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Characterization, estimation of virulence and drug resistance of diarrheagenic escherichia coli (DEC) isolated from Tibetan pigs 期刊论文
MICROBIAL PATHOGENESIS, 2023, 卷号: 177
作者:  Cao, Zhipeng;  Qi, Ming;  Shang, Peng;  Zhang, Hui;  Nawaz, Shah;  Ghaffar, Abdul;  Wu, Qingxia;  Dong, Hailong
收藏  |  浏览/下载：7/0  |  提交时间：2024/03/01
Tibetan pig  Escherichia coli  Virulence  Drug resistance  
The Evolution and Transmission Dynamics of Multidrug-Resistant Tuberculosis in an Isolated High-Plateau Population of Tibet, China 期刊论文
MICROBIOLOGY SPECTRUM, 2023, 卷号: 11, 期号: 2
作者:  Jiang, Qi;  Liu, Hai-Can;  Liu, Qing-Yun;  Phelan, Jody E.;  Tao, Feng-Xi;  Zhao, Xiu-Qin;  Wang, Jian;  Glynn, Judith R.;  Takiff, Howard E.;  Clark, Taane G.;  Wan, Kang-Lin;  Gao, Qian
收藏  |  浏览/下载：20/0  |  提交时间：2024/03/01
tuberculosis  multidrug-resistant tuberculosis (MDR-TB)  whole-genome sequencing (WGS)  drug resistance  evolution  
Berberine reverses multidrug resistance in Candida albicans by hijacking the drug efflux pump Mdr1p 期刊论文
Science Bulletin, 2021
作者:  Tong Y.;  Zhang J.;  Sun N.;  Wang X.-M.;  Wei Q.;  Zhang Y.;  Huang R.;  Pu Y.;  Dai H.;  Ren B.;  Pei G.;  Song F.;  Zhu G.;  Wang X.;  Xia X.;  Chen X.;  Jiang L.;  Wang S.;  Ouyang L.;  Xie N.;  Zhang B.;  Jiang Y.;  Liu X.;  Calderone R.;  Bai F.;  Zhang L.;  Alterovitz G.
收藏  |  浏览/下载：53/0  |  提交时间：2021/09/01
Berberine  Candida albicans  Drug excretion transporter  Mitochondria  Multidrug-resistance  
BSC2 induces multidrug resistance via contributing to the formation of biofilm in Saccharomyces cerevisiae 期刊论文
CELLULAR MICROBIOLOGY, 2021, 卷号: 23, 期号: 12
作者:  Huang, Zhiwei;  Dai, Hongsheng;  Zhang, Xiaoyu;  Wang, Qiao;  Sun, Jing;  Deng, Yunxia;  Shi, Ping
收藏  |  浏览/下载：32/0  |  提交时间：2022/04/28
CELL-WALL  DRUG-RESISTANCE  CANDIDA-ALBICANS  YEAST  PROTEIN  GENES  GLYCOSYLATION  MANNOSYLATION  FLOCCULATION  EXPRESSION  
PE/PPE proteins mediate nutrient transport across the outer membrane of Mycobacterium tuberculosis 期刊论文
, 2020, 卷号: 367, 期号: 6482
作者:  Wang Q.;  Boshoff H.I.M.;  Harrison J.R.;  Ray P.C.;  Green S.R.;  Wyatt P.G.;  Barry Iii C.E.
收藏  |  浏览/下载：28/0  |  提交时间：2020/07/28
3,3 bis di(methylsulfonyl)propionamide  antiinfective agent  bacterial protein  glucose  glycerol  magnesium  phosphate  propionamide derivative  protein proline proline glutamate  protein proline proline glutamate 51  unclassified drug  amide  bacterial protein  lipid  phthiocerol dimycocerosate  propionamide  thiol derivative  cell component  chemical compound  membrane  mutation  protein  tuberculosis  antibiotic resistance  Article  bacterial cell  bacterial cell wall  bacterial growth  bacterial outer membrane  cell division  drug structure  Mycobacterium tuberculosis  nonhuman  nutrient uptake  priority journal  protein depletion  cell membrane  cell membrane permeability  chemistry  drug effect  gene deletion  genetics  metabolism  transport at the cellular level  Mycobacterium tuberculosis  Amides  Bacterial Proteins  Biological Transport  Cell Membrane  Cell Membrane Permeability  Drug Resistance, Bacterial  Gene Deletion  Glucose  Glycerol  Lipids  Mycobacterium tuberculosis  Sulfhydryl Compounds  
Effect of tolerance on the evolution of antibiotic resistance under drug combinations 期刊论文
, 2020, 卷号: 367, 期号: 6474
作者:  Liu J.;  Gefen O.;  Ronin I.;  Bar-Meir M.;  Balaban N.Q.
