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The anti-liver fibrosis effect of Tibetan medicine (Qiwei Tiexie capsule) is related to the inhibition of NLRP3 inflammasome activation in vivo and in vitro 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2024, 卷号: 319
作者:  Wang, Shanshan;  Ye, Fei;  Ren, Qingjia;  Sun, Shengnan;  Xia, Weina;  Wang, Zhuwei;  Guo, Haolin;  Li, Han;  Zhang, Shujing;  Lowe, Scott;  Chen, Meng;  Du, Qinghong;  Li, Weihong
收藏  |  浏览/下载:14/0  |  提交时间:2024/03/01
Tibetan medicine  Qiwei tiexie capsule  Liver fibrosis  Inflammation  NLRP3 inflammasome  
TAX1BP1 protects against myocardial infarction-associated cardiac anomalies through inhibition of inflammasomes in a RNF34/MAVS/NLRP3-dependent manner 期刊论文
Science Bulletin, 2021, 卷号: 66, 期号: 16
作者:  Xu H.;  Yu W.;  Sun S.;  Li C.;  Ren J.;  Zhang Y.
收藏  |  浏览/下载:15/0  |  提交时间:2021/09/01
Acute myocardial infarction  Autophagic degradation  Mitochondrial antiviral signaling protein  NLRP3 inflammasome  RNF34  TAX1BP1  
IL-18 maintains the homeostasis of mucosal immune system via inflammasome-independent but microbiota-dependent manner 期刊论文
Science Bulletin, 2021
作者:  Zheng X.;  Liu L.;  Meng G.;  Zhu S.;  Zhou R.;  Jiang W.
收藏  |  浏览/下载:31/0  |  提交时间:2021/09/01
Dysbiosis  IL-18  Immune system  Inflammasome  
N-salicyloyl tryptamine derivatives as potential therapeutic agents for Alzheimer's disease with neuroprotective effects 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 115
作者:  Bai, Yinliang;  Liu, Dan;  Zhang, Honghua;  Wang, Yuying;  Wang, Degui;  Cai, Hongbin;  Wen, Huaixiu;  Yuan, Guoqiang;  An, Hui;  Wang, Yali;  Shi, Tao;  Wang, Zhen
收藏  |  浏览/下载:33/0  |  提交时间:2022/04/28
CELL-DEATH  INFLAMMASOME  PYROPTOSIS  NEUROINFLAMMATION  MICROGLIA  MECHANISM  APOPTOSIS  
Bacterial detection by NAIP/NLRC4 elicits prompt contractions of intestinal epithelial cell layers 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 16
作者:  Ventayol P.S.;  Geiser P.;  Di Martino M.L.;  Florbrant A.;  Fattinger S.A.;  Walder N.;  Sima E.;  Shao F.;  Gekara N.O.;  Sundbom M.;  Hardt W.-D.;  Webb D.-L.;  Hellström P.M.;  Eriksson J.;  Sellin M.E.
收藏  |  浏览/下载:31/0  |  提交时间:2021/05/24
Soluble α-synuclein-antibody complexes activate the NLRP3 inflammasome in hiPSC-derived microglia 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 15
作者:  Trudler D.;  Nazor K.L.;  Eisele Y.S.;  Grabauskas T.;  Dolatabadi N.;  Parker J.;  Sultan A.;  Zhong Z.;  Goodwin M.S.;  Levites Y.;  Golde T.E.;  Kelly J.W.;  Sierks M.R.;  Schork N.J.;  Karin M.;  Ambasudhan R.;  Lipton S.A.
收藏  |  浏览/下载:24/0  |  提交时间:2021/05/24
Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 10
作者:  Tengesdal I.W.;  Menon D.R.;  Osborne D.G.;  Neff C.P.;  Powers N.E.;  Gamboni F.;  Mauro A.G.;  Alessandro A.D.;  Stefanoni D.;  Henen M.A.;  Mills T.S.;  De Graaf D.M.;  Azam T.;  Vogeli B.;  Palmer B.E.;  Pietras E.M.;  DeGregori J.;  Tan A.-C.;  Joosten L.A.B.;  Fujita M.;  Dinarello C.A.;  Marchetti C.
收藏  |  浏览/下载:43/0  |  提交时间:2021/05/24
Discovery of a caspase cleavage motif antibody reveals insights into noncanonical inflammasome function 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 12
作者:  Davies C.W.;  Stowe I.;  Phung Q.T.;  Ho H.;  Bakalarski C.E.;  Gupta A.;  Zhang Y.;  Lill J.R.;  Payandeh J.;  Kayagaki N.;  Koerber J.T.
收藏  |  浏览/下载:34/0  |  提交时间:2021/05/24
The intestinal parasite Cryptosporidium is controlled by an enterocyte intrinsic inflammasome that depends on NLRP6 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 2
作者:  Sateriale A.;  Gullicksrud J.A.;  Engiles J.B.;  McLeod B.I.;  Kugler E.M.;  Henao-Mejia J.;  Zhou T.;  Ring A.M.;  Brodsky I.E.;  Hunter C.A.;  Striepen B.
收藏  |  浏览/下载:14/0  |  提交时间:2021/05/24
Recruitment of pro-IL-1α to mitochondrial cardiolipin, via shared LC3 binding domain, inhibits mitophagy and drives maximal NLRP3 activation 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 1
作者:  Dagvadorj J.;  Mikulska-Ruminska K.;  Tumurkhuu G.;  Ratsimandresy R.A.;  Carriere J.;  Andres A.M.;  Marek-Iannucci S.;  Song Y.;  Chen S.;  Lane M.;  Dorfleutner A.;  Gottlieb R.A.;  Stehlik C.;  Cassel S.;  Sutterwala F.S.;  Bahar I.;  Crother T.R.;  Arditi M.
收藏  |  浏览/下载:41/0  |  提交时间:2021/05/24