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Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells 期刊论文
, 2020, 卷号: 368, 期号: 6494
作者:  Zhou Z.;  He H.;  Wang K.;  Shi X.;  Wang Y.;  Su Y.;  Wang Y.;  Li D.;  Liu W.;  Zhang Y.;  Shen L.;  Han W.;  Shen L.;  Ding J.;  Shao F.
收藏  |  浏览/下载：26/0  |  提交时间：2020/07/28
cell  cell component  cytology  enzyme  enzyme activity  gene expression  immunity  tumor  Mus  gamma interferon  granzyme  GSDMB protein, human  GZMA protein, human  pore forming cytotoxic protein  tumor protein  animal  Bagg albino mouse  chemistry  cytotoxic T lymphocyte  enzymology  genetics  HEK293 cell line  human  immunology  metabolism  mouse  natural killer cell  neoplasm  pathology  protein degradation  protein domain  pyroptosis  transgenic mouse  Animals  Granzymes  HEK293 Cells  Humans  Interferon-gamma  Killer Cells, Natural  Mice  Mice, Inbred BALB C  Mice, Transgenic  Neoplasm Proteins  Neoplasms  Pore Forming Cytotoxic Proteins  Protein Domains  Proteolysis  Pyroptosis  T-Lymphocytes, Cytotoxic  
Enhanced sustainable green revolution yield via nitrogen-responsive chromatin modulation in rice 期刊论文
, 2020, 卷号: 367, 期号: 6478
作者:  Wu K.;  Wang S.;  Song W.;  Zhang J.;  Wang Y.;  Liu Q.;  Yu J.;  Ye Y.;  Li S.;  Chen J.;  Zhao Y.;  Wang J.;  Wu X.;  Wang M.;  Zhang Y.;  Liu B.;  Wu Y.;  Harberd N.P.;  Fu X.
收藏  |  浏览/下载：35/0  |  提交时间：2020/07/28
DELLA protein  gibberellin  gibberellin insensitive dwarf1  histone H3  polycomb repressive complex 2  receptor  transcription factor  unclassified drug  alternative agriculture  chromosome  gene expression  genetic engineering  green revolution  inhibition  molecular analysis  nitrogen  nutrient use efficiency  protein  rice  agriculture  allele  Article  chromatin immunoprecipitation  controlled study  D14 gene  gene mutation  genetic screening  genetic transcription  grain yield  green revolution  histone modification  modulation  ngr5 gene  nitrogen availability  nitrogen responsive chromatin modulation  nonhuman  OsSPL14 gene  plant gene  polymerase chain reaction  priority journal  protein protein interaction  rice  RNA sequencing  varietas  
Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2 期刊论文
, 2020, 卷号: 367, 期号: 6485
作者:  Yan R.;  Zhang Y.;  Li Y.;  Xia L.;  Guo Y.;  Zhou Q.
收藏  |  浏览/下载：17/0  |  提交时间：2020/07/28
angiotensin converting enzyme 2  coronavirus spike glycoprotein  heterodimer  homodimer  amino acid transporter  angiotensin converting enzyme 2  dipeptidyl carboxypeptidase  protein binding  SLC6A19 protein, human  spike protein, SARS-CoV-2  virus receptor  enzyme  gene  gene expression  protein  ultrastructure  virus  Article  binding site  complex formation  controlled study  coronavirus disease 2019  cryoelectron microscopy  dimerization  embryo  enzyme structure  human  human cell  nonhuman  priority journal  protein domain  SARS-related coronavirus  Severe acute respiratory syndrome coronavirus 2  amino acid sequence  Betacoronavirus  Coronavirus infection  molecular model  pandemic  protein multimerization  SARS coronavirus  sequence alignment  ultrastructure  virus pneumonia  Coronavirus  SARS coronavirus  Amino Acid Sequence  Amino Acid Transport Systems, Neutral  Betacoronavirus  Coronavirus Infections  Cryoelectron Microscopy  Humans  Models, Molecular  Pandemics  Peptidyl-Dipeptidase A  Pneumonia, Viral  Protein Binding  Protein Domains  Protein Multimerization  Receptors, Virus  SARS Virus  Sequence Alignment  Spike Glycoprotein, Coronavirus  
Structure of an active human histone pre-mRNA 3′-end processing machinery 期刊论文
, 2020, 卷号: 367, 期号: 6478
作者:  Sun Y.;  Zhang Y.;  Aik W.S.;  Yang X.-C.;  Marzluff W.F.;  Walz T.;  Dominski Z.;  Tong L.
收藏  |  浏览/下载：131/0  |  提交时间：2020/07/28
beta lactamase  cleavage and polyadenylation specificity factor  cleavage and polyadenylation specificity factor 100  cleavage and polyadenylation specificity factor 73  endonuclease  histone  membrane protein  messenger RNA precursor  recombinant protein  small nuclear ribonucleoprotein  small nuclear RNA  symplekin  U7 small nuclear ribonucleoprotein  unclassified drug  enzyme activity  genetic analysis  metazoan  protein  recombination  RNA  3' untranslated region  amino terminal sequence  Article  biochemical analysis  carboxy terminal sequence  conformational transition  controlled study  cryoelectron microscopy  enzyme active site  gene rearrangement  genetic analysis  hydrogen bond  molecular recognition  mutagenesis  polyadenylation  priority journal  protein conformation  protein protein interaction  RNA cleavage  RNA processing  RNA sequencing  Amphora  Metazoa