收藏  |  浏览/下载：18/0  |  提交时间：2020/07/28
daptomycin  rifampicin  vancomycin  antiinfective agent  beta' subunit of RNA polymerase  daptomycin  DNA directed RNA polymerase  rifampicin  vancomycin  antibiotic resistance  bacterium  emergence  evolutionary biology  experimental study  laboratory method  survival  adult  antibiotic resistance  Article  bacterial mutation  bacterial strain  bacterium isolation  clinical article  colony forming unit  combination drug therapy  drug effect  drug tolerance  human  in vitro study  minimum inhibitory concentration  nonhuman  phylogeny  priority journal  Staphylococcus aureus  whole genome sequencing  antibiotic resistance  combination drug therapy  drug effect  genetics  methicillin resistant Staphylococcus aureus  microbial sensitivity test  microbiology  molecular evolution  mutation  single nucleotide polymorphism  Staphylococcus infection  Staphylococcus aureus  Anti-Bacterial Agents  Daptomycin  DNA-Directed RNA Polymerases  Drug Resistance, Microbial  Drug Therapy, Combination  Evolution, Molecular  Humans  Methicillin-Resistant Staphylococcus aureus  Microbial Sensitivity Tests  Mutation  Polymorphism, Single Nucleotide  Rifampin  Staphylococcal Infections  Vancomycin  
Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者:  Zhang L.;  Zhao Y.;  Gao Y.;  Wu L.;  Gao R.;  Zhang Q.;  Wang Y.;  Wu C.;  Wu F.;  Gurcha S.S.;  Veerapen N.;  Batt S.M.;  Zhao W.;  Qin L.;  Yang X.;  Wang M.;  Zhu Y.;  Zhang B.;  Bi L.;  Zhang X.;  Yang H.;  Guddat L.W.;  Xu W.;  Wang Q.;  Li J.;  Besra G.S.;  Rao Z.
收藏  |  浏览/下载：42/0  |  提交时间：2020/07/28
biochemistry  cell component  chemical binding  detection method  drug  drug resistance  enzyme  enzyme activity  inhibition  mutation  Mycobacterium tuberculosis  arabinosyltransferase  ethambutol  glycosyltransferase  tuberculostatic agent  cell wall  chemistry  cryoelectron microscopy  enzymology  multidrug resistance  Mycobacterium tuberculosis  protein conformation  Antitubercular Agents  Cell Wall  Cryoelectron Microscopy  Drug Resistance, Multiple, Bacterial  Ethambutol  Mycobacterium tuberculosis  Pentosyltransferases  Protein Conformation  
Pulmonary surfactant-biomimetic nanoparticles potentiate heterosubtypic influenza immunity 期刊论文
, 2020, 卷号: 367, 期号: 6480
作者:  Wang J.;  Li P.;  Yu Y.;  Fu Y.;  Jiang H.;  Lu M.;  Sun Z.;  Jiang S.;  Lu L.;  Wu M.X.
收藏  |  浏览/下载：45/0  |  提交时间：2020/07/28
2',3' cyclic guanosine monophosphate adenosine monophosphate  influenza vaccine  interferon  nanoparticle  pulmonary surfactant biomimetic nanoparticle  purine nucleotide  surfactant protein A  surfactant protein D  unclassified drug  cell  drug resistance  immune response  immunity  induced response  influenza  nanoparticle  rodent  surfactant  vaccine  animal cell  animal experiment  animal model  animal tissue  Article  CD8+ T lymphocyte  cellular immunity  controlled study  cross protection  cytokine response  drug efficacy  drug safety  drug synthesis  female  human  humoral immunity  hydrophilicity  immune response  immunopathology  immunosurveillance  influenza  innate immunity  lung alveolus epithelium cell  lung alveolus macrophage  mouse  Mustela putorius furo  nanoencapsulation  nonhuman  priority journal  Mus  Mustela  
A Kelch13-defined endocytosis pathway mediates artemisinin resistance in malaria parasites 期刊论文
, 2020, 卷号: 367, 期号: 6473
作者:  Birnbaum J.;  Scharf S.;  Schmidt S.;  Jonscher E.;  Maria Hoeijmakers W.A.;  Flemming S.;  Toenhake C.G.;  Schmitt M.;  Sabitzki R.;  Bergmann B.;  Fröhlke U.;  Mesén-Ramírez P.;  Soares A.B.;  Herrmann H.;  Bártfai R.;  Spielmann T.
收藏  |  浏览/下载：40/0  |  提交时间：2020/07/28
artemisinin  artemisinin derivative  cytosol receptor  hemoglobin  protein Kelch13  protozoal protein  unclassified drug  antimalarial agent  cell  drug resistance  hemoglobin  malaria  mutation  physiology  protein  antimalarial drug resistance  Article  controlled study  endocytosis  gene inactivation  gene mutation  host cell  Kelch13 gene  nonhuman  Plasmodium  priority journal  protein analysis  protein function  
Structural basis for strand-transfer inhibitor binding to HIV intasomes 期刊论文
, 2020, 卷号: 367, 期号: 6479
作者:  Passos D.O.;  Li M.;  Jóźwik I.K.;  Zhao X.Z.;  Santos-Martins D.;  Yang R.;  Smith S.J.;  Jeon Y.;  Forli S.;  Hughes S.H.;  Burke T.R.;  Jr.;  Craigie R.;  Lyumkis D.
收藏  |  浏览/下载：28/0  |  提交时间：2020/07/28
bictegravir  nucleoprotein  protein intasome  unclassified drug  viral protein  bictegravir  fused heterocyclic rings  integrase  integrase inhibitor  multiprotein complex  naphthyridine derivative  nucleoprotein  biochemistry  chemical binding  human immunodeficiency virus  inhibitor  protein  ultrastructure  amino terminal sequence  Article  carboxy terminal sequence  catalysis  cryoelectron microscopy  drug design  drug efficacy  drug protein binding  drug resistance  drug structure  enzyme active site  human  Human immunodeficiency virus infection  nonhuman  priority journal  protein purification  protein structure  antiviral resistance  chemistry  drug effect  genetics  Human immunodeficiency virus  virus DNA cell DNA interaction  Cryoelectron Microscopy  Drug Design  Drug Resistance, Viral  Heterocyclic Compounds, 4 or More Rings  HIV  HIV Integrase  HIV Integrase Inhibitors  Humans  Multiprotein Complexes  Naphthyridines  Nucleoproteins  Virus Integration