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Developing and applying the adverse outcome pathway concept for understanding and predicting neurotoxicity 期刊论文
NEUROTOXICOLOGY, 2017, 卷号: 59, 页码: 240-255
作者:  Bal-Price, Anna;  Lein, Pamela J.;  Keil, Kimberly P.;  Sethi, Sunjay;  Shafer, Timothy;  Barenys, Marta;  Fritsche, Ellen;  Sachana, Magdalini;  Meek, M. E. (Bette)
收藏  |  浏览/下载：31/0  |  提交时间：2019/05/04
How Adverse Outcome Pathways Can Aid the Development and Use of Computational Prediction Models for Regulatory Toxicology 期刊论文
TOXICOLOGICAL SCIENCES, 2017, 卷号: 155, 期号: 2, 页码: 326-336
作者:  Wittwehr, Clemens;  Aladjov, Hristo;  Ankley, Gerald;  Byrne, Hugh J.;  de Knecht, Joop;  Heinzle, Elmar;  Klambauer, Guenter;  Landesmann, Brigitte;  Luijten, Mirjam;  MacKay, Cameron;  Maxwell, Gavin;  Meek, M. E. (Bette);  Paini, Alicia;  Perkins, Edward;  Sobanski, Tomasz;  Villeneuve, Dan;  Waters, Katrina M.;  Whelan, Maurice
收藏  |  浏览/下载：34/0  |  提交时间：2019/05/04
Increasing Scientific Confidence in Adverse Outcome Pathways: Application of Tailored Bradford-Hill Considerations for Evaluating Weight of Evidence 期刊论文
REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2015, 卷号: 72, 期号: 3, 页码: 514-537
作者:  Becker, Richard A.;  Ankley, Gerald T.;  Edwards, Stephen W.;  Kennedy, Sean W.;  Linkov, Igor;  Meek, Bette;  Sachana, Magdalini;  Segner, Helmut;  Van der Burg, Bart;  Villeneuve, Daniel L.;  Watanabe, Haruna;  Barton-Maclaren, Tara S.
收藏  |  浏览/下载：20/0  |  提交时间：2019/05/04
Gaining acceptance for the use of in vitro toxicity assays and QIVIVE in regulatory risk assessment 期刊论文
TOXICOLOGY, 2015, 卷号: 332, 页码: 112-123
作者:  Meek, M. E. (Bette);  Lipscomb, John C.
收藏  |  浏览/下载：19/0  |  提交时间：2019/05/04
Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPAR alpha) as a case study 期刊论文
CRITICAL REVIEWS IN TOXICOLOGY, 2014, 卷号: 44, 期号: 1, 页码: 1-49
作者:  Corton, J. Christopher;  Cunningham, Michael L.;  Hummer, B. Timothy;  Lau, Christopher;  Meek, Bette;  Peters, Jeffrey M.;  Popp, James A.;  Rhomberg, Lorenz;  Seed, Jennifer;  Klaunig, James E.
收藏  |  浏览/下载：18/0  |  提交时间：2019/05/04
Incorporating New Technologies Into Toxicity Testing and Risk Assessment: Moving From 21st Century Vision to a Data-Driven Framework 期刊论文
TOXICOLOGICAL SCIENCES, 2013, 卷号: 136, 期号: 1, 页码: 4-18
作者:  Thomas, Russell S.;  Philbert, Martin A.;  Auerbach, Scott S.;  Wetmore, Barbara A.;  Devito, Michael J.;  Cote, Ila;  Rowlands, J. Craig;  Whelan, Maurice P.;  Hays, Sean M.;  Andersen, Melvin E.;  Meek, M. E. (Bette);  Reiter, Lawrence W.;  Lambert, Jason C.;  Clewell, Harvey J., III;  Stephens, Martin L.;  Zhao, Q. Jay;  Wesselkamper, Scott C.;  Flowers, Lynn;  Carney, Edward W.;  Pastoor, Timothy P.;  Petersen, Dan D.;  Yauk, Carole L.;  Nong, Andy
收藏  |  浏览/下载：39/0  |  提交时间：2019/05/04
A framework for fit-for-purpose dose response assessment 期刊论文
REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2013, 卷号: 66, 期号: 2, 页码: 234-240
作者:  Meek, M. E. Bette;  Bolger, Michael;  Bus, James S.;  Christopher, John;  Conolly, Rory B.;  Lewis, R. Jeffrey;  Paolini, Gregory M.;  Schoeny, Rita;  Haber, Lynne T.;  Rosenstein, Amy B.;  Dourson, Michael L.
收藏  |  浏览/下载：29/0  |  提交时间：2019/05/04
Case study illustrating the WHO IPCS guidance on characterization and application of physiologically based pharmacokinetic models in risk assessment 期刊论文
REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2013, 卷号: 66, 期号: 1, 页码: 116-129
作者:  Meek, M. E. (Bette);  Barton, Hugh A.;  Bessems, Jos G.;  Lipscomb, John C.;  Krishnan, Kannan
收藏  |  浏览/下载：16/0  |  提交时间：2019/05/04