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Hydrophobic zeolite modification for in situ peroxide formation in methane oxidation to methanol 期刊论文
, 2020, 卷号: 367, 期号: 6474
作者:  Jin Z.;  Wang L.;  Zuidema E.;  Mondal K.;  Zhang M.;  Zhang J.;  Wang C.;  Meng X.;  Yang H.;  Mesters C.;  Xiao F.-S.
收藏  |  浏览/下载：213/0  |  提交时间：2020/07/28
aluminosilicate zeolite  carbon dioxide  carbon monoxide  formaldehyde  gold nanoparticle  hydrogen peroxide  methane  methanol  palladium nanoparticle  silicon dioxide  unclassified drug  zeolite  aluminosilicate  catalyst  diffusion  hydrogen  hydrogen peroxide  methane  methanol  oxidation  oxygen  Article  carbon nuclear magnetic resonance  catalyst  chemical reaction  concentration (parameter)  diffusion  energy dispersive X ray spectroscopy  Fourier transform infrared spectroscopy  hydrophobicity  isotherm  nanoencapsulation  nuclear magnetic resonance  oxidation  priority journal  scanning electron microscopy  silicon nuclear magnetic resonance  stoichiometry  synthesis  transmission electron microscopy  X ray crystallography  
Structure and selectivity engineering of the M1 muscarinic receptor toxin complex 期刊论文
, 2020, 卷号: 369, 期号: 6500
作者:  Maeda S.;  Xu J.;  N Kadji F.M.;  Clark M.J.;  Zhao J.;  Tsutsumi N.;  Aoki J.;  Sunahara R.K.;  Inoue A.;  Garcia K.C.;  Kobilka B.K.
收藏  |  浏览/下载：54/0  |  提交时间：2020/07/28
atropine  m1-toxin  muscarinic M1 receptor  muscarinic receptor blocking agent  snake venom  animal  chemistry  genetic engineering  genetics  protein conformation  Sf9 cell line  X ray crystallography  Animals  Atropine  Crystallography, X-Ray  Elapid Venoms  Genetic Engineering  Muscarinic Antagonists  Protein Conformation  Receptor, Muscarinic M1  Sf9 Cells  
Valence and patterning of aromatic residues determine the phase behavior of prion-like domains 期刊论文
, 2020, 卷号: 367, 期号: 6478
作者:  Martin E.W.;  Holehouse A.S.;  Peran I.;  Farag M.;  Incicco J.J.;  Bremer A.;  Grace C.R.;  Soranno A.;  Pappu R.V.;  Mittag T.
收藏  |  浏览/下载：21/0  |  提交时间：2020/07/28
aromatic hydrocarbon  biophysics  concentration (composition)  genetic analysis  nuclear magnetic resonance  prion disease  protein  separation  temperature effect  article  nonhuman  nuclear magnetic resonance spectroscopy  phase separation  prediction  prion  simulation  X ray crystallography  amino acid sequence  chemistry  phase transition  prion  protein domain  small angle scattering  X ray diffraction  heterogeneous nuclear ribonucleoprotein A1  phenylalanine  tyrosine  Amino Acid Sequence  Heterogeneous Nuclear Ribonucleoprotein A1  Magnetic Resonance Spectroscopy  Phase Transition  Phenylalanine  Prions  Protein Domains  Scattering, Small Angle  Tyrosine  X-Ray Diffraction  
A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV 期刊论文
, 2020, 卷号: 368, 期号: 6491
作者:  Yuan M.;  Wu N.C.;  Zhu X.;  Lee C.-C.D.;  So R.T.Y.;  Lv H.;  Mok C.K.P.;  Wilson I.A.
