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An AMPK–caspase-6 axis controls liver damage in nonalcoholic steatohepatitis 期刊论文
, 2020, 卷号: 367, 期号: 6478
作者:  Zhao P.;  Sun X.;  Chaggan C.;  Liao Z.;  Wong K.I.;  He F.;  Singh S.;  Loomba R.;  Karin M.;  Witztum J.L.;  Saltiel A.R.
收藏  |  浏览/下载:35/0  |  提交时间:2020/07/28
6,7 dihydro 4 hydroxy 3 (2' hydroxy 1,1' biphenyl 4 yl) 6 oxothieno[2,3 b]pyridine 5 carbonitrile  adenosine phosphate  caspase 3  caspase 6  caspase 7  cytochrome c  hydroxymethylglutaryl coenzyme A reductase kinase  matrix metalloproteinase  apoptosis  cytochrome  enzyme  enzyme activity  inhibition  protein  rodent  AMPK signaling  animal experiment  animal model  animal tissue  apoptosis  Article  C57BL 6 mouse  cell death  controlled study  drug mechanism  enzyme activation  enzyme activity  enzyme inhibition  enzyme phosphorylation  enzyme repression  gene knockout  human  human cell  human tissue  liver cell  liver fibrosis  liver injury  male  mouse  nonalcoholic steatohepatitis  nonhuman  priority journal  protein cleavage  protein secretion  
Structural basis for transcriptional start site control of HIV-1 RNA fate 期刊论文
, 2020, 卷号: 368, 期号: 6489
作者:  Brown J.D.;  Kharytonchyk S.;  Chaudry I.;  Iyer A.S.;  Carter H.;  Becker G.;  Desai Y.;  Glang L.;  Choi S.H.;  Singh K.;  Lopresti M.W.;  Orellana M.;  Rodriguez T.;  Oboh U.;  Hijji J.;  Ghinger F.G.;  Stewart K.;  Francis D.;  Edwards B.;  Chen P.;  Case D.A.;  Telesnitsky A.;  Summers M.F.
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capped RNA  initiation factor 4E  messenger RNA  virus RNA  capped RNA  guanosine  initiation factor 4E  messenger RNA  virus RNA  cell  chemical binding  deuterium  genome  human immunodeficiency virus  physiological response  RNA  Article  base pairing  deuteron nuclear magnetic resonance  dimerization  DNA helix  energy transfer  gene control  gene function  gene number  human  Human immunodeficiency virus 1  nonhuman  priority journal  promoter region  RNA probe  RNA structure  RNA transcription  virus replication  5' untranslated region  base pairing  chemistry  DNA base composition  gene expression regulation  genetics  Human immunodeficiency virus 1  metabolism  nuclear magnetic resonance  protein synthesis  transcription initiation site  Eukaryota  Human immunodeficiency virus 1  5' Untranslated Regions  Base Composition  Base Pairing  Eukaryotic Initiation Factor-4E  Gene Expression Regulation, Viral  Guanosine  HIV-1  Humans  Nuclear Magnetic Resonance, Biomolecular  Protein Biosynthesis  RNA Caps  RNA, Messenger  RNA, Viral  Transcription Initiation Site