气候变化领域集成服务门户(CCPortal): Open fire exposure increases the risk of pregnancy loss in South Asia

CCPortal

DOI	10.1038/s41467-021-23529-7
	Open fire exposure increases the risk of pregnancy loss in South Asia
	Xue T.; Geng G.; Han Y.; Wang H.; Li J.; Li H.-T.; Zhou Y.; Zhu T.
发表日期	2021
ISSN	2041-1723
卷号	12 期号:1
英文摘要	Interactions between climate change and anthropogenic activities result in increasing numbers of open fires, which have been shown to harm maternal health. However, few studies have examined the association between open fire and pregnancy loss. We conduct a self-comparison case-control study including 24,876 mothers from South Asia, the region with the heaviest pregnancy-loss burden in the world. Exposure is assessed using a chemical transport model as the concentrations of fire-sourced PM2.5 (i.e., fire PM2.5). The adjusted odds ratio (OR) of pregnancy loss for a 1-μg/m3 increment in averaged concentration of fire PM2.5 during pregnancy is estimated as 1.051 (95% confidence intervals [CI]: 1.035, 1.067). Because fire PM2.5 is more strongly linked with pregnancy loss than non-fire PM2.5 (OR: 1.014; 95% CI: 1.011, 1.016), it contributes to a non-neglectable fraction (13%) of PM2.5-associated pregnancy loss. Here, we show maternal health is threaten by gestational exposure to fire smoke in South Asia. © 2021, The Author(s).
语种	英语
scopus关键词	climate change; concentration (composition); health risk; human activity; maternal health; pollution exposure; pregnancy; risk factor; smoke; adult; Article; case control study; concentration (parameter); controlled study; disease association; disease burden; environmental exposure; female; fire; human; major clinical study; maternal welfare; mother; particulate matter 2.5; smoke; South Asia; spontaneous abortion; adverse event; air pollutant; air pollution; Asia; environmental monitoring; health survey; maternal exposure; pregnancy; risk factor; satellite imagery; smoke; spontaneous abortion; young adult; South Asia; Abortion, Spontaneous; Adult; Air Pollutants; Air Pollution; Asia; Case-Control Studies; Environmental Monitoring; Female; Fires; Health Surveys; Humans; Maternal Exposure; Maternal Health; Pregnancy; Risk Factors; Satellite Imagery; Smoke; Young Adult
来源期刊	Nature Communications
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/251432
作者单位	Institute of Reproductive and Child Health / Ministry of Health Key Laboratory of Reproductive Health and Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Centre, Beijing, China; School of Environment, Tsinghua University, Beijing, China; Environmental Research Group, MRC Centre for Environment and Health, Imperial College London, London, United Kingdom; BIC-ESAT and SKL-ESPC, College of Environmental Science and Engineering, Peking University Beijing, Beijing, China
推荐引用方式 GB/T 7714	Xue T.,Geng G.,Han Y.,et al. Open fire exposure increases the risk of pregnancy loss in South Asia[J],2021,12(1).
APA	Xue T..,Geng G..,Han Y..,Wang H..,Li J..,...&Zhu T..(2021).Open fire exposure increases the risk of pregnancy loss in South Asia.Nature Communications,12(1).
MLA	Xue T.,et al."Open fire exposure increases the risk of pregnancy loss in South Asia".Nature Communications 12.1(2021).