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PE/PPE proteins mediate nutrient transport across the outer membrane of Mycobacterium tuberculosis 期刊论文
, 2020, 卷号: 367, 期号: 6482
作者:  Wang Q.;  Boshoff H.I.M.;  Harrison J.R.;  Ray P.C.;  Green S.R.;  Wyatt P.G.;  Barry Iii C.E.
收藏  |  浏览/下载：21/0  |  提交时间：2020/07/28
3,3 bis di(methylsulfonyl)propionamide  antiinfective agent  bacterial protein  glucose  glycerol  magnesium  phosphate  propionamide derivative  protein proline proline glutamate  protein proline proline glutamate 51  unclassified drug  amide  bacterial protein  lipid  phthiocerol dimycocerosate  propionamide  thiol derivative  cell component  chemical compound  membrane  mutation  protein  tuberculosis  antibiotic resistance  Article  bacterial cell  bacterial cell wall  bacterial growth  bacterial outer membrane  cell division  drug structure  Mycobacterium tuberculosis  nonhuman  nutrient uptake  priority journal  protein depletion  cell membrane  cell membrane permeability  chemistry  drug effect  gene deletion  genetics  metabolism  transport at the cellular level  Mycobacterium tuberculosis  Amides  Bacterial Proteins  Biological Transport  Cell Membrane  Cell Membrane Permeability  Drug Resistance, Bacterial  Gene Deletion  Glucose  Glycerol  Lipids  Mycobacterium tuberculosis  Sulfhydryl Compounds  
The body's dangerous defenders 期刊论文
, 2020, 卷号: 367, 期号: 6482
作者:  Leslie M.
收藏  |  浏览/下载：32/0  |  提交时间：2020/07/28
alvelestat  avacopan  chemokine receptor CXCR2  danirixin  leukocyte elastase  n [2 (2,3 difluorobenzylthio) 6 (2,3 dihydroxy 1 methylpropoxy) 4 pyrimidinyl] 1 azetidinesulfonamide  nemiralisib  simvastatin  leukocyte elastase inhibitor  antimicrobial activity  apoptosis  cell  enzyme activity  physiological response  ANCA associated vasculitis  Article  autoimmune disease  autoimmunity  bacterial pneumonia  bactericidal activity  bronchiolitis obliterans  drug targeting  extracellular matrix  extracellular trap  hematopoietic stem cell transplantation  human  immunity  immunocompetent cell  infection  inflammation  lung disease  neutrophil  neutrophil chemotaxis  nonhuman  priority journal  risk factor  sepsis  single cell RNA seq  autoimmune disease  chronic obstructive lung disease  clinical trial (topic)  drug effect  enzymology  immunology  lung tumor  neutrophil  Autoimmune Diseases  Clinical Trials as Topic  Humans  Lung Neoplasms  Neutrophils  Proteinase Inhibitory Proteins, Secretory  Pulmonary Disease, Chronic Obstructive  
Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者:  Zhang L.;  Zhao Y.;  Gao Y.;  Wu L.;  Gao R.;  Zhang Q.;  Wang Y.;  Wu C.;  Wu F.;  Gurcha S.S.;  Veerapen N.;  Batt S.M.;  Zhao W.;  Qin L.;  Yang X.;  Wang M.;  Zhu Y.;  Zhang B.;  Bi L.;  Zhang X.;  Yang H.;  Guddat L.W.;  Xu W.;  Wang Q.;  Li J.;  Besra G.S.;  Rao Z.
收藏  |  浏览/下载：29/0  |  提交时间：2020/07/28
biochemistry  cell component  chemical binding  detection method  drug  drug resistance  enzyme  enzyme activity  inhibition  mutation  Mycobacterium tuberculosis  arabinosyltransferase  ethambutol  glycosyltransferase  tuberculostatic agent  cell wall  chemistry  cryoelectron microscopy  enzymology  multidrug resistance  Mycobacterium tuberculosis  protein conformation  Antitubercular Agents  Cell Wall  Cryoelectron Microscopy  Drug Resistance, Multiple, Bacterial  Ethambutol  Mycobacterium tuberculosis  Pentosyltransferases  Protein Conformation  
Cell position fates and collective fountain flow in bacterial biofilms revealed by light-sheet microscopy 期刊论文
, 2020, 卷号: 369, 期号: 6499
作者:  Qin B.;  Fei C.;  Bridges A.A.;  Mashruwala A.A.;  Stone H.A.;  Wingreen N.S.;  Bassler B.L.
收藏  |  浏览/下载：18/0  |  提交时间：2020/07/28
bacterial protein  scleroprotein  biofilm  cytology  genetics  metabolism  microscopy  motion  mutation  physiology  procedures  single cell analysis  Vibrio cholerae  Bacterial Proteins  Biofilms  Extracellular Matrix Proteins  Microscopy  Motion  Mutation  Single-Cell Analysis  Vibrio cholerae  
Structure of V-ATPase from the mammalian brain 期刊论文
, 2020, 卷号: 367, 期号: 6483
作者:  Abbas Y.M.;  Wu D.;  Bueler S.A.;  Robinson C.V.;  Rubinstein J.L.
收藏  |  浏览/下载：15/0  |  提交时间：2020/07/28
adenosine triphosphatase  neurotransmitter  proton  renin  unclassified drug  vacuolar type adenosine triphosphatase  Atp6ap1 protein, rat  ATP6AP2 protein, rat  bacterial protein  biological marker  cell surface receptor  proton transporting adenosine triphosphate synthase  blood  brain  catalysis  catalyst  enzyme  enzyme activity  membrane  protein  Article  axon  blood pressure regulation  brain tissue  catalysis  chemical structure  cryoelectron microscopy  electrolyte balance  electron microscopy  human  hydrolysis  Legionella pneumophila  molecular docking  nerve cell  neurotransmitter uptake  nonhuman  priority journal  protein structure  signal transduction  Wnt signaling  yeast  animal  biocatalysis  brain  cell membrane  chemical model  chemistry  enzymology  protein domain  rat  renin angiotensin aldosterone system  Legionella pneumophila  Mammalia  Rattus  Animals  Bacterial Proteins  Biocatalysis  Biomarkers  Brain  Cell Membrane  Cryoelectron Microscopy  Models, Chemical  Protein Domains  Rats  Receptors, Cell Surface  Renin-Angiotensin System  Vacuolar Proton-Translocating ATPases  Wnt Signaling Pathway