune response  in vitro study  in vivo study  light chain  nonhuman  priority journal  protein conformation  protein domain  protein interaction  protein localization  protein structure  protein targeting  receptor binding  SARS coronavirus  Severe acute respiratory syndrome coronavirus 2  amino acid sequence  antibody affinity  Betacoronavirus  binding site  chemistry  immunology  metabolism  molecular model  SARS coronavirus  X ray crystallography  Coronavirus  SARS coronavirus  Amino Acid Sequence  Antibodies, Neutralizing  Antibodies, Viral  Antibody Affinity  Antigens, Viral  Betacoronavirus  Binding Sites  Cross Reactions  Crystallography, X-Ray  Epitopes  Models, Molecular  Peptidyl-Dipeptidase A  Protein Conformation  Protein Domains  Protein Interaction Domains and Motifs  Receptors, Virus  SARS Virus  Spike Glycoprotein, Coronavirus  
Golgi-derived PI(4)P-containing vesicles drive late steps of mitochondrial division 期刊论文
, 2020, 卷号: 367, 期号: 6484
作者:  Nagashima S.;  Tábara L.-C.;  Tilokani L.;  Paupe V.;  Anand H.;  Pogson J.H.;  Zunino R.;  McBride H.M.;  Prudent J.
收藏  |  浏览/下载：36/0  |  提交时间：2020/07/28
adenosine diphosphate ribosylation factor 1  dynamin related protein 1  mitochondrial protein  phosphatidylinositol 4 kinase IIIbeta  phosphatidylinositol 4 phosphate  phosphatidylinositol kinase  unclassified drug  adenosine diphosphate ribosylation factor 1  ARF1 protein, human  DNM1L protein, human  dynamin  phosphatidylinositol 4-phosphate  phosphatidylinositol kinase  polyphosphoinositide  cell component  cell organelle  chemical compound  enzyme  enzyme activity  mitochondrion  protein  Article  controlled study  COS-7 cell line  endoplasmic reticulum  fibroblast  gene silencing  HeLa cell line  human  human cell  membrane microdomain  mitochondrial division  mitochondrial dynamics  mitochondrial scission  priority journal  protein localization  trans Golgi network  U2OS cell line  animal  cell line  Chlorocebus aethiops  CV-1 cell line  genetics  metabolism  mitochondrial membrane  mitochondrion  RNA interference  trans Golgi network  ultrastructure  Mammalia  1-Phosphatidylinositol 4-Kinase  ADP-Ribosylation Factor 1  Animals  Cell Line  Chlorocebus aethiops  COS Cells  Dynamins  Endoplasmic Reticulum  HeLa Cells  Humans  Membrane Microdomains  Mitochondria  Mitochondrial Dynamics  Mitochondrial Membranes  Phosphatidylinositol Phosphates  RNA Interference  trans-Golgi Network  
Ancient origins of allosteric activation in a Ser-Thr kinase 期刊论文
, 2020, 卷号: 367, 期号: 6480
作者:  Hadzipasic A.;  Wilson C.;  Nguyen V.;  Kern N.;  Kim C.;  Pitsawong W.;  Villali J.;  Zheng Y.;  Kern D.
收藏  |  浏览/下载：48/0  |  提交时间：2020/07/28
aurora A kinase  microtubule associated protein  TPX2 protein  unclassified drug  activation energy  ancestry  cell  chemical binding  experimental study  fitness  protein  allosterism  amino acid sequence  Article  binding affinity  binding site  enzyme activation  enzyme activity  enzyme binding  enzyme localization  enzyme phosphorylation  gene duplication  horizontal gene transfer  human  hydrophobicity  intracellular signaling  phylogenetic tree  phylogeny  priority journal  protein binding  protein localization  protein protein interaction