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Challenges Associated With Applying Physiologically Based Pharmacokinetic Modeling for Public Health Decision-Making 期刊论文
TOXICOLOGICAL SCIENCES, 2018, 卷号: 162, 期号: 2, 页码: 341-348
作者:  Tan, Yu-Mei;  Worley, Rachel R.;  Leonard, Jeremy A.;  Fisher, Jeffrey W.
收藏  |  浏览/下载:23/0  |  提交时间:2019/05/04
Refining the aggregate exposure pathway 期刊论文
ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS, 2018, 卷号: 20, 期号: 3, 页码: 428-436
作者:  Tan, Yu-Mei;  Leonard, Jeremy A.;  Edwards, Stephen;  Teeguarden, Justin;  Egeghy, Peter
收藏  |  浏览/下载:44/0  |  提交时间:2019/05/04
Investigating the state of physiologically based kinetic modelling practices and challenges associated with gaining regulatory acceptance of model applications 期刊论文
REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2017, 卷号: 90, 页码: 104-115
作者:  Paini, Alicia;  Leonard, Jeremy A.;  Kliment, Tomas;  Tan, Yu-Mei;  Worth, Andrew
收藏  |  浏览/下载:55/0  |  提交时间:2019/05/04
Expanding on Successful Concepts, Models, and Organization 期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2016, 卷号: 50, 期号: 17, 页码: 8921-8922
作者:  Teeguarden, Justin G.;  Tan, Yu-Mei;  Edwards, Stephen W.;  Leonard, Jeremy A.;  Anderson, Kim A.;  Corley, Richard A.;  Kile, Molly L.;  Simonich, Staci L. Massey;  Stone, David;  Tanguay, Robert L.;  Waters, Katrina M.;  Harper, Stacey. L.;  Williams, David E.
收藏  |  浏览/下载:42/0  |  提交时间:2019/05/04
Evaluating the Impact of Uncertainties in Clearance and Exposure When Prioritizing Chemicals Screened in High-Throughput Assays 期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2016, 卷号: 50, 期号: 11, 页码: 5961-5971
作者:  Leonard, Jeremy A.;  Leonard, Ashley Sobel;  Chang, Daniel T.;  Edwards, Stephen;  Lu, Jingtao;  Scholle, Steven;  Key, Phillip;  Winter, Maxwell;  Isaacs, Kristin;  Tan, Yu-Mei
收藏  |  浏览/下载:19/0  |  提交时间:2019/05/04
Completing the Link between Exposure Science and Toxicology for Improved Environmental Health Decision Making: The Aggregate Exposure Pathway Framework 期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2016, 卷号: 50, 期号: 9, 页码: 4579-4586
作者:  Teeguarden, Justin G.;  Tan, Yu-Mei;  Edwards, Stephen W.;  Leonard, Jeremy A.;  Anderson, Kim A.;  Corley, Richard A.;  Kile, Molly L.;  Simonich, Staci M.;  Stone, David;  Tanguay, Robert L.;  Waters, Katrina M.;  Harper, Stacey L.;  Williams, David E.
收藏  |  浏览/下载:37/0  |  提交时间:2019/05/04
Estimating Margin of Exposure to Thyroid Peroxidase Inhibitors Using High-Throughput in vitro Data, High-Throughput Exposure Modeling, and Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling 期刊论文
TOXICOLOGICAL SCIENCES, 2016, 卷号: 151, 期号: 1, 页码: 57-70
作者:  Leonard, Jeremy A.;  Tan, Yu-Mei;  Gilbert, Mary;  Isaacs, Kristin;  El-Masri, Hisham
收藏  |  浏览/下载:14/0  |  提交时间:2019/05/04
Developing a Physiologically-Based Pharmacokinetic Model Knowledgebase in Support of Provisional Model Construction 期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2016, 卷号: 12, 期号: 2
作者:  Lu, Jingtao;  Goldsmith, Michael-Rock;  Grulke, Christopher M.;  Chang, Daniel T.;  Brooks, Raina D.;  Leonard, Jeremy A.;  Phillips, Martin B.;  Hypes, Ethan D.;  Fair, Matthew J.;  Tornero-Velez, Rogelio;  Johnson, Jeffre;  Dary, Curtis C.;  Tan, Yu-Mei
收藏  |  浏览/下载:35/0  |  提交时间:2019/05/04
A Workflow to Investigate Exposure and Pharmacokinetic Influences on High-Throughput in Vitro Chemical Screening Based on Adverse Outcome Pathways 期刊论文
ENVIRONMENTAL HEALTH PERSPECTIVES, 2016, 卷号: 124, 期号: 1, 页码: 53-60
作者:  Phillips, Martin B.;  Leonard, Jeremy A.;  Grulke, Christopher M.;  Chang, Daniel T.;  Edwards, Stephen W.;  Brooks, Raina;  Goldsmith, Michael-Rock;  El-Masri, Hisham;  Tan, Yu-Mei
收藏  |  浏览/下载:28/0  |  提交时间:2019/05/04