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| Measuring infectious SARS-CoV-2 in clinical samples reveals a higher viral titer:RNA ratio for Delta and Epsilon vs. Alpha variants 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2022, 卷号: 119, 期号: 5 作者: Despres H.W.; Mills M.G.; Shirley D.J.; Schmidt M.M.; Huang M.-L.; Roychoudhury P.; Jerome K.R.; Greninger A.L.; Bruce E.A. 收藏  |  浏览/下载:32/0  |  提交时间:2022/02/22 |
| SARS-CoV-2 escape from a highly neutralizing COVID-19 convalescent plasma 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 36 作者: Andreano E.; Piccini G.; Licastro D.; Casalino L.; Johnson N.V.; Paciello I.; Monego S.D.; Pantano E.; Manganaro N.; Manenti A.; Manna R.; Casa E.; Hyseni I.; Benincasa L.; Montomoli E.; Amaro R.E.; McLellan J.S.; Rappuoli R. 收藏  |  浏览/下载:37/0  |  提交时间:2021/11/25 |
| Analysis of SARS-CoV-2 infection dynamic in vivo using reporter-expressing viruses 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 41 作者: Ye C.; Chiem K.; Park J.-G.; Silvas J.A.; Vasquez D.M.; Sourimant J.; Lin M.J.; Greninger A.L.; Plemper R.K.; Torrelles J.B.; Kobie J.J.; Walter M.R.; de la Torre J.C.; Martinez-Sobrido L. 收藏  |  浏览/下载:21/0  |  提交时间:2022/02/22 |
| Widespread remodeling of the m6A RNA-modification landscape by a viral regulator of RNA processing and export 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 30 作者: Srinivas K.P.; Depledge D.P.; Abebe J.S.; Rice S.A.; Mohr I.; Wilson A.C. 收藏  |  浏览/下载:18/0  |  提交时间:2022/02/22 |
| Protease cleavage of RNF20 facilitates coronavirus replication via stabilization of SREBP1 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 37 作者: Zhang S.; Wang J.; Cheng G. 收藏  |  浏览/下载:7/0  |  提交时间:2022/02/22 |
| Generation of sars-cov-2 reporter replicon for high-throughput antiviral screening and testing 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 15 作者: He X.; Quan S.; Xu M.; Rodriguez S.; Goh S.L.; Wei J.; Fridman A.; Koeplinger K.A.; Carroll S.S.; Grobler J.A.; Espeseth A.S.; Olsen D.B.; Hazuda D.J.; Wang D. 收藏  |  浏览/下载:28/0  |  提交时间:2021/05/24 |
| Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 5 作者: Jan J.-T.; Cheng T.-J.R.; Juang Y.-P.; Ma H.-H.; Wu Y.-T.; Yang W.-B.; Cheng C.-W.; Chen X.; Chou T.-H.; Shie J.-J.; Cheng W.-C.; Chein R.-J.; Mao S.-S.; Liang P.-H.; Ma C.; Hung S.-C.; Wong C.-H. 收藏  |  浏览/下载:37/0  |  提交时间:2021/05/24 |
| Bepridil is potent against SARS-CoV-2 in vitro 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 10 作者: Vatansever E.C.; Yang K.S.; Drelich A.K.; Kratch K.C.; Cho C.-C.; Kempaiah K.R.; Hsu J.C.; Mellott D.M.; Xu S.; Tseng C.-T.K.; Liu W.R. 收藏  |  浏览/下载:32/0  |  提交时间:2021/05/24 |
| Free fatty acid binding pocket in the locked structure of SARS-CoV-2 spike protein 期刊论文 Science, 2020, 卷号: 370, 期号: 6517 作者: Toelzer C.; Gupta K.; Yadav S.K.N.; Borucu U.; Davidson A.D.; Williamson M.K.; Shoemark D.K.; Garzoni F.; Staufer O.; Milligan R.; Capin J.; Mulholland A.J.; Spatz J.; Fitzgerald D.; Berger I.; Schaffitzel C. 收藏  |  浏览/下载:19/0  |  提交时间:2022/01/14 |
| Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease 期刊论文 , 2020, 卷号: 368, 期号: 6497 作者: Dai W.; Zhang B.; Jiang X.-M.; Su H.; Li J.; Zhao Y.; Xie X.; Jin Z.; Peng J.; Liu F.; Li C.; Li Y.; Bai F.; Wang H.; Cheng X.; Cen X.; Hu S.; Yang X.; Wang J.; Liu X.; Xiao G.; Jiang H.; Rao Z.; Zhang L.-K.; Xu Y.; Yang H.; Liu H. 收藏  |  浏览/下载:36/0  |  提交时间:2020/07/28 aldehyde antimicrobial activity drug enzyme activity infectivity inhibitor reaction kinetics viral disease Coronavirus SARS coronavirus 3C-like proteinase, Coronavirus antivirus agent cysteine proteinase viral protein animal Betacoronavirus chemical structure chemistry Chlorocebus aethiops Coronavirus infection dog drug design drug effect enzyme active site enzymology female human male mouse pandemic preclinical study protein tertiary structure Sprague Dawley rat toxicity testing Vero cell line virus pneumonia Animals Antiviral Agents Betacoronavirus Catalytic Domain Chlorocebus aethiops Coronavirus Infections Cysteine Endopeptidases Dogs Drug Design Drug Evaluation, Preclinical Female Humans Male Mice Molecular Structure Pandemics Pneumonia, Viral Protein Structure, Tertiary Rats, Sprague-Dawley Toxicity Tests Vero Cells Viral Nonstructural Proteins |