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Comprehensive Analyses and Prioritization of Tox21 10K Chemicals Affecting Mitochondrial Function by in-Depth Mechanistic Studies 期刊论文
ENVIRONMENTAL HEALTH PERSPECTIVES, 2018, 卷号: 126, 期号: 7
作者:  Xia, Menghang;  Huang, Ruili;  Shi, Qiang;  Boyd, Windy A.;  Zhao, Jinghua;  Sun, Nuo;  Rice, Julie R.;  Dunlap, Paul E.;  Hackstadt, Amber J.;  Bridge, Matt F.;  Smith, Marjolein V.;  Dai, Sheng;  Zheng, Wei;  Chu, Pei-Hsuan;  Gerhold, David;  Witt, Kristine L.;  DeVito, Michael;  Freedman, Jonathan H.;  Austin, Christopher P.;  Houck, Keith A.;  Thomas, Russell S.;  Paules, Richard S.;  Tice, Raymond R.;  Simeonov, Anton
收藏  |  浏览/下载:69/0  |  提交时间:2019/05/04
Identifying environmental chemicals as agonists of the androgen receptor by using a quantitative high-throughput screening platform 期刊论文
TOXICOLOGY, 2017, 卷号: 385, 页码: 48-58
作者:  Lynch, Caitlin;  Sakamuru, Srilatha;  Huang, Ruili;  Stavreva, Diana A.;  Varticovski, Lyuba;  Hager, Gordon L.;  Judson, Richard S.;  Houck, Keith A.;  Kleinstreuer, Nicole C.;  Casey, Warren;  Paules, Richard S.;  Simeonov, Anton;  Xia, Menghang
收藏  |  浏览/下载:48/0  |  提交时间:2019/05/04
Alternative approaches for identifying acute systemic toxicity: Moving from research to regulatory testing 期刊论文
TOXICOLOGY IN VITRO, 2017, 卷号: 41, 页码: 245-259
作者:  Hamm, Jon;  Sullivan, Kristie;  Clippinger, Amy J.;  Strickland, Judy;  Bell, Shannon;  Bhhatarai, Barun;  Blaauboer, Bas;  Casey, Warren;  Dorman, David;  Forsby, Anna;  Garcia-Reyero, Natalia;  Gehen, Sean;  Graepel, Rabea;  Hotchkiss, Jon;  Lowit, Anna;  Matheson, Joanna;  Reaves, Elissa;  Scarano, Louis;  Sprankle, Catherine;  Tunkel, Jay;  Wilson, Dan;  Xia, Menghang;  Zhu, Hao;  Allen, David
收藏  |  浏览/下载:49/0  |  提交时间:2019/05/04
Development and Validation of a Computational Model for Androgen Receptor Activity 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2017, 卷号: 30, 期号: 4, 页码: 946-964
作者:  Kleinstreuer, Nicole C.;  Ceger, Patricia;  Watt, Eric D.;  Martin, Matthew;  Houck, Keith;  Browne, Patience;  Thomas, Russell S.;  Casey, Warren M.;  Dix, David J.;  Allen, David;  Sakamuru, Srilatha;  Xia, Menghang;  Huang, Ruili;  Judson, Richard
收藏  |  浏览/下载:45/0  |  提交时间:2019/05/04
The Next Generation of Risk Assessment Multi-Year Study-Highlights of Findings, Applications to Risk Assessment, and Future Directions 期刊论文
ENVIRONMENTAL HEALTH PERSPECTIVES, 2016, 卷号: 124, 期号: 11, 页码: 1671-1682
作者:  Cote, Ila;  Andersen, Melvin E.;  Ankley, Gerald T.;  Barone, Stanley;  Birnbaum, Linda S.;  Boekelheide, Kim;  Bois, FredericY.;  Burgoon, Lyle D.;  Chiu, Weihsueh A.;  Crawford-Brown, Douglas;  Crofton, Kevin M.;  DeVito, Michael;  Devlin, Robert B.;  Edwards, Stephen W.;  Guyton, Kathryn Z.;  Hattis, Dale;  Judson, Richard S.;  Knight, Derek;  Krewski, Daniel;  Lambert, Jason;  Maull, Elizabeth Anne;  Mendrick, Donna;  Paoli, Gregory M.;  Patel, Chirag Jagdish;  Perkins, Edward J.;  Poje, Gerald;  Portier, Christopher J.;  Rusyn, Ivan;  Schulte, Paul A.;  Simeonov, Anton;  Smith, Martyn T.;  Thayer, Kristina A.;  Thomas, Russell S.;  Thomas, Reuben;  Tice, Raymond R.;  Vandenberg, John J.;  Villeneuve, Daniel L.;  Wesselkamper, Scott;  Whelan, Maurice;  Whittaker, Christine;  White, Ronald;  Xia, Menghang;  Yauk, Carole;  Zeise, Lauren;  Zhao, Jay;  DeWoskin, Robert S.
