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A phage-encoded anti-CRISPR enables complete evasion of type VI-A CRISPR-Cas immunity 期刊论文
, 2020, 卷号: 369, 期号: 6499
作者:  Meeske A.J.;  Jia N.;  Cassel A.K.;  Kozlova A.;  Liao J.;  Wiedmann M.;  Patel D.J.;  Marraffini L.A.
收藏  |  浏览/下载:33/0  |  提交时间:2020/07/28
CRISPR associated protein  endonuclease  guide RNA  viral protein  virus RNA  bacteriophage  clustered regularly interspaced short palindromic repeat  CRISPR Cas system  DNA cleavage  genetics  Listeria  metabolism  RNA stability  virology  Bacteriophages  Clustered Regularly Interspaced Short Palindromic Repeats  CRISPR-Associated Proteins  CRISPR-Cas Systems  DNA Cleavage  Endonucleases  Listeria  RNA Stability  RNA, Guide  RNA, Viral  Viral Proteins  
CRISPR-engineered T cells in patients with refractory cancer 期刊论文
, 2020, 卷号: 367, 期号: 6481
作者:  Stadtmauer E.A.;  Fraietta J.A.;  Davis M.M.;  Cohen A.D.;  Weber K.L.;  Lancaster E.;  Mangan P.A.;  Kulikovskaya I.;  Gupta M.;  Chen F.;  Tian L.;  Gonzalez V.E.;  Xu J.;  Jung I.-Y.;  Joseph Melenhorst J.;  Plesa G.;  Shea J.;  Matlawski T.;  Cervini A.;  Gaymon A.L.;  Desjardins S.;  Lamontagne A.;  Salas-Mckee J.;  Fesnak A.;  Siegel D.L.;  Levine B.L.;  Jadlowsky J.K.;  Young R.M.;  Chew A.;  Hwang W.-T.;  Hexner E.O.;  Carreno B.M.;  Nobles C.L.;  Bushman F.D.;  Parker K.R.;  Qi Y.;  Satpathy A.T.;  Chang H.Y.;  Zhao Y.;  Lacey S.F.;  June C.H.
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heterodimer  programmed death 1 receptor  T lymphocyte receptor alpha chain  T lymphocyte receptor beta chain  cancer  cell  gene  gene expression  genetic engineering  immunity  protein  adult  aged  Article  cancer patient  cell engineering  chromosome translocation  clinical article  clustered regularly interspaced short palindromic repeat  controlled study  CRISPR-CAS9 system  feasibility study  female  gene editing  gene expression  gene frequency  gene locus  genetic code  human  human cell  male  middle aged  myeloma  PDCD1 gene  phase 1 clinical trial  priority journal  sarcoma  T lymphocyte  TRAC gene  TRBC gene  tumor immunity  
Pervasive functional translation of noncanonical human open reading frames 期刊论文
, 2020, 卷号: 367, 期号: 6482
作者:  Chen J.;  Brunner A.-D.;  Cogan J.Z.;  Nuñez J.K.;  Fields A.P.;  Adamson B.;  Itzhak D.N.;  Li J.Y.;  Mann M.;  Leonetti M.D.;  Weissman J.S.
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messenger RNA  antigen  cell component  cell organelle  chemical binding  growth  phenotype  protein  Quaternary  RNA  Article  cell function  cell growth  cellular distribution  clustered regularly interspaced short palindromic repeat  gene sequence  genetic screening  HLA system  human  non-canonical base pairing  open reading frame  operon  priority journal  protein analysis  protein binding  protein function  transcriptomics  translation regulation  Mammalia