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Computing cancer's weak spots 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者:  Khamsi R.
收藏  |  浏览/下载:36/0  |  提交时间:2020/07/28
ruxolitinib  STAT3 protein  antineoplastic agent  transcription factor  algorithm  cancer  computer simulation  disease treatment  drug development  medicine  Article  cancer cell  cancer radiotherapy  enzyme inhibition  gene activity  gene expression regulation  gene interaction  gene mutation  gene repression  gene targeting  human  laboratory test  malignant neoplasm  molecular dynamics  nonhuman  oncologist  priority journal  RNA sequencing  algorithm  genetics  mutation  neoplasm  personalized medicine  procedures  systems biology  Algorithms  Antineoplastic Agents  Humans  Mutation  Neoplasms  Precision Medicine  Systems Biology  Transcription Factors  
Therapeutic targeting of preleukemia cells in a mouse model of NPM1 mutant acute myeloid leukemia 期刊论文
, 2020, 卷号: 367, 期号: 6477
作者:  Uckelmann H.J.;  Kim S.M.;  Wong E.M.;  Hatton C.;  Giovinazzo H.;  Gadrey J.Y.;  Krivtsov A.V.;  Rücker F.G.;  Döhner K.;  McGeehan G.M.;  Levine R.L.;  Bullinger L.;  Vassiliou G.S.;  Armstrong S.A.
收藏  |  浏览/下载:27/0  |  提交时间:2020/07/28
antileukemic agent  methionine  unclassified drug  vtp 50469  biological development  cancer  cell  disease treatment  mutation  numerical model  oral health  acute myeloid leukemia  animal cell  animal experiment  animal model  antineoplastic activity  Article  cell proliferation  cell self-renewal  chromatin  controlled study  drug targeting  gene  gene mutation  leukemia cell  molecularly targeted therapy  mouse  mouse model  nonhuman  NPM1 gene  preleukemia  priority journal  Mus  
Evolving epidemiology of poliovirus serotype 2 following withdrawal of the serotype 2 oral poliovirus vaccine 期刊论文
, 2020, 卷号: 368, 期号: 6489
作者:  Macklin G.R.;  O’Reilly K.M.;  Grassly N.C.;  Edmunds W.J.;  Mach O.;  Santhana Gopala Krishnan R.;  Voorman A.;  Vertefeuille J.F.;  Abdelwahab J.;  Gumede N.;  Goel A.;  Sosler S.;  Sever J.;  Bandyopadhyay A.S.;  Pallansch M.A.;  Nandy R.;  Mkanda P.;  Diop O.M.;  Sutter R.W.
收藏  |  浏览/下载:40/0  |  提交时间:2020/07/28
poliomyelitis vaccine  oral poliomyelitis vaccine  disease transmission  epidemiology  immunity  vaccine  virus  acute flaccid paralysis  Article  disease control  disease eradication  flaccid paralysis  geography  health care policy  human  Human poliovirus 2  immune deficiency  immunization  incidence  intestinal mucosal immunity  logistic regression analysis  mucosal immunity  priority journal  public health campaign  sanitation  statistical model  treatment withdrawal  virus transmission  epidemic  global health  immunology  poliomyelitis  Poliomyelitis virus  procedures  treatment withdrawal  Poliovirus  Disease Eradication  Disease Outbreaks  Global Health  Humans  Poliomyelitis  Poliovirus  Poliovirus Vaccine, Oral  Withholding Treatment  
Hope for hematological diseases 期刊论文
, 2020, 卷号: 367, 期号: 6483
作者:  Wilkinson A.C.
收藏  |  浏览/下载:35/0  |  提交时间:2020/07/28
fibronectin  polyvinyl alcohol  serum albumin  stem cell factor  thrombopoietin  blood  disease incidence  disease treatment  laboratory method  medicine  public health  Article  cell differentiation  cell self-renewal  chemotherapy  CRISPR-CAS9 system  ex vivo study  gene editing  gene therapy  genotoxicity  graft versus host reaction  hematologic disease  hematopoiesis  hematopoietic stem cell transplantation  human  morbidity  mortality  multipotent stem cell  nonhuman  priority journal  radiotherapy  stem cell culture  stem cell expansion  
Total synthesis of the complex taxane diterpene canataxpropellane 期刊论文
, 2020, 卷号: 367, 期号: 6478
作者:  Schneider F.;  Samarin K.;  Zanella S.;  Gaich T.
收藏  |  浏览/下载:26/0  |  提交时间:2020/07/28
canataxpropellane  diterpenoid  siloxane  taxane derivative  unclassified drug  cancer  chemical analysis  chemical bonding  disease treatment  medicine  terpene  Article  chirality  cycloaddition  Diels Alder reaction  drug structure  drug synthesis  enantioselectivity  photooxidation  priority journal  stereoselectivity  Alnus  
Starving the Enemy? Feeding Behavior Shapes Host-Parasite Interactions 期刊论文
, 2020, 卷号: 35, 期号: 1
作者:  Hite J.L.;  Pfenning A.C.;  Cressler C.E.
收藏  |  浏览/下载:28/0  |  提交时间:2020/07/28
disease treatment  foraging behavior  host-parasite interaction  infectivity  interdisciplinary approach  symptom  virulence  animal  ecology  evolution  feeding behavior  host parasite interaction  parasite  virulence  Animals  Biological Evolution  Ecology  Feeding Behavior  Host-Parasite Interactions  Parasites  Virulence