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| Computing cancer's weak spots 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者: Khamsi R.
  收藏 | 浏览/下载：46/0 | 提交时间：2020/07/28
ruxolitinib STAT3 protein antineoplastic agent transcription factor algorithm cancer computer simulation disease treatment drug development medicine Article cancer cell cancer radiotherapy enzyme inhibition gene activity gene expression regulation gene interaction gene mutation gene repression gene targeting human laboratory test malignant neoplasm molecular dynamics nonhuman oncologist priority journal RNA sequencing algorithm genetics mutation neoplasm personalized medicine procedures systems biology Algorithms Antineoplastic Agents Humans Mutation Neoplasms Precision Medicine Systems Biology Transcription Factors |
| Therapeutic targeting of preleukemia cells in a mouse model of NPM1 mutant acute myeloid leukemia 期刊论文
, 2020, 卷号: 367, 期号: 6477
作者: Uckelmann H.J.; Kim S.M.; Wong E.M.; Hatton C.; Giovinazzo H.; Gadrey J.Y.; Krivtsov A.V.; Rücker F.G.; Döhner K.; McGeehan G.M.; Levine R.L.; Bullinger L.; Vassiliou G.S.; Armstrong S.A.
收藏 | 浏览/下载：36/0 | 提交时间：2020/07/28
antileukemic agent methionine unclassified drug vtp 50469 biological development cancer cell disease treatment mutation numerical model oral health acute myeloid leukemia animal cell animal experiment animal model antineoplastic activity Article cell proliferation cell self-renewal chromatin controlled study drug targeting gene gene mutation leukemia cell molecularly targeted therapy mouse mouse model nonhuman NPM1 gene preleukemia priority journal Mus |
| Evolving epidemiology of poliovirus serotype 2 following withdrawal of the serotype 2 oral poliovirus vaccine 期刊论文
, 2020, 卷号: 368, 期号: 6489
作者: Macklin G.R.; O’Reilly K.M.; Grassly N.C.; Edmunds W.J.; Mach O.; Santhana Gopala Krishnan R.; Voorman A.; Vertefeuille J.F.; Abdelwahab J.; Gumede N.; Goel A.; Sosler S.; Sever J.; Bandyopadhyay A.S.; Pallansch M.A.; Nandy R.; Mkanda P.; Diop O.M.; Sutter R.W.
收藏 | 浏览/下载：48/0 | 提交时间：2020/07/28
poliomyelitis vaccine oral poliomyelitis vaccine disease transmission epidemiology immunity vaccine virus acute flaccid paralysis Article disease control disease eradication flaccid paralysis geography health care policy human Human poliovirus 2 immune deficiency immunization incidence intestinal mucosal immunity logistic regression analysis mucosal immunity priority journal public health campaign sanitation statistical model treatment withdrawal virus transmission epidemic global health immunology poliomyelitis Poliomyelitis virus procedures treatment withdrawal Poliovirus Disease Eradication Disease Outbreaks Global Health Humans Poliomyelitis Poliovirus Poliovirus Vaccine, Oral Withholding Treatment |
| Hope for hematological diseases 期刊论文
, 2020, 卷号: 367, 期号: 6483
作者: Wilkinson A.C.
收藏 | 浏览/下载：41/0 | 提交时间：2020/07/28
fibronectin polyvinyl alcohol serum albumin stem cell factor thrombopoietin blood disease incidence disease treatment laboratory method medicine public health Article cell differentiation cell self-renewal chemotherapy CRISPR-CAS9 system ex vivo study gene editing gene therapy genotoxicity graft versus host reaction hematologic disease hematopoiesis hematopoietic stem cell transplantation human morbidity mortality multipotent stem cell nonhuman priority journal radiotherapy stem cell culture stem cell expansion |
| Total synthesis of the complex taxane diterpene canataxpropellane 期刊论文
, 2020, 卷号: 367, 期号: 6478
作者: Schneider F.; Samarin K.; Zanella S.; Gaich T.
收藏 | 浏览/下载：34/0 | 提交时间：2020/07/28
canataxpropellane diterpenoid siloxane taxane derivative unclassified drug cancer chemical analysis chemical bonding disease treatment medicine terpene Article chirality cycloaddition Diels Alder reaction drug structure drug synthesis enantioselectivity photooxidation priority journal stereoselectivity Alnus |
| Starving the Enemy? Feeding Behavior Shapes Host-Parasite Interactions 期刊论文
, 2020, 卷号: 35, 期号: 1
作者: Hite J.L.; Pfenning A.C.; Cressler C.E.
收藏 | 浏览/下载：34/0 | 提交时间：2020/07/28
disease treatment foraging behavior host-parasite interaction infectivity interdisciplinary approach symptom virulence animal ecology evolution feeding behavior host parasite interaction parasite virulence Animals Biological Evolution Ecology Feeding Behavior Host-Parasite Interactions Parasites Virulence |