收藏  |  浏览/下载:57/0  |  提交时间:2019/05/04
Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space 期刊论文
TOXICOLOGICAL SCIENCES, 2016, 卷号: 152, 期号: 2, 页码: 323-339
作者:  Judson, Richard;  Houck, Keith;  Martin, Matt;  Richard, Ann M.;  Knudsen, Thomas B.;  Shah, Imran;  Little, Stephen;  Wambaugh, John;  Setzer, R. Woodrow;  Kothya, Parth;  Phuong, Jimmy;  Filer, Dayne;  Smith, Doris;  Reif, David;  Rotroff, Daniel;  Kleinstreuer, Nicole;  Sipes, Nisha;  Xia, Menghang;  Huang, Ruili;  Crofton, Kevin;  Thomas, Russell S.
收藏  |  浏览/下载:50/0  |  提交时间:2019/05/04
Integrated Model of Chemical Perturbations of a Biological Pathway Using 18 In Vitro High-Throughput Screening Assays for the Estrogen Receptor 期刊论文
TOXICOLOGICAL SCIENCES, 2015, 卷号: 148, 期号: 1, 页码: 137-154
作者:  Judson, Richard S.;  Magpantay, Felicia Maria;  Chickarmane, Vijay;  Haskell, Cymra;  Tania, Nessy;  Taylor, Jean;  Xia, Menghang;  Huang, Ruili;  Rotroff, Daniel M.;  Filer, Dayne L.;  Houck, Keith A.;  Martin, Matthew T.;  Sipes, Nisha;  Richard, Ann M.;  Mansouri, Kamel;  Setzer, R. Woodrow;  Knudsen, Thomas B.;  Crofton, Kevin M.;  Thomas, Russell S.
收藏  |  浏览/下载:61/0  |  提交时间:2019/05/04
Population-Based in Vitro Hazard and Concentration-Response Assessment of Chemicals: The 1000 Genomes High-Throughput Screening Study 期刊论文
ENVIRONMENTAL HEALTH PERSPECTIVES, 2015, 卷号: 123, 期号: 5, 页码: 458-466
作者:  Abdo, Nour;  Xia, Menghang;  Brown, Chad C.;  Kosyk, Oksana;  Huang, Ruili;  Sakamuru, Srilatha;  Zhou, Yi-Hui;  Jack, John R.;  Gallins, Paul;  Xia, Kai;  Li, Yun;  Chiu, Weihsueh A.;  Motsinger-Reif, Alison A.;  Austin, Christopher P.;  Tice, Raymond R.;  Rusyn, Ivan;  Wright, Fred A.
收藏  |  浏览/下载:55/0  |  提交时间:2019/05/04
Profiling of the Tox21 Chemical Collection for Mitochondrial Function to Identify Compounds that Acutely Decrease Mitochondrial Membrane Potential 期刊论文
ENVIRONMENTAL HEALTH PERSPECTIVES, 2015, 卷号: 123, 期号: 1, 页码: 49-56
作者:  Attene-Ramos, Matias S.;  Huang, Ruili;  Michael, Sam;  Witt, Kristine L.;  Richard, Ann;  Tice, Raymond R.;  Simeonov, Anton;  Austin, Christopher P.;  Xia, Menghang
收藏  |  浏览/下载:44/0  |  提交时间:2019/05/04
Quantitative High-Throughput Profiling of Environmental Chemicals and Drugs that Modulate Farnesoid X Receptor 期刊论文
SCIENTIFIC REPORTS, 2014, 卷号: 4
作者:  Hsu, Chia-Wen;  Zhao, Jinghua;  Huang, Ruili;  Hsieh, Jui-Hua;  Hamm, Jon;  Chang, Xiaoqing;  Houck, Keith;  Xia, Menghang
收藏  |  浏览/下载:44/0  |  提交时间:2019/05/04