收藏  |  浏览/下载：25/0  |  提交时间：2020/07/28
angiotensin converting enzyme 2  epitope  neutralizing antibody  virus hemagglutinin  virus spike protein  angiotensin converting enzyme 2  coronavirus receptors  coronavirus spike glycoprotein  dipeptidyl carboxypeptidase  epitope  neutralizing antibody  spike glycoprotein, SARS-CoV  spike protein, SARS-CoV-2  virus antibody  virus antigen  virus receptor  antibody  antigen  chemical binding  crystal structure  protein  respiratory disease  viral disease  virus  amino terminal sequence  antibody isolation  antigen binding  antigenicity  Article  binding affinity  binding site  conservation biology  controlled study  coronavirus disease 2019  cross reaction  cryoelectron microscopy  crystal structure  enzyme linked immunosorbent assay  epidemic  glycosylation  human  hydrophobicity  immune response  in vitro study  in vivo study  light chain  nonhuman  priority journal  protein conformation  protein domain  protein interaction  protein localization  protein structure  protein targeting  receptor binding  SARS coronavirus  Severe acute respiratory syndrome coronavirus 2  amino acid sequence  antibody affinity  Betacoronavirus  binding site  chemistry  immunology  metabolism  molecular model  SARS coronavirus  X ray crystallography  Coronavirus  SARS coronavirus  Amino Acid Sequence  Antibodies, Neutralizing  Antibodies, Viral  Antibody Affinity  Antigens, Viral  Betacoronavirus  Binding Sites  Cross Reactions  Crystallography, X-Ray  Epitopes  Models, Molecular  Peptidyl-Dipeptidase A  Protein Conformation  Protein Domains  Protein Interaction Domains and Motifs  Receptors, Virus  SARS Virus  Spike Glycoprotein, Coronavirus  
De novo design of protein logic gates 期刊论文
, 2020, 卷号: 368, 期号: 6486
作者:  Chen Z.;  Kibler R.D.;  Hunt A.;  Busch F.;  Pearl J.;  Jia M.;  VanAernum Z.L.;  Wicky B.I.M.;  Dods G.;  Liao H.;  Wilken M.S.;  Ciarlo C.;  Green S.;  El-Samad H.;  Stamatoyannopoulos J.;  Wysocki V.H.;  Jewett M.C.;  Boyken S.E.;  Baker D.
收藏  |  浏览/下载：31/0  |  提交时间：2020/07/28
cell  design method  gene expression  genetic analysis  protein  activation domain  Article  binding affinity  circular dichroism  controlled study  de novo design  design  DNA binding motif  enzyme activity  genetic transcription  human  human cell  hydrogen bond  hydrophobicity  mass spectrometry  native mass spectrometry  nonhuman  priority journal  protein protein interaction  protein structure  RNA translation  stoichiometry  thermodynamics  two hybrid system  X ray crystallography  chemistry  genetics  logic  metabolism  protein analysis  protein engineering  protein processing  synthetic biology  T lymphocyte  yeast  HAVCR2 protein, human  hepatitis A virus cellular receptor 2  Hepatitis A Virus Cellular Receptor 2  Humans  Logic  Mass Spectrometry  Protein Engineering  Protein Interaction Maps  Protein Processing, Post-Translational  Synthetic Biology  T-Lymphocytes  Transcription, Genetic  Yeasts  
Total synthesis reveals atypical atropisomerism in a small-molecule natural product, tryptorubin A 期刊论文
, 2020, 卷号: 367, 期号: 6476
作者:  Reisberg S.H.;  Gao Y.;  Walker A.S.;  Helfrich E.J.N.;  Clardy J.;  Baran P.S.
收藏  |  浏览/下载：43/0  |  提交时间：2020/07/28
alkaloid  tryptorubin A  unclassified drug  alkaloid  connectivity  molecular analysis  peptide  alkylation  Article  bioinformatics  carbon nuclear magnetic resonance  chemical structure  chirality  cyclization  dehydrogenation  high performance liquid chromatography  hydrogen bond  hydrophobicity  isomerism  nonhuman  nuclear magnetic resonance spectroscopy  oxidation  priority journal  protein processing  proton nuclear magnetic resonance  stereochemistry  Streptomyces  synthesis  X ray crystallography  
Cheap shots 期刊论文
, 2020, 卷号: 367, 期号: 6476
作者:  Hand E.
收藏  |  浏览/下载：20/0  |  提交时间：2020/07/28
hemoglobin  hydrogen  myoglobin  crystallization  crystallography  electron microscopy  molecular ecology  protein  X-ray analysis  Article  automation  cost benefit analysis  cost control  cryoelectron microscopy  crystal structure  crystallization  electron  freezing  priority journal  protein analysis  protein purification  protein structure  scientist  structure analysis  X ray crystallography  
Structural evidence for a dynamic metallocofactor during N2 reduction by Mo-nitrogenase 期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:  Kang W.;  Lee C.C.;  Jasniewski A.J.;  Ribbe M.W.;  Hu Y.
收藏  |  浏览/下载：48/0  |  提交时间：2020/07/28
ammonia  catalysis  crystal structure  enzyme activity  ligand  physiological response  sulfur  ligand  molybdenum iron protein  nitrogen  sulfur  Azotobacter vinelandii  biocatalysis  chemistry  enzymology  oxidation reduction reaction  protein multimerization  X ray crystallography  Azotobacter vinelandii  Biocatalysis  Crystallography, X-Ray  Ligands  Molybdoferredoxin  Nitrogen  Oxidation-Reduction  Protein Multimerization  Sulfur  
Determination of the melanocortin-4 receptor structure identifies Ca2+ as a cofactor for ligand binding 期刊论文
, 2020, 卷号: 368, 期号: 6489
作者:  Yu J.;  Gimenez L.E.;  Hernandez C.C.;  Wu Y.;  Wein A.H.;  Han G.W.;  McClary K.;  Mittal S.R.;  Burdsall K.;  Stauch B.;  Wu L.;  Stevens S.N.;  Peisley A.;  Williams S.Y.;  Chen V.;  Millhauser G.L.;  Zhao S.;  Cone R.D.;  Stevens R.C.
收藏  |  浏览/下载：38/0  |  提交时间：2020/07/28
alpha intermedin  calcium ion  cyclic AMP  G protein coupled receptor  heterotrimeric guanine nucleotide binding protein  inwardly rectifying potassium channel  inwardly rectifying potassium channel subunit Kir7.1  melanocortin 4 receptor  n acetyl alpha intermedin[4-10]cyclo[4 norleucine 5 aspartic acid 7 [3 (2 naphthyl)alanine] 10 lysinamide]  unclassified drug  calcium  G protein coupled receptor  intermedin  inwardly rectifying potassium channel  Kir7.1 channel  ligand  melanocortin 4 receptor  n acetyl alpha intermedin[4-10]cyclo[4 norleucine 5 aspartic acid 7 [3 (2 naphthyl)alanine] 10 lysinamide]  protein binding  calcium  chemical binding  homeostasis  hormone  ligand  obesity  peptide  protein  Article  binding affinity  complex formation  crystallization  drug structure  extracellular calcium  human  ligand binding  priority journal  protein structure  receptor blocking  signal transduction  chemistry  genetics  mutation  protein multimerization  protein secondary structure  X ray crystallography  Calcium  Crystallography, X-Ray  Cyclic AMP  Humans  Ligands  Melanocyte-Stimulating Hormones  Mutation  Potassium Channels, Inwardly Rectifying  Protein Binding  Protein Multimerization  Protein Structure, Secondary  Receptor, Melanocortin, Type 4  Receptors, G-Protein-Coupled  Signal Transduction  
Democratizing cryo-EM: Broadening access to an expanding field 期刊论文
, 2020, 卷号: 367, 期号: 6484
作者:  Tachibana C.
收藏  |  浏览/下载：180/0  |  提交时间：2020/07/28
membrane protein  nucleic acid  democratization  detection method  electron microscopy  algorithm  Article  conformational transition  cryoelectron microscopy  crystallization  electron diffraction  electron tomography  freezing  glycosylation  human  microcrystal electron diffraction  nanoimaging  nuclear magnetic resonance spectroscopy  priority journal  protein processing  protein structure  protein synthesis  social welfare  transmission electron microscopy  X ray crystallography