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Confirmation of high-throughput screening data and novel mechanistic insights into VDR-xenobiotic interactions by orthogonal assays 期刊论文
SCIENTIFIC REPORTS, 2018, 卷号: 8
作者:  Mahapatra, Debabrata;  Franzosa, Jill A.;  Roell, Kyle;  Kuenemann, Melaine Agnes;  Houck, Keith A.;  Reif, David M.;  Fourches, Denis;  Kullman, Seth W.
收藏  |  浏览/下载:34/0  |  提交时间:2019/05/04
Using ToxCast (TM) Data to Reconstruct Dynamic Cell State Trajectories and Estimate Toxicological Points of Departure 期刊论文
ENVIRONMENTAL HEALTH PERSPECTIVES, 2016, 卷号: 124, 期号: 7, 页码: 910-919
作者:  Shah, Imran;  Setzer, R. Woodrow;  Jack, John;  Houck, Keith A.;  Judson, Richard S.;  Knudsen, Thomas B.;  Liu, Jie;  Martin, Matthew T.;  Reif, David M.;  Richard, Ann M.;  Thomas, Russell S.;  Crofton, Kevin M.;  Dix, David J.;  Kavlock, Robert J.
收藏  |  浏览/下载:30/0  |  提交时间:2019/05/04
Predictive Endocrine Testing in the 21st Century Using in Vitro Assays of Estrogen Receptor Signaling Responses 期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2014, 卷号: 48, 期号: 15, 页码: 8706-8716
作者:  Rotroff, Daniel M.;  Martin, Matt T.;  Dix, David J.;  Filer, Dayne L.;  Houck, Keith A.;  Knudsen, Thomas B.;  Sipes, Nisha S.;  Reif, David M.;  Xia, Menghang;  Huang, Ruili;  Judson, Richard S.
收藏  |  浏览/下载:40/0  |  提交时间:2019/05/04
Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway 期刊论文
SCIENTIFIC REPORTS, 2014, 卷号: 4
作者:  Huang, Ruili;  Sakamuru, Srilatha;  Martin, Matt T.;  Reif, David M.;  Judson, Richard S.;  Houck, Keith A.;  Casey, Warren;  Hsieh, Jui-Hua;  Shockley, Keith R.;  Ceger, Patricia;  Fostel, Jennifer;  Witt, Kristine L.;  Tong, Weida;  Rotroff, Daniel M.;  Zhao, Tongan;  Shinn, Paul;  Simeonov, Anton;  Dix, David J.;  Austin, Christopher P.;  Kavlock, Robert J.;  Tice, Raymond R.;  Xia, Menghang
收藏  |  浏览/下载:40/0  |  提交时间:2019/05/04
Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanisms 期刊论文
NATURE BIOTECHNOLOGY, 2014, 卷号: 32, 期号: 6, 页码: 583-+
作者:  Kleinstreuer, Nicole C.;  Yang, Jian;  Berg, Ellen L.;  Knudsen, Thomas B.;  Richard, Ann M.;  Martin, Matthew T.;  Reif, David M.;  Judson, Richard S.;  Polokoff, Mark;  Dix, David J.;  Kavlock, Robert J.;  Houck, Keith A.
收藏  |  浏览/下载:32/0  |  提交时间:2019/05/04
Dosimetric Anchoring of In Vivo and In Vitro Studies for Perfluorooctanoate and Perfluorooctanesulfonate 期刊论文
TOXICOLOGICAL SCIENCES, 2013, 卷号: 136, 期号: 2, 页码: 308-327
作者:  Wambaugh, John F.;  Setzer, R. Woodrow;  Pitruzzello, Ann M.;  Liu, Jie;  Reif, David M.;  Kleinstreuer, Nicole C.;  Wang, Nina Ching Y.;  Sipes, Nisha;  Martin, Matthew;  Das, Kaberi;  DeWitt, Jamie C.;  Strynar, Mark;  Judson, Richard;  Houck, Keith A.;  Lau, Christopher
收藏  |  浏览/下载:19/0  |  提交时间:2019/05/04
Real-Time Growth Kinetics Measuring Hormone Mimicry for ToxCast Chemicals in T-47D Human Ductal Carcinoma Cells 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2013, 卷号: 26, 期号: 7, 页码: 1097-1107
作者:  Rotroff, Daniel M.;  Dix, David J.;  Houck, Keith A.;  Kavlock, Robert J.;  Knudsen, Thomas B.;  Martin, Matthew T.;  Reif, David M.;  Richard, Ann M.;  Sipes, Nisha S.;  Abassi, Yama A.;  Jin, Can;  Stampfl, Melinda;  Judson, Richard S.
收藏  |  浏览/下载:22/0  |  提交时间:2019/05/04
Profiling 976 ToxCast Chemicals across 331 Enzymatic and Receptor Signaling Assays 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2013, 卷号: 26, 期号: 6, 页码: 878-895
作者:  Sipes, Nisha S.;  Martin, Matthew T.;  Kothiya, Parth;  Reif, David M.;  Judson, Richard S.;  Richard, Ann M.;  Houck, Keith A.;  Dix, David J.;  Kavlock, Robert J.;  Knudsen, Thomas B.
收藏  |  浏览/下载:23/0  |  提交时间:2019/05/04
In Vitro Perturbations of Targets in Cancer Hallmark Processes Predict Rodent Chemical Carcinogenesis 期刊论文
TOXICOLOGICAL SCIENCES, 2013, 卷号: 131, 期号: 1, 页码: 40-55
作者:  Kleinstreuer, Nicole C.;  Dix, David J.;  Houck, Keith A.;  Kavlock, Robert J.;  Knudsen, Thomas B.;  Martin, Matthew T.;  Paul, Katie B.;  Reif, David M.;  Crofton, Kevin M.;  Hamilton, Kerry;  Hunter, Ronald;  Shah, Imran;  Judson, Richard S.
收藏  |  浏览/下载:41/0  |  提交时间:2019/05/04
Using in Vitro High Throughput Screening Assays to Identify Potential Endocrine-Disrupting Chemicals 期刊论文
ENVIRONMENTAL HEALTH PERSPECTIVES, 2013, 卷号: 121, 期号: 1, 页码: 7-14
作者:  Rotroff, Daniel M.;  Dix, David J.;  Houck, Keith A.;  Knudsen, Thomas B.;  Martin, Matthew T.;  McLaurin, Keith W.;  Reif, David M.;  Crofton, Kevin M.;  Singh, Amar V.;  Xia, Menghang;  Huang, Ruili;  Judson, Richard S.
收藏  |  浏览/下载:23/0  |  提交时间:2019/05